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Paper · 4598307

Isolation and function of the gene A initiator of bacteriophage phi-chi 174, a highly specific DNA endonuclease.

Henry TJ and 1 other. Proc Natl Acad Sci U S A, 1974. Cited by 113 papers, by iCite.

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ConductScience Library. Isolation and function of the gene A initiator of bacteriophage phi-chi 174, a highly specific DNA endonuclease. Papers, record 4598307. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/4598307

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Isolation and function of the gene A initiator of bacteriophage phi-chi 174, a highly specific DNA endonuclease.
PubMed
Journal
Proc Natl Acad Sci U S A
PubMed
Year
1974
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
113
iCite
Relative citation ratio, by iCite
2.6
iCite
Revised in PubMed
2019-05-01
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Henry TJT J
2Knippers RR

Source PubMed

Topics15

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
ColiphagesMajor topic
DNA, ViralMajor topic
DeoxyribonucleasesMajor topic
GenesMajor topic
Viral ProteinsMajor topic
Carbon Radioisotopes
Chromatography, DEAE-Cellulose
DNA Replication
DNA Viruses
DNA, Circular
DNA, Single-Stranded
Electrophoresis, Polyacrylamide Gel
Escherichia coli
Genetic Code
Virus Replication

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References46

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
14,899,475Electrophoretic characterization of phiX174-specific proteins.J Mol Biol1969https://conductscience.org/library/papers/4899475PubMed
24,570,925Mapping of new Escherichia coli K and 15 restriction sites on specific fragments of bacteriophage phi X174.J Virol1973https://conductscience.org/library/papers/4570925PubMed
316,789,133Direction of Translation and Size of Bacteriophage phiX174 Cistrons.J Virol1972https://conductscience.org/library/papers/16789133PubMed
44,931,681Characterization and synthesis of phi X174 proteins in ultraviolet-irradiated and unirradiated cells.J Mol Biol1971https://conductscience.org/library/papers/4931681PubMed
54,931,510The mechanism of replication of phi X174 single-stranded DNA. 3. An enzymic study of the structure of the replicative form II DNA.J Mol Biol1971https://conductscience.org/library/papers/4931510PubMed
64,891,984Stages in the replication of bacteriophage phi X174 DNA in vivo.Cold Spring Harb Symp Quant Biol1968https://conductscience.org/library/papers/4891984PubMed
74,332,801Is a specific protein responsible for the supercoiling of polyoma DNA?Nature1972https://conductscience.org/library/papers/4332801PubMed
84,561,205Filamentous bacterial viruses. VI. Role of fd gene 2 in deoxyribonucleic acid replication.J Virol1972https://conductscience.org/library/papers/4561205PubMed
916,789,129Genetic Map of Bacteriophage phiX174.J Virol1971https://conductscience.org/library/papers/16789129PubMed
104,560,690Isolation of supercoiled colicinogenic factor E 1 DNA sensitive to ribonuclease and alkali.Proc Natl Acad Sci U S A1972https://conductscience.org/library/papers/4560690PubMed

Cited by42

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 113 citations.

PMIDTitleJournalYearIn PapersSource
37,510,212Identification and Characterization of Novel SPHINX/BMMF-like DNA Sequences Isolated from Non-Bovine Foods.Genes (Basel)2023https://conductscience.org/library/papers/37510212PubMed
35,062,241A Structural Perspective of Reps from CRESS-DNA Viruses and Their Bacterial Plasmid Homologues.Viruses2021https://conductscience.org/library/papers/35062241PubMed
29,250,047The Different Faces of Rolling-Circle Replication and Its Multifunctional Initiator Proteins.Front Microbiol2017https://conductscience.org/library/papers/29250047PubMed
23,533,679Selection affects genes involved in replication during long-term evolution in experimental populations of the bacteriophage φX174.PLoS One2013https://conductscience.org/library/papers/23533679PubMed
16,593,485Cleavage of single-stranded DNA by the varphiX174 A protein: The A-single-stranded DNA covalent linkage.Proc Natl Acad Sci U S A1984https://conductscience.org/library/papers/16593485PubMed
6,454,113The A* protein of phi X174 is an inhibitor of DNA replication.Nucleic Acids Res1981https://conductscience.org/library/papers/6454113PubMed
6,450,942Cleavage and circularization of single-stranded DNA: a novel enzymatic activity of phi X174 A* protein.Nucleic Acids Res1980https://conductscience.org/library/papers/6450942PubMed
6,449,606Cleavage of phi X174 single-stranded DNA by gene A protein and formation of a tight protein-DNA complex.J Virol1980https://conductscience.org/library/papers/6449606PubMed
6,261,225The nuclease specificity of the bacteriophage phi X174 A* protein.Nucleic Acids Res1981https://conductscience.org/library/papers/6261225PubMed
6,254,064In vitro DNA replication of recombinant plasmid DNAs containing the origin of progeny replicative form DNA synthesis of phage phi X174.Proc Natl Acad Sci U S A1980https://conductscience.org/library/papers/6254064PubMed

1 to 10 of 42

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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