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Paper · 500124

The genetic control of antibody affinity. Evidence from breeding studies with mice selectively bred for either high or low affinity antibody production.

Steward MW and 2 others. Immunology, 1979. Cited by 18 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. The genetic control of antibody affinity. Evidence from breeding studies with mice selectively bred for either high or low affinity antibody production. Papers, record 500124. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/500124

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
The genetic control of antibody affinity. Evidence from breeding studies with mice selectively bred for either high or low affinity antibody production.
PubMed
Journal
Immunology
PubMed
Year
1979
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
18
iCite
Relative citation ratio, by iCite
0.4
iCite
Revised in PubMed
2018-11-13
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Steward MWM W
2Reinhardt MCM C
3Staines NAN A

Source PubMed

Topics9

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Antibody AffinityMajor topic
Selection, GeneticMajor topic
Animals
Antibody Formation
Crosses, Genetic
Histocompatibility Testing
Hybridization, Genetic
Immunogenetics
Mice

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References18

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
1137,092Macrophage clearance function and immune complex disease in New Zealand Black/White F1 hybrid mice.Clin Exp Immunol1976https://conductscience.org/library/papers/137092PubMed
2721,135Studies on the control of antibody synthesis. XII. Genetic influences on antibody affinity.Immunology1978https://conductscience.org/library/papers/721135PubMed
31,027,713Evidence for the genetic control of antibody affinity from breeding studies with inbred mouse strains producing high and low affinity antibody.Immunology1976https://conductscience.org/library/papers/1027713PubMed
44,116,216A comparison of the immune response to DNP in mice genetically selected for high or low antibody synthesis.Immunochemistry1972https://conductscience.org/library/papers/4116216PubMed
54,139,230Inheritance of antibody specificity. I. Anti-(4-hydroxy-3-nitrophenyl)acetyl of the mouse primary response.J Exp Med1974https://conductscience.org/library/papers/4139230PubMed
64,109,878Histocompatibility-linked immune response genes.Science1972https://conductscience.org/library/papers/4109878PubMed
74,282,849Inter-mouse strain differences in macrophage function and its relationship to antibody responses.Clin Exp Immunol1974https://conductscience.org/library/papers/4282849PubMed
84,213,909The genetic control of antibody binding constants and specificities in inbred rats.J Immunol1974https://conductscience.org/library/papers/4213909PubMed
959,780Studies on the genetic control of antibody affinity: the independent control of antibody levels and affinity in Biozzi mice.J Immunol1976https://conductscience.org/library/papers/59780PubMed
1056,323Expression of major histocompatibility complex antigens on different cell types.Isr J Med Sci1975https://conductscience.org/library/papers/56323PubMed

1 to 10 of 18

See all 18 references

Cited by9

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 18 citations.

PMIDTitleJournalYearIn PapersSource
14,616,795Avidity progression of dietary antibodies in healthy and coeliac children.Clin Exp Immunol2003https://conductscience.org/library/papers/14616795PubMed
8,287,607Low antibody affinity restricted to the IgA isotype in IgA nephropathy.Clin Exp Immunol1994https://conductscience.org/library/papers/8287607PubMed
6,459,898The effect of protein deficiency on the development of chronic antigen-antibody complex disease in mice.Clin Exp Immunol1981https://conductscience.org/library/papers/6459898PubMed
6,449,473The induction of chronic antigen-antibody complex disease in selectively bred mice producing either high or low affinity antibody to protein antigens.Immunology1980https://conductscience.org/library/papers/6449473PubMed
2,335,373Experimental allergic encephalomyelitis (EAE) in mice selectively bred to produce high affinity (HA) or low affinity (LA) antibody responses.Immunology1990https://conductscience.org/library/papers/2335373PubMed
1,477,799Antibody avidity in swine lymphocyte antigen-defined miniature pigs.Can J Vet Res1992https://conductscience.org/library/papers/1477799PubMed
521,058Antibody affinity and clearance function studies in high and low antibody affinity mice. The effect of protein deficiency.Immunology1979https://conductscience.org/library/papers/521058PubMed
161,213Chronic immune complex disease in mice: the role of antibody affinity.Clin Exp Immunol1979https://conductscience.org/library/papers/161213PubMed
160,420Antibody affinity: immunogenetic aspects and relationship to immune complex disease.J Clin Pathol Suppl (R Coll Pathol)1979https://conductscience.org/library/papers/160420PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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