Paper4569769
An active antibody fragment (Fv) composed of the variable portions of heavy and light chains.
Hochman J and 2 others. Biochemistry, 1973. Cited by 134 papers, by iCite.
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ConductScience Library. An active antibody fragment (Fv) composed of the variable portions of heavy and light chains. Papers, record 4569769. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/4569769
Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- An active antibody fragment (Fv) composed of the variable portions of heavy and light chains.
- PubMed
Topics23
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Immunoglobulin A | Major topic |
| Immunoglobulin Fab Fragments | Major topic |
| Myeloma Proteins | Major topic |
| Peptides | Major topic |
| Amino Acid Sequence | |
| Amino Acids | |
| Animals | |
| Binding Sites | |
| Chromatography, DEAE-Cellulose | |
| Dansyl Compounds | |
| Electrophoresis | |
| Fluorescence | |
| Guanidines | |
| Isoelectric Focusing | |
| Macromolecular Substances | |
| Mice | |
| Molecular Weight | |
| Nitrobenzenes | |
| Pepsin A | |
| Spectrometry, Fluorescence | |
| Spectrophotometry, Ultraviolet | |
| Ultracentrifugation | |
| Urea |
Source PubMed
Cited by26
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 134 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 32,469,918 | Molecular interactions between monoclonal oligomer-specific antibody 5E3 and its amyloid beta cognates. | PLoS One | 2020 | https://conductscience.org/library/papers/32469918 | PubMed |
| 21,173,256 | Evolving concepts of specificity in immune reactions. | Proc Natl Acad Sci U S A | 2010 | https://conductscience.org/library/papers/21173256 | PubMed |
| 12,704,417 | Recombinant single-chain antibodies with various oligopeptide tails for targeted gene delivery. | Gene Ther | 2003 | https://conductscience.org/library/papers/12704417 | PubMed |
| 8,643,565 | Inhibition of immunoglobulin folding and secretion by dominant negative BiP ATPase mutants. | Proc Natl Acad Sci U S A | 1996 | https://conductscience.org/library/papers/8643565 | PubMed |
| 8,457,200 | Expression, purification and characterization of B72.3 Fv fragments. | Biochem J | 1993 | https://conductscience.org/library/papers/8457200 | PubMed |
| 6,978,921 | Helper T cell recognition of the variable domains of a mouse myeloma protein (315). Effect of the major histocompatibility complex and domain conformation. | J Exp Med | 1982 | https://conductscience.org/library/papers/6978921 | PubMed |
| 6,410,398 | Amino acid sequence of the Fv region of a human monoclonal IgM (protein WEA) with antibody activity against 3,4-pyruvylated galactose in Klebsiella polysaccharides K30 and K33. | Proc Natl Acad Sci U S A | 1983 | https://conductscience.org/library/papers/6410398 | PubMed |
| 6,227,679 | T helper cells recognize an idiotope located on peptide 88-114/117 of the light chain variable domain of an isologous myeloma protein (315). | J Exp Med | 1983 | https://conductscience.org/library/papers/6227679 | PubMed |
| 6,215,651 | A small hypervariable segment in the variable domain of an immunoglobulin light chain stimulates formation of anti-idiotypic suppressor T cells. | Proc Natl Acad Sci U S A | 1982 | https://conductscience.org/library/papers/6215651 | PubMed |
| 6,119,995 | Immunological probes in cardiovascular disease. | Br Heart J | 1982 | https://conductscience.org/library/papers/6119995 | PubMed |
| 4,605,019 | Recovery of immunoglobulin removed from lymphocytic surfaces by proteolysis. | Immunology | 1974 | https://conductscience.org/library/papers/4605019 | PubMed |
| 4,525,470 | A functional examination of hapten-binding derivatives from a murine myeloma protein with immunoglobulin features. | Proc Natl Acad Sci U S A | 1974 | https://conductscience.org/library/papers/4525470 | PubMed |
| 4,217,181 | The specificity of chain interactions among immunoglobulins. Combinations of gamma chains with kappa chains of the same subgroup as in the parent immunoglobulin G. | Biochem J | 1974 | https://conductscience.org/library/papers/4217181 | PubMed |
| 3,537,615 | Immunotherapy in the poisoned patient. Overview of present applications and future trends. | Med Toxicol | 1986 | https://conductscience.org/library/papers/3537615 | PubMed |
| 3,045,807 | Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli. | Proc Natl Acad Sci U S A | 1988 | https://conductscience.org/library/papers/3045807 | PubMed |
| 2,228,018 | Activation of idiotype-specific CD4+ T-cell line: cellular processing of exogenous self-immunoglobulin. | Immunology | 1990 | https://conductscience.org/library/papers/2228018 | PubMed |
| 1,815,591 | Biosynthetic antibody binding sites: development of a single-chain Fv model based on antidinitrophenol IgA myeloma MOPC 315. | J Protein Chem | 1991 | https://conductscience.org/library/papers/1815591 | PubMed |
| 1,409,694 | Metal-binding chimeric antibodies expressed in Escherichia coli. | Proc Natl Acad Sci U S A | 1992 | https://conductscience.org/library/papers/1409694 | PubMed |
| 921,744 | The combining site of the dinitrophenyl-binding immunoglobulin A myeloma protein MOPC 315. | Biochem J | 1977 | https://conductscience.org/library/papers/921744 | PubMed |
| 708,369 | The role of nitro groups in the binding of nitroaromatics to protein MOPC 315. | Biochem J | 1978 | https://conductscience.org/library/papers/708369 | PubMed |
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- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
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- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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