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Paper · 468078

Effect of 16,16-dimethyl prostaglandin E2 on the gastric mucosal barrier.

Bolton JP and 1 other. Gut, 1979. Cited by 34 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Effect of 16,16-dimethyl prostaglandin E2 on the gastric mucosal barrier. Papers, record 468078. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/468078

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Effect of 16,16-dimethyl prostaglandin E2 on the gastric mucosal barrier.
PubMed
Journal
Gut
PubMed
Year
1979
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
34
iCite
Relative citation ratio, by iCite
2.05
iCite
Revised in PubMed
2019-05-01
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Bolton JPJ P
2Cohen MMM M

Source PubMed

Topics10

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Gastric MucosaMajor topic
Prostaglandins E, SyntheticMajor topic
Animals
Cell Membrane Permeability
Dogs
Ethanol
Female
Histamine
Potassium
Sodium

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References13

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
173,497Effect of histamine receptor antagonists on bile damage to the gastric mucosa of canine Heidenhain pouches.Gut1977https://conductscience.org/library/papers/73497PubMed
228,450Lithium: not a sensitive indicator of hydrogen ion diffusion.J Surg Res1978https://conductscience.org/library/papers/28450PubMed
3669,075Stimulation of non-parietal cell secretion in canine Heidenhain pouches by 16,16-dimethyl prostaglandin E2.Digestion1978https://conductscience.org/library/papers/669075PubMed
44,134,406Effect of 15(R)15 methylprostaglandin E2 methyl ester on healing of gastric ulcers. Controlled endoscopic study.Lancet1974https://conductscience.org/library/papers/4134406PubMed
54,633,720Permeability of gastric mucosa to hydrogen and lithium.Gastroenterology1973https://conductscience.org/library/papers/4633720PubMed
65,583,023Ethanol damage to canine oxyntic glandular mucosa.Proc Soc Exp Biol Med1967https://conductscience.org/library/papers/5583023PubMed
74,160,104Fluid produced by the gastric mucosa during damage by acetic and salicylic acids.Gastroenterology1966https://conductscience.org/library/papers/4160104PubMed
8238,904Effect of gastric secretory inhibitors on the gastric mucosal barrier.Gut1975https://conductscience.org/library/papers/238904PubMed
94,439,186Effect of histamine on isolated human gastric mucosa.Surg Forum1974https://conductscience.org/library/papers/4439186PubMed
10174,967Gastric antisecretory and antiulcer properties of PGE2, 15-methyl PGE2, and 16, 16-dimethyl PGE2. Intravenous, oral and intrajejunal administration.Gastroenterology1976https://conductscience.org/library/papers/174967PubMed

1 to 10 of 13

See all 13 references

Cited by9

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 34 citations.

PMIDTitleJournalYearIn PapersSource
7,438,956Prevention by mild irritants of gastric necrosis produced in rats by sodium taurocholate.Dig Dis Sci1980https://conductscience.org/library/papers/7438956PubMed
7,040,000A comparison of the effects of prostacyclin and the 15(S), 15-methyl analogs of PGE2 and PGF2-alpha on gastric parietal and nonparietal secretion.Dig Dis Sci1982https://conductscience.org/library/papers/7040000PubMed
7,000,631Prevention of aspirin-induced faecal blood loss by prostaglandin E2.Gut1980https://conductscience.org/library/papers/7000631PubMed
6,964,662Relationship between lesion formation and permeability of rat gastric mucosa to H+ and other cations.Br J Pharmacol1982https://conductscience.org/library/papers/6964662PubMed
6,950,895Effect of increased gastric mucosal histamine on alcohol-induced gastric damage in rats.Dig Dis Sci1982https://conductscience.org/library/papers/6950895PubMed
6,948,108Prostaglandins alter the relationship between gastric hydrogen ion concentration and flow: evidence for stimulation of non-parietal secretion in the cat.J Physiol1981https://conductscience.org/library/papers/6948108PubMed
6,133,734Newer antisecretory agents for peptic ulcer.Drugs1983https://conductscience.org/library/papers/6133734PubMed
3,125,802Gastric mucosal blood flow in misoprostol pretreated aspirin-induced ulceration.Ann Surg1988https://conductscience.org/library/papers/3125802PubMed
3,082,609Mechanisms of protective activity of 16,16-dimethyl PGE2 and acetazolamide on gastric and duodenal lesions in rats.Dig Dis Sci1986https://conductscience.org/library/papers/3082609PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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