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Paper4726

An agonist-specific effect of guanine nucleotides on binding to the beta adrenergic receptor.

Maguire ME and 2 others. Mol Pharmacol, 1976. Cited by 357 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. An agonist-specific effect of guanine nucleotides on binding to the beta adrenergic receptor. Papers, record 4726. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/4726

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
An agonist-specific effect of guanine nucleotides on binding to the beta adrenergic receptor.
PubMed
Journal
Mol Pharmacol
PubMed
Year
1976
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
357
iCite
Relative citation ratio, by iCite
8.89
iCite
Revised in PubMed
2013-11-21
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Maguire MEM E
2Van Arsdale PMP M
3Gilman AGA G

Source PubMed

Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Guanine NucleotidesMajor topic
PindololMajor topic
Receptors, AdrenergicMajor topic
Adrenergic beta-Agonists
Adrenergic beta-Antagonists
Alprenolol
Binding Sites
Binding, Competitive
Cell Line
Epinephrine
Kinetics
Protein Binding
Structure-Activity Relationship

Source PubMed

Cited by62

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 357 citations.

PMIDTitleJournalYearIn PapersSource
39,747,115Structural insights into the regulation of monomeric and dimeric apelin receptor.Nat Commun2025https://conductscience.org/library/papers/39747115PubMed
39,584,635Unraveling GPCRs Allosteric Modulation. Cannabinoid 1 Receptor as a Case Study.Proteins2025https://conductscience.org/library/papers/39584635PubMed
39,259,792Positive allosteric modulation of a GPCR ternary complex.Sci Adv2024https://conductscience.org/library/papers/39259792PubMed
39,103,320A neurodevelopmental disorder mutation locks G proteins in the transitory pre-activated state.Nat Commun2024https://conductscience.org/library/papers/39103320PubMed
35,216,076The G Protein-Coupled Serotonin 1A Receptor Augments Protein Kinase Cε-Mediated Neurogenesis in Neonatal Mouse Hippocampus-PKCε-Mediated Signaling in the Early Hippocampus.Int J Mol Sci2022https://conductscience.org/library/papers/35216076PubMed
35,106,752Community guidelines for GPCR ligand bias: IUPHAR review 32.Br J Pharmacol2022https://conductscience.org/library/papers/35106752PubMed
32,903,404A Collision Coupling Model Governs the Activation of Neuronal GIRK1/2 Channels by Muscarinic-2 Receptors.Front Pharmacol2020https://conductscience.org/library/papers/32903404PubMed
32,817,560Agonist-induced formation of unproductive receptor-G12 complexes.Proc Natl Acad Sci U S A2020https://conductscience.org/library/papers/32817560PubMed
32,046,851Reversible biotinylation of purified proteins for measuring protein-protein interactions.Methods Enzymol2020https://conductscience.org/library/papers/32046851PubMed
31,142,646Variable G protein determinants of GPCR coupling selectivity.Proc Natl Acad Sci U S A2019https://conductscience.org/library/papers/31142646PubMed
31,138,704Conformational plasticity of the intracellular cavity of GPCR-G-protein complexes leads to G-protein promiscuity and selectivity.Proc Natl Acad Sci U S A2019https://conductscience.org/library/papers/31138704PubMed
30,761,305Discovery of Pathologic GPCR Aggregation.Front Med (Lausanne)2019https://conductscience.org/library/papers/30761305PubMed
30,710,014The expanding roles and mechanisms of G protein-mediated presynaptic inhibition.J Biol Chem2019https://conductscience.org/library/papers/30710014PubMed
29,925,258The Molecular Basis of G Protein-Coupled Receptor Activation.Annu Rev Biochem2018https://conductscience.org/library/papers/29925258PubMed
29,249,607Intracellular Transfer of Na+ in an Active-State G-Protein-Coupled Receptor.Structure2018https://conductscience.org/library/papers/29249607PubMed
27,871,057Mechanistic insights into GPCR-G protein interactions.Curr Opin Struct Biol2016https://conductscience.org/library/papers/27871057PubMed
27,362,234Allosteric coupling from G protein to the agonist-binding pocket in GPCRs.Nature2016https://conductscience.org/library/papers/27362234PubMed
26,984,025The Molecular Pharmacology of G Protein Signaling Then and Now: A Tribute to Alfred G. Gilman.Mol Pharmacol2016https://conductscience.org/library/papers/26984025PubMed
25,108,041
Acute repeated intracerebroventricular injections of angiotensin II reduce agonist and antagonist radioligand binding in the paraventricular nucleus of the hypothalamus and median preoptic nucleus in the rat brain.
Brain Res2014https://conductscience.org/library/papers/25108041PubMed
23,759,942Molecular properties of muscarinic acetylcholine receptors.Proc Jpn Acad Ser B Phys Biol Sci2013https://conductscience.org/library/papers/23759942PubMed

See all 62 cited by

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
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  • References
  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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