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Paper4614

The effect of carbon dioxide on the intracellular pH and buffering power of snail neurones.

Thomas RC. J Physiol, 1976. Cited by 227 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. The effect of carbon dioxide on the intracellular pH and buffering power of snail neurones. Papers, record 4614. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/4614

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
The effect of carbon dioxide on the intracellular pH and buffering power of snail neurones.
PubMed
Journal
J Physiol
PubMed
Year
1976
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
227
iCite
Relative citation ratio, by iCite
7.39
iCite
Revised in PubMed
2019-10-26
PubMed

Authors1

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Thomas RCR C

Source PubMed

Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Carbon DioxideMajor topic
Hydrogen-Ion ConcentrationMajor topic
NeuronsMajor topic
Acetazolamide
Animals
Biological Transport, Active
Buffers
Carbonic Anhydrases
Hydrogen
In Vitro Techniques
Intracellular Fluid
Membrane Potentials
Snails

Source PubMed

References10

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
11,523Micro-electrode measurement of the internal pH of crab muscle fibres.J Physiol1975https://conductscience.org/library/papers/1523PubMed
24,443,901Proceedings: The effect of bicarbonate on the intracellular buffering power of snail neurones.J Physiol1974https://conductscience.org/library/papers/4443901PubMed
34,455,827Intracellular chloride activity and the effects of acetylcholine in snail neurones.J Physiol1974https://conductscience.org/library/papers/4455827PubMed
44,472,159Intracellular bicarbonate in single skeletal muscle fibers.Pflugers Arch1974https://conductscience.org/library/papers/4472159PubMed
54,631,687Carbonic anhydrase: isoenzymes, properties, distribution, and functional significance.Biol Rev Camb Philos Soc1972https://conductscience.org/library/papers/4631687PubMed
64,838,803Intracellular pH of snail neurones measured with a new pH-sensitive glass mirco-electrode.J Physiol1974https://conductscience.org/library/papers/4838803PubMed
75,059,237Intracellular sodium activity and the sodium pump in snail neurones.J Physiol1972https://conductscience.org/library/papers/5059237PubMed
85,793,770Buffers in the blood of the snail, Helix pomatia L.Comp Biochem Physiol1969https://conductscience.org/library/papers/5793770PubMed
95,846,926Intracellular pH and intracellular buffering power of the cat brain.Am J Physiol1965https://conductscience.org/library/papers/5846926PubMed
106,066,444A light and electron microscope study of the abdominal ganglion of Aplysia californica.J Neurophysiol1967https://conductscience.org/library/papers/6066444PubMed

Cited by91

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 227 citations.

PMIDTitleJournalYearIn PapersSource
34,986,321Carbonic anhydrase and soluble adenylate cyclase regulation of cystic fibrosis cellular phenotypes.Am J Physiol Lung Cell Mol Physiol2022https://conductscience.org/library/papers/34986321PubMed
34,679,341Understanding the Functional Expression of Na+-Coupled SLC4 Transporters in the Renal and Nervous Systems: A Review.Brain Sci2021https://conductscience.org/library/papers/34679341PubMed
31,654,410Physiological responses of Saccharomyces cerevisiae to industrially relevant conditions: Slow growth, low pH, and high CO2 levels.Biotechnol Bioeng2020https://conductscience.org/library/papers/31654410PubMed
27,981,578Bicarbonate sensing in mouse cortical astrocytes during extracellular acid/base disturbances.J Physiol2017https://conductscience.org/library/papers/27981578PubMed
27,422,823Proton Fall or Bicarbonate Rise: GLYCOLYTIC RATE IN MOUSE ASTROCYTES IS PAVED BY INTRACELLULAR ALKALINIZATION.J Biol Chem2016https://conductscience.org/library/papers/27422823PubMed
27,225,657Fluid transport by the cornea endothelium is dependent on buffering lactic acid efflux.Am J Physiol Cell Physiol2016https://conductscience.org/library/papers/27225657PubMed
25,428,855Cation-coupled bicarbonate transporters.Compr Physiol2014https://conductscience.org/library/papers/25428855PubMed
24,965,587Evidence from simultaneous intracellular- and surface-pH transients that carbonic anhydrase II enhances CO2 fluxes across Xenopus oocyte plasma membranes.Am J Physiol Cell Physiol2014https://conductscience.org/library/papers/24965587PubMed
24,592,239Intracellular pH regulation by acid-base transporters in mammalian neurons.Front Physiol2014https://conductscience.org/library/papers/24592239PubMed
24,493,747The chemistry, physiology and pathology of pH in cancer.Philos Trans R Soc Lond B Biol Sci2014https://conductscience.org/library/papers/24493747PubMed
23,506,864The SLC4 family of bicarbonate (HCO₃⁻) transporters.Mol Aspects Med2013https://conductscience.org/library/papers/23506864PubMed
23,365,805A contribution to the history of the proton channel.Wiley Interdiscip Rev Membr Transp Signal2012https://conductscience.org/library/papers/23365805PubMed
23,077,257Acidified seawater impacts sea urchin larvae pH regulatory systems relevant for calcification.Proc Natl Acad Sci U S A2012https://conductscience.org/library/papers/23077257PubMed
20,884,330Na-coupled bicarbonate transporters of the solute carrier 4 family in the nervous system: function, localization, and relevance to neurologic function.Neuroscience2010https://conductscience.org/library/papers/20884330PubMed
19,064,619The plasma membrane calcium ATPase (PMCA) of neurones is electroneutral and exchanges 2 H+ for each Ca2+ or Ba2+ ion extruded.J Physiol2009https://conductscience.org/library/papers/19064619PubMed
18,775,686Effects of chronic continuous hypoxia on the expression of SLC4A8 (NDCBE) in neonatal versus adult mouse brain.Brain Res2008https://conductscience.org/library/papers/18775686PubMed
18,359,573Expression and localization of Na-driven Cl-HCO(3)(-) exchanger (SLC4A8) in rodent CNS.Neuroscience2008https://conductscience.org/library/papers/18359573PubMed
16,651,523CO(2) signaling in guard cells: calcium sensitivity response modulation, a Ca(2+)-independent phase, and CO(2) insensitivity of the gca2 mutant.Proc Natl Acad Sci U S A2006https://conductscience.org/library/papers/16651523PubMed
16,341,877The effect of neuronal morphology and membrane-permeant weak acid and base on the dissipation of depolarization-induced pH gradients in snail neurons.Pflugers Arch2006https://conductscience.org/library/papers/16341877PubMed
14,722,772The SLC4 family of HCO 3 - transporters.Pflugers Arch2004https://conductscience.org/library/papers/14722772PubMed

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Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

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Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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