Paper · 4902142

Isolation of an E. coli strain with a mutation affecting DNA polymerase.

De Lucia P and 1 other. Nature, 1969. Cited by 695 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Isolation of an E. coli strain with a mutation affecting DNA polymerase. Papers, record 4902142. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/4902142

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Isolation of an E. coli strain with a mutation affecting DNA polymerase.; PubMed
Journal: Nature; PubMed
Year: 1969; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/4902142/; PubMed
DOI: https://doi.org/10.1038/2241164a0; PubMed
The journal: https://conductscience.org/library/journal-index/0410462; PubMed
Citations, by iCite: 695; iCite
Revised in PubMed: 2019-06-17; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	De Lucia P	P
2	Cairns J	J

Source PubMed

Topics4

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
DNA Nucleotidyltransferases	Major topic
Escherichia coli	Major topic
Mutation	Major topic
Bacteriological Techniques

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by281

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 695 citations.

PMID	Title	Journal	Year	In Papers	Source
42,261,889	DNA polymerase I: structure, activity, and function in bacterial DNA replication and repair.	Crit Rev Biochem Mol Biol	2026	https://conductscience.org/library/papers/42261889	PubMed
40,001,506	60 Years of Studies into the Initiation of Chromosome Replication in Bacteria.	Biomolecules	2025	https://conductscience.org/library/papers/40001506	PubMed
38,666,816	Inhibitors against DNA Polymerase I Family of Enzymes: Novel Targets and Opportunities.	Biology (Basel)	2024	https://conductscience.org/library/papers/38666816	PubMed
37,146,086	Bacillus subtilis encodes a discrete flap endonuclease that cleaves RNA-DNA hybrids.	PLoS Genet	2023	https://conductscience.org/library/papers/37146086	PubMed
31,119,812	Where to begin? Sigma factors and the selectivity of transcription initiation in bacteria.	Mol Microbiol	2019	https://conductscience.org/library/papers/31119812	PubMed
30,530,516	Exonuclease III (XthA) Enforces In Vivo DNA Cloning of Escherichia coli To Create Cohesive Ends.	J Bacteriol	2019	https://conductscience.org/library/papers/30530516	PubMed
28,496,054	Days weaving the lagging strand synthesis of DNA - A personal recollection of the discovery of Okazaki fragments and studies on discontinuous replication mechanism.	Proc Jpn Acad Ser B Phys Biol Sci	2017	https://conductscience.org/library/papers/28496054	PubMed
27,789,781	The DnaE polymerase from Deinococcus radiodurans features RecA-dependent DNA polymerase activity.	Biosci Rep	2016	https://conductscience.org/library/papers/27789781	PubMed
27,458,638	Inducing stable reversion to achieve cancer control.	Nat Rev Cancer	2016	https://conductscience.org/library/papers/27458638	PubMed
27,050,298	Escherichia coli DnaE Polymerase Couples Pyrophosphatase Activity to DNA Replication.	PLoS One	2016	https://conductscience.org/library/papers/27050298	PubMed

1 to 10 of 281

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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