Paper · 4598307
Isolation and function of the gene A initiator of bacteriophage phi-chi 174, a highly specific DNA endonuclease.
Henry TJ and 1 other. Proc Natl Acad Sci U S A, 1974. Cited by 113 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. Isolation and function of the gene A initiator of bacteriophage phi-chi 174, a highly specific DNA endonuclease. Papers, record 4598307. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/4598307
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Isolation and function of the gene A initiator of bacteriophage phi-chi 174, a highly specific DNA endonuclease.
- PubMed
Topics15
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Coliphages | Major topic |
| DNA, Viral | Major topic |
| Deoxyribonucleases | Major topic |
| Genes | Major topic |
| Viral Proteins | Major topic |
| Carbon Radioisotopes | |
| Chromatography, DEAE-Cellulose | |
| DNA Replication | |
| DNA Viruses | |
| DNA, Circular | |
| DNA, Single-Stranded | |
| Electrophoresis, Polyacrylamide Gel | |
| Escherichia coli | |
| Genetic Code | |
| Virus Replication |
Source PubMed
Grants0
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None in this release.
Trials0
The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.
None in this release.
Comments and corrections0
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
None in this release.
References46
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 4,899,475 | Electrophoretic characterization of phiX174-specific proteins. | J Mol Biol | 1969 | https://conductscience.org/library/papers/4899475 | PubMed |
| 2 | 4,570,925 | Mapping of new Escherichia coli K and 15 restriction sites on specific fragments of bacteriophage phi X174. | J Virol | 1973 | https://conductscience.org/library/papers/4570925 | PubMed |
| 3 | 16,789,133 | Direction of Translation and Size of Bacteriophage phiX174 Cistrons. | J Virol | 1972 | https://conductscience.org/library/papers/16789133 | PubMed |
| 4 | 4,931,681 | Characterization and synthesis of phi X174 proteins in ultraviolet-irradiated and unirradiated cells. | J Mol Biol | 1971 | https://conductscience.org/library/papers/4931681 | PubMed |
| 5 | 4,931,510 | The mechanism of replication of phi X174 single-stranded DNA. 3. An enzymic study of the structure of the replicative form II DNA. | J Mol Biol | 1971 | https://conductscience.org/library/papers/4931510 | PubMed |
| 6 | 4,891,984 | Stages in the replication of bacteriophage phi X174 DNA in vivo. | Cold Spring Harb Symp Quant Biol | 1968 | https://conductscience.org/library/papers/4891984 | PubMed |
| 7 | 4,332,801 | Is a specific protein responsible for the supercoiling of polyoma DNA? | Nature | 1972 | https://conductscience.org/library/papers/4332801 | PubMed |
| 8 | 4,561,205 | Filamentous bacterial viruses. VI. Role of fd gene 2 in deoxyribonucleic acid replication. | J Virol | 1972 | https://conductscience.org/library/papers/4561205 | PubMed |
| 9 | 16,789,129 | Genetic Map of Bacteriophage phiX174. | J Virol | 1971 | https://conductscience.org/library/papers/16789129 | PubMed |
| 10 | 4,560,690 | Isolation of supercoiled colicinogenic factor E 1 DNA sensitive to ribonuclease and alkali. | Proc Natl Acad Sci U S A | 1972 | https://conductscience.org/library/papers/4560690 | PubMed |
1 to 10 of 46
See all 46 referencesCited by42
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 113 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 37,510,212 | Identification and Characterization of Novel SPHINX/BMMF-like DNA Sequences Isolated from Non-Bovine Foods. | Genes (Basel) | 2023 | https://conductscience.org/library/papers/37510212 | PubMed |
| 35,062,241 | A Structural Perspective of Reps from CRESS-DNA Viruses and Their Bacterial Plasmid Homologues. | Viruses | 2021 | https://conductscience.org/library/papers/35062241 | PubMed |
| 29,250,047 | The Different Faces of Rolling-Circle Replication and Its Multifunctional Initiator Proteins. | Front Microbiol | 2017 | https://conductscience.org/library/papers/29250047 | PubMed |
| 23,533,679 | Selection affects genes involved in replication during long-term evolution in experimental populations of the bacteriophage φX174. | PLoS One | 2013 | https://conductscience.org/library/papers/23533679 | PubMed |
| 16,593,485 | Cleavage of single-stranded DNA by the varphiX174 A protein: The A-single-stranded DNA covalent linkage. | Proc Natl Acad Sci U S A | 1984 | https://conductscience.org/library/papers/16593485 | PubMed |
| 6,454,113 | The A* protein of phi X174 is an inhibitor of DNA replication. | Nucleic Acids Res | 1981 | https://conductscience.org/library/papers/6454113 | PubMed |
| 6,450,942 | Cleavage and circularization of single-stranded DNA: a novel enzymatic activity of phi X174 A* protein. | Nucleic Acids Res | 1980 | https://conductscience.org/library/papers/6450942 | PubMed |
| 6,449,606 | Cleavage of phi X174 single-stranded DNA by gene A protein and formation of a tight protein-DNA complex. | J Virol | 1980 | https://conductscience.org/library/papers/6449606 | PubMed |
| 6,261,225 | The nuclease specificity of the bacteriophage phi X174 A* protein. | Nucleic Acids Res | 1981 | https://conductscience.org/library/papers/6261225 | PubMed |
| 6,254,064 | In vitro DNA replication of recombinant plasmid DNAs containing the origin of progeny replicative form DNA synthesis of phage phi X174. | Proc Natl Acad Sci U S A | 1980 | https://conductscience.org/library/papers/6254064 | PubMed |
1 to 10 of 42
See all 42 cited byGenes0
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None in this release.
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Data0
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Data dates
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- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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