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Paper · 53263

The major histocompatibility complex determines susceptibility to cytotoxic T cells directed against minor histocompatibility antigens.

Bevan MJ. J Exp Med, 1975. Cited by 551 papers, by iCite.

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ConductScience Library. The major histocompatibility complex determines susceptibility to cytotoxic T cells directed against minor histocompatibility antigens. Papers, record 53263. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/53263

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
The major histocompatibility complex determines susceptibility to cytotoxic T cells directed against minor histocompatibility antigens.
PubMed
Journal
J Exp Med
PubMed
Year
1975
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
551
iCite
Relative citation ratio, by iCite
10.5
iCite
Revised in PubMed
2019-05-08
PubMed

Authors1

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Bevan MJM J

Source PubMed

Topics15

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
GenesMajor topic
HistocompatibilityMajor topic
T-LymphocytesMajor topic
Animals
Cell Line
Cytotoxicity Tests, Immunologic
Epitopes
Histocompatibility Antigens
Isoantigens
Mice
Mice, Inbred BALB C
Mice, Inbred Strains
Species Specificity
Spleen
Transplantation, Homologous

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References24

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
149,564A biological role for the major histocompatibility antigens.Lancet1975https://conductscience.org/library/papers/49564PubMed
25,025,438Rejection of ascites tumor allografts. I. Isolation, characterization, and in vitro reactivity of peritoneal lymphoid effector cells from BALB-c mice immune to EL4 leukosis.J Exp Med1972https://conductscience.org/library/papers/5025438PubMed
35,682,942Quantitative studies on the mixed lymphocyte interaction in rats. 3. Kinetics of the response.J Exp Med1968https://conductscience.org/library/papers/5682942PubMed
41,078,719Genes required for cytotoxicity against virus-infected target cells in K and D regions of H-2 complex.Nature1975https://conductscience.org/library/papers/1078719PubMed
51,079,924Interaction antigens detected by cytotoxic T cells with the major histocompatibility complex as modifier.Nature1975https://conductscience.org/library/papers/1079924PubMed
61,086,219Cell-medicated cytotoxicity against ectromelia virus-infected target cells. III. Role of the H-2 gene complex.Eur J Immunol1975https://conductscience.org/library/papers/1086219PubMed
71,086,229Target cell-dependent T cell-mediated lysis of vaccinia virus-infected cells.Eur J Immunol1975https://conductscience.org/library/papers/1086229PubMed
81,090,698Cell interactions between histoincompatible T and B lymphocytes. VII. Cooperative responses between lymphocytes are controlled by genes in the I region of the H-2 complex.J Exp Med1975https://conductscience.org/library/papers/1090698PubMed
9123,002H-2 compatibility is required for T-cell-mediated lysis of target cells infected with lymphocytic choriomeningitis virus.J Exp Med1975https://conductscience.org/library/papers/123002PubMed
10123,256Alloimmune cytotoxic T cells: Evidence that they recognize serologically defined antigens and bear clonally restricted receptors.J Immunol1975https://conductscience.org/library/papers/123256PubMed

1 to 10 of 24

See all 24 references

Cited by135

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 551 citations.

PMIDTitleJournalYearIn PapersSource
42,393,377A guide to CAR T cell therapies: development, current status and future prospects.Nat Rev Immunol2026https://conductscience.org/library/papers/42393377PubMed
34,485,921Engineering enhanced CAR T-cells for improved cancer therapy.Nat Cancer2021https://conductscience.org/library/papers/34485921PubMed
30,687,803Peter Doherty, Nobel Laureate: Questions and Reflections Concerning MHC Restriction and other Fruits of a Life of Biomedical Erudition.Pathog Immun2018https://conductscience.org/library/papers/30687803PubMed
30,479,379Models of immune selection for multi-locus antigenic diversity of pathogens.Nat Rev Immunol2019https://conductscience.org/library/papers/30479379PubMed
25,818,864Codification of bidentate pMHC interaction with TCR and its co-receptor.Trends Immunol2015https://conductscience.org/library/papers/25818864PubMed
25,750,245
Medawar's legacy to cellular immunology and clinical transplantation: a commentary on Billingham, Brent and Medawar (1956) 'Quantitative studies on tissue transplantation immunity. III. Actively acquired tolerance'.
Philos Trans R Soc Lond B Biol Sci2015https://conductscience.org/library/papers/25750245PubMed
22,457,925A new cytotoxic lymphocyte-defined antigen coded by a gene closely linked to the H-3 locus.Immunogenetics1980https://conductscience.org/library/papers/22457925PubMed
21,302,087Detection of two allotype-(Ig-1)-linked minor histocompatibility loci by the use ofH-2-restricted cytotoxic lymphocytes in congenic mice.Immunogenetics1978https://conductscience.org/library/papers/21302087PubMed
18,154,613Special regulatory T-cell review: Regulation of immune responses--examining the role of T cells.Immunology2008https://conductscience.org/library/papers/18154613PubMed
9,379,075Conformational changes in MHC class I molecules. Antibody, T-cell receptor, and NK cell recognition in an HLA-B7 model system.Immunol Res1997https://conductscience.org/library/papers/9379075PubMed

1 to 10 of 135

See all 135 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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