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Paper · 4530284

Nuclear triiodothyronine-binding protein: partial characterization and binding to chromatin.

Degroot LJ and 3 others. Proc Natl Acad Sci U S A, 1974. Cited by 86 papers, by iCite.

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ConductScience Library. Nuclear triiodothyronine-binding protein: partial characterization and binding to chromatin. Papers, record 4530284. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/4530284

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Nuclear triiodothyronine-binding protein: partial characterization and binding to chromatin.
PubMed
Journal
Proc Natl Acad Sci U S A
PubMed
Year
1974
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
86
iCite
Relative citation ratio, by iCite
1.82
iCite
Revised in PubMed
2019-05-01
PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Degroot LJL J
2Refetoff SS
3Strausser JJ
4Barsano CC

Source PubMed

Topics15

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Cell NucleusMajor topic
ChromatinMajor topic
ProteinsMajor topic
TriiodothyronineMajor topic
Animals
Chloromercuribenzoates
Dithiothreitol
Electrophoresis, Starch Gel
Iodine Radioisotopes
Liver
Pronase
Protein Binding
Protein Denaturation
Rats
Urea

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References17

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
15,065,814Metabolism of L-thyroxine (T4) and L-triiodothyronine (T3) by human fibroblasts in tissue culture: evidence for cellular binding proteins and conversion of T4 to T3.Endocrinology1972https://conductscience.org/library/papers/5065814PubMed
24,743,513Limited capacity binding sites for L-triiodothyronine in rat liver nuclei. Localization to the chromatin and partial characterization of the L-triiodothyronine-chromatin complex.J Biol Chem1973https://conductscience.org/library/papers/4743513PubMed
34,347,385Temperature-dependent binding of estrogen receptor to chromatin.Biochemistry1972https://conductscience.org/library/papers/4347385PubMed
44,341,781Interaction of estradiol- and progesterone-receptors with nucleoprotein: heat-labile acceptor factors.Biochim Biophys Acta1972https://conductscience.org/library/papers/4341781PubMed
55,559,842Progesterone-binding components of chick oviduct. 3. Chromatin acceptor sites.J Biol Chem1971https://conductscience.org/library/papers/5559842PubMed
64,357,872Thyroid hormone action in cell culture: domonstration of nuclear receptors in intact cells and isolated nuclei.Proc Natl Acad Sci U S A1973https://conductscience.org/library/papers/4357872PubMed
74,835,871Binding of T3 in rat liver nuclei.Endocrinology1974https://conductscience.org/library/papers/4835871PubMed
85,033,645Specific triiodothyronine binding sites in the anterior pituitary of the rat.Science1972https://conductscience.org/library/papers/5033645PubMed
913,919,772Interaction between thyroid hormones and cellular constituent. II. Intracellular distribution and the cell-sap effect.Biochim Biophys Acta1962https://conductscience.org/library/papers/13919772PubMed
104,933,311Hormone-receptor interaction as a guide to biochemical mechanism.Biochem Soc Symp1971https://conductscience.org/library/papers/4933311PubMed

Cited by13

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 86 citations.

PMIDTitleJournalYearIn PapersSource
7,364,946Direct and synergistic interactions of 3,5,3'-triiodothyronine and the adrenergic system in stimulating sugar transport by rat thymocytes.J Clin Invest1980https://conductscience.org/library/papers/7364946PubMed
6,261,237Affinity labeling of rat liver thyroid hormone nuclear receptor.Proc Natl Acad Sci U S A1980https://conductscience.org/library/papers/6261237PubMed
3,472,213Purification and characterization of rat liver nuclear thyroid hormone receptors.Proc Natl Acad Sci U S A1987https://conductscience.org/library/papers/3472213PubMed
2,693,518The molecular basis of thyroid hormone action.J Endocrinol Invest1989https://conductscience.org/library/papers/2693518PubMed
429,570Stimulation by triiodothyronine of the in vitro uptake of sugars by rat thymocytes.J Clin Invest1979https://conductscience.org/library/papers/429570PubMed
266,726Triiodothyronine stimulates specifically growth hormone mRNA in rat pituitary tumor cells.Proc Natl Acad Sci U S A1977https://conductscience.org/library/papers/266726PubMed
228,271Regulation of activity of chromatin receptors for thyroid hormone: possible involvement of histone-like proteins.Proc Natl Acad Sci U S A1979https://conductscience.org/library/papers/228271PubMed
226,578T3 receptor occupancy and metabolic responses.J Endocrinol Invest1979https://conductscience.org/library/papers/226578PubMed
226,575Nuclear receptors for thyroid hormone.J Endocrinol Invest1978https://conductscience.org/library/papers/226575PubMed
193,601The mitochondrial route of thyroid hormone action.Bull N Y Acad Med1977https://conductscience.org/library/papers/193601PubMed

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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