Paper · 4597451

Mutants of Escherichia coli defective in membrane phospholipid synthesis: mapping of the structural gene for L-glycerol 3-phosphate dehydrogenase.

Cronan JE and 1 other. J Bacteriol, 1974. Cited by 65 papers, by iCite.

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ConductScience Library. Mutants of Escherichia coli defective in membrane phospholipid synthesis: mapping of the structural gene for L-glycerol 3-phosphate dehydrogenase. Papers, record 4597451. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/4597451

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Mutants of Escherichia coli defective in membrane phospholipid synthesis: mapping of the structural gene for L-glycerol 3-phosphate dehydrogenase.; PubMed
Journal: J Bacteriol; PubMed
Year: 1974; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/4597451/; PubMed
DOI: https://doi.org/10.1128/jb.118.2.598-605.1974; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC246793/; PubMed
The journal: https://conductscience.org/library/journal-index/2985120R; PubMed
Citations, by iCite: 65; iCite
Relative citation ratio, by iCite: 1.91; iCite
Revised in PubMed: 2021-05-26; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Cronan JE Jr	J E
2	Bell RM	R M

Source PubMed

Topics16

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Escherichia coli	Major topic
Genes	Major topic
Glycerolphosphate Dehydrogenase	Major topic
Mutation	Major topic
Phospholipids	Major topic
Cell Membrane
Chromosome Mapping
Conjugation, Genetic
Crosses, Genetic
Genetic Complementation Test
Glycerophosphates
Recombination, Genetic
Spectrophotometry
Stereoisomerism
Temperature
Transduction, Genetic

Source PubMed

Grants0

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None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References17

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	5,335,893	Inducible system for the utilization of beta-glucosides in Escherichia coli. II. Description of mutant types and genetic analysis.	J Bacteriol	1967	https://conductscience.org/library/papers/5335893	PubMed
2	4,887,460	A mutant of Escherichia coli defective in phosphatidic acid synthesis.	Biochem Biophys Res Commun	1969	https://conductscience.org/library/papers/4887460	PubMed
3	4,389,388	Purification and regulatory properties of the biosynthetic L-glycerol 3-phosphate dehydrogenase from Escherichia coli.	J Biol Chem	1969	https://conductscience.org/library/papers/4389388	PubMed
4	4,901,354	Evidence for two genes specifically involved in unsaturated fatty acid biosynthesis in Escherichia coli.	J Bacteriol	1969	https://conductscience.org/library/papers/4901354	PubMed
5	4,912,521	Mutants of Escherichia coli K-12 with an altered glutamyl-transfer ribonucleic acid synthetase.	J Bacteriol	1970	https://conductscience.org/library/papers/4912521	PubMed
6	4,912,524	Streptomycin-suppressible lethal mutations in Escherichia coli.	J Bacteriol	1970	https://conductscience.org/library/papers/4912524	PubMed
7	4,914,564	Gene controlling L-glutamic acid decarboxylase synthesis in Escherichia coli K-12.	J Bacteriol	1970	https://conductscience.org/library/papers/4914564	PubMed
8	4,914,567	Induction of the lactose transport system in a lipid-synthesis-defective mutant of Escherichia coli.	J Bacteriol	1970	https://conductscience.org/library/papers/4914567	PubMed
9	4,943,758	Complementation studies in the maltose-A region of the Escherichia coli K12 genetic map.	J Mol Biol	1971	https://conductscience.org/library/papers/4943758	PubMed
10	4,552,305	Metabolism and function of the membrane phospholipids of Escherichia coli.	Biochim Biophys Acta	1972	https://conductscience.org/library/papers/4552305	PubMed

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Cited by33

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 65 citations.

PMID	Title	Journal	Year	In Papers	Source
35,976,526	The catalytic and structural basis of archaeal glycerophospholipid biosynthesis.	Extremophiles	2022	https://conductscience.org/library/papers/35976526	PubMed
35,255,112	The glycerol-3-phosphate dehydrogenases GpsA and GlpD constitute the oxidoreductive metabolic linchpin for Lyme disease spirochete host infectivity and persistence in the tick.	PLoS Pathog	2022	https://conductscience.org/library/papers/35255112	PubMed
32,887,610	Inducible intracellular membranes: molecular aspects and emerging applications.	Microb Cell Fact	2020	https://conductscience.org/library/papers/32887610	PubMed
27,474,711	Role of Wax Ester Synthase/Acyl Coenzyme A:Diacylglycerol Acyltransferase in Oleaginous Streptomyces sp. Strain G25.	Appl Environ Microbiol	2016	https://conductscience.org/library/papers/27474711	PubMed
26,300,876	Role of fatty acids in Bacillus environmental adaptation.	Front Microbiol	2015	https://conductscience.org/library/papers/26300876	PubMed
25,106,622	Horizontal transfers and gene losses in the phospholipid pathway of bartonella reveal clues about early ecological niches.	Genome Biol Evol	2014	https://conductscience.org/library/papers/25106622	PubMed
22,981,714	Phosphatidic acid synthesis in bacteria.	Biochim Biophys Acta	2013	https://conductscience.org/library/papers/22981714	PubMed
22,645,576	Biochemical and Molecular-Genetic Characterization of SFD1's Involvement in Lipid Metabolism and Defense Signaling.	Front Plant Sci	2012	https://conductscience.org/library/papers/22645576	PubMed
16,415,206	Involvement of a glycerol-3-phosphate dehydrogenase in modulating the NADH/NAD+ ratio provides evidence of a mitochondrial glycerol-3-phosphate shuttle in Arabidopsis.	Plant Cell	2006	https://conductscience.org/library/papers/16415206	PubMed
15,044,700	Oleic acid levels regulated by glycerolipid metabolism modulate defense gene expression in Arabidopsis.	Proc Natl Acad Sci U S A	2004	https://conductscience.org/library/papers/15044700	PubMed

1 to 10 of 33

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Genes0

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None in this release.

Drugs0

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None in this release.

Data0

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None in this release.

Data dates

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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