Paper · 46268

Tolerance to histocompatibility determinants in tetraparental bone marrow chimeras.

Boehmer H and 2 others. J Exp Med, 1975. Cited by 87 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Cite this record

ConductScience Library. Tolerance to histocompatibility determinants in tetraparental bone marrow chimeras. Papers, record 46268. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/46268

On this page

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Tolerance to histocompatibility determinants in tetraparental bone marrow chimeras.; PubMed
Journal: J Exp Med; PubMed
Year: 1975; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/46268/; PubMed
DOI: https://doi.org/10.1084/jem.141.2.322; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC2190519/; PubMed
The journal: https://conductscience.org/library/journal-index/2985109R; PubMed
Citations, by iCite: 87; iCite
Relative citation ratio, by iCite: 1.83; iCite
Revised in PubMed: 2019-05-08; PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Boehmer H	H
2	Sprent J	J
3	Nabholz M	M

Source PubMed

Topics16

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Bone Marrow	Major topic
Bone Marrow Cells	Major topic
Chimera	Major topic
Epitopes	Major topic
Histocompatibility Antigens	Major topic
Immune Tolerance	Major topic
Mosaicism	Major topic
Animals
Antigen-Antibody Complex
Cytotoxicity Tests, Immunologic
Lymphocyte Culture Test, Mixed
Mice
Mice, Inbred C57BL
Mice, Inbred CBA
Mice, Inbred DBA
T-Lymphocytes

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References20

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
2	6,058,691	"Intrinsic" immunological tolerance in allophenic mice.	Science	1967	https://conductscience.org/library/papers/6058691	PubMed
3	4,144,408	Cellular immunity and blocking serum activity in chimeric mice.	Cell Immunol	1973	https://conductscience.org/library/papers/4144408	PubMed
4	4,267,208	Cell-mediated lympholysis. Importance of serologically defined H-2 regions.	J Exp Med	1973	https://conductscience.org/library/papers/4267208	PubMed
5	4,272,924	Separation of T and B lymphocytes and their role in the mixed lymphocyte reaction.	J Immunol	1974	https://conductscience.org/library/papers/4272924	PubMed
6	4,277,395	Cell-mediated cell lysis in vitro: genetic control of killer cell production and target specificities in the mouse.	Eur J Immunol	1974	https://conductscience.org/library/papers/4277395	PubMed
7	4,281,718	Interaction of thymus lymphocytes with histoincompatible cells. IV. Mixed lymphocyte reactions of activated thymus lymphocytes.	Cell Immunol	1974	https://conductscience.org/library/papers/4281718	PubMed
8	4,401,189	Interaction of thymus lymphocytes with histoincompatible cells. I. Quantitation of the proliferative response of thymus cells.	Cell Immunol	1972	https://conductscience.org/library/papers/4401189	PubMed
9	4,539,312	Nature of the stimulating cell in the syngeneic and the allogeneic mixed lymphocyte reaction in mice.	J Exp Med	1972	https://conductscience.org/library/papers/4539312	PubMed
10	4,539,717	The role of the thymus in maturational development of phytohemagglutinin and pokeweed mitogen responsiveness.	Cell Immunol	1973	https://conductscience.org/library/papers/4539717	PubMed
11	4,539,846	Active suppression as a possible mechanism of tolerance in tetraparental mice.	J Exp Med	1973	https://conductscience.org/library/papers/4539846	PubMed

1 to 10 of 20

See all 20 references

Cited by33

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 87 citations.

PMID	Title	Journal	Year	In Papers	Source
27,699,263	Incomplete clonal deletion as prerequisite for tissue-specific minor antigen tolerization.	JCI Insight	2016	https://conductscience.org/library/papers/27699263	PubMed
26,039,207	T-cell depleted allogeneic hematopoietic cell transplants as a platform for adoptive therapy with leukemia selective or virus-specific T-cells.	Bone Marrow Transplant	2015	https://conductscience.org/library/papers/26039207	PubMed
24,061,772	Paternal bone marrow infusion as salvage therapy for severe GVHD following maternal haploidentical transplantation resulting in biparental chimerism.	Int J Hematol	2013	https://conductscience.org/library/papers/24061772	PubMed
17,415,881	Crossing barriers in transplantation.	J Exp Med	2007	https://conductscience.org/library/papers/17415881	PubMed
17,038,471	Can studies of tolerance ever lead to therapy?	Ann Rheum Dis	2006	https://conductscience.org/library/papers/17038471	PubMed
11,108,305	Significant MLR but not CTL responses against recipient antigens generated in T cells from bone marrow chimeras recovered from acute GVHD.	Bone Marrow Transplant	2000	https://conductscience.org/library/papers/11108305	PubMed
8,101,991	Lymphohemopoietic reconstitution using wheat germ agglutinin-positive hemopoietic stem cell transplantation within but not across the major histocompatibility antigen barriers.	Proc Natl Acad Sci U S A	1993	https://conductscience.org/library/papers/8101991	PubMed
7,635,516	Modulation of B-cell abnormalities in lupus-prone (NZB x NZW)F1 mice by normal bone marrow-derived B-lineage cells.	Immunology	1995	https://conductscience.org/library/papers/7635516	PubMed
6,971,801	Analysis of haplotype preference in the cytotoxic T-cell response to H-Y.	Immunogenetics	1981	https://conductscience.org/library/papers/6971801	PubMed
6,455,762	T cell recognition of antigen in vivo: role of the H-2 complex.	Springer Semin Immunopathol	1980	https://conductscience.org/library/papers/6455762	PubMed

1 to 10 of 33

See all 33 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this paper from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/papers/v1/46268

GET https://conductscience.org/api/papers/v1/46268/cited_by?page=2

API reference For AI assistants