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Paper57904

Detection of HBSAG in fixed liver tissue - use of a modified immunofluorescent technique and comparison with histochemical methods.

Portmann B and 4 others. Gut, 1976. Cited by 73 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Detection of HBSAG in fixed liver tissue - use of a modified immunofluorescent technique and comparison with histochemical methods. Papers, record 57904. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/57904

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Detection of HBSAG in fixed liver tissue - use of a modified immunofluorescent technique and comparison with histochemical methods.
PubMed
Journal
Gut
PubMed
Year
1976
PubMed
Publication types
Comparative Study, Journal Article
PubMed
Citations, by iCite
73
iCite
Relative citation ratio, by iCite
3.7
iCite
Revised in PubMed
2019-05-01
PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Portmann BB
2Galbraith RMR M
3Eddleston ALA L
4Zuckerman AJA J
5Williams RR

Source PubMed

Topics11

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Fluorescent Antibody TechniqueMajor topic
Hepatitis B AntigensMajor topic
LiverMajor topic
Acute Disease
Carcinoma, Hepatocellular
Chronic Disease
Hepatitis
Humans
Liver Cirrhosis
Liver Neoplasms
Staining and Labeling

Source PubMed

References14

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
11,080,125Cell-mediated immunity to hepatitis B surface antigen in blood donors with persistent antigenaemia.Gut1975https://conductscience.org/library/papers/1080125PubMed
21,089,835Pattern of core and surface expression in liver tissue reflects state of specific immune response in hepatitis B.Lab Invest1975https://conductscience.org/library/papers/1089835PubMed
31,095,532Immunoperoxidase localisation of hepatitis B antigen (HB) in formalin-paraffin processed liver tissue.Histochemistry1975https://conductscience.org/library/papers/1095532PubMed
41,125,673Cellular and humoral immunity to hepatitis-B surface antigen in active chronic hepatitis.Br Med J1975https://conductscience.org/library/papers/1125673PubMed
51,127,118Electron microscopy of serum of healthy hepatitis B antigen carriers.J Clin Pathol1975https://conductscience.org/library/papers/1127118PubMed
64,112,365Cytoplasmic localisation of Australia antigen in the liver.Lancet1972https://conductscience.org/library/papers/4112365PubMed
74,333,813Investigations of liver biopsies for Australia antigen by immunofluorescent technique.Clin Exp Immunol1971https://conductscience.org/library/papers/4333813PubMed
84,354,081Australia antigen in liver tissue--an immunofluorescent and immunoelectron microscopic study.Jpn J Exp Med1973https://conductscience.org/library/papers/4354081PubMed
94,363,514Staining methods of Australia antigen in paraffin section--detection of cytoplasmic inclusion bodies.Jpn J Exp Med1974https://conductscience.org/library/papers/4363514PubMed
104,582,440Cytoplasmic hepatitis B antigen in "ground-glass" hepatocytes of carriers.Arch Pathol1973https://conductscience.org/library/papers/4582440PubMed
1146,499Letter: HBAg on liver-cell surface in viral hepatitis.Lancet1975https://conductscience.org/library/papers/46499PubMed
1246,904Immunofluorescent detection of hepatitis B antigen in paraffin-embedded liver tissue.J Immunol Methods1975https://conductscience.org/library/papers/46904PubMed
1347,336Orcein staining of hepatitis B antigen in paraffin sections of liver biopsies.J Clin Pathol1975https://conductscience.org/library/papers/47336PubMed
144,911,697The localization of Australia antigen by immunofluorescence.J Exp Med1970https://conductscience.org/library/papers/4911697PubMed

Cited by19

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 73 citations.

PMIDTitleJournalYearIn PapersSource
7,456,324Hepatic morphologic findings and viral antigens in acute hepatitis B. A longitudinal study.Virchows Arch A Pathol Anat Histol1980https://conductscience.org/library/papers/7456324PubMed
7,344,523The influence of dietary molybdenum and copper supplementation on the contents of serum uric acid and some trace elements in cocks.Acta Vet Scand1981https://conductscience.org/library/papers/7344523PubMed
6,768,535Evidence for hepatitis B and other virus infection in HBsAg-negative chronic active hepatitis.Dig Dis Sci1980https://conductscience.org/library/papers/6768535PubMed
6,337,208Production of monoclonal antibodies to hepatitis B surface and core antigens, and use in the detection of viral antigens in liver biopsies.J Hyg (Lond)1983https://conductscience.org/library/papers/6337208PubMed
6,192,112Repeated application of first-layer antiserum improves immunofluorescence staining: a modification of the indirect immunofluorescence staining procedure.Histochem J1983https://conductscience.org/library/papers/6192112PubMed
6,185,545Value of copper-associated protein in diagnostic assessment of liver biopsy.J Clin Pathol1983https://conductscience.org/library/papers/6185545PubMed
6,176,600Use of orcein in detecting hepatitis B antigen in paraffin sections of liver.J Clin Pathol1982https://conductscience.org/library/papers/6176600PubMed
1,856,286Detection of hepatitis B virus pre-S1 and pre-S2 determinants in paraffin wax embedded liver tissue: importance of reagents used.J Clin Pathol1991https://conductscience.org/library/papers/1856286PubMed
856,683Immune responses to the hepatitis B surface antigen and liver-specific lipoprotein in acute type B hepatitis.Gut1977https://conductscience.org/library/papers/856683PubMed
836,677The role of the pathologist in environmental medicine and public health.Am J Pathol1977https://conductscience.org/library/papers/836677PubMed
776,335Immune response to HBsAg and the spectrum of liver lesions in HBsAg-positive patients with chronic renal disease.Br Med J1976https://conductscience.org/library/papers/776335PubMed
519,221De novo acute infection and reactivation of hepatitis B virus in established cirrhosis.Br Med J1979https://conductscience.org/library/papers/519221PubMed
306,323T lymphocyte-mediated cytotoxicity in HBsAg-positive liver disease.Clin Exp Immunol1978https://conductscience.org/library/papers/306323PubMed
219,038Hepatitis B virus antigens in primary hepatic carcinoma: immunofluorescent techniques on fixed liver tissue.J Clin Pathol1978https://conductscience.org/library/papers/219038PubMed
194,927Aetiology of cirrhosis, hepatic fibrosis, and hepatocellular carcinoma.J Clin Pathol1977https://conductscience.org/library/papers/194927PubMed
160,117Detection of HBsAg containing cells in liver biopsies by different stains and classification of positively reacting ground-glass hepatocytes.Virchows Arch A Pathol Anat Histol1979https://conductscience.org/library/papers/160117PubMed
145,724Immunohistochemical patterns of hepatitis B surface antigen (HBsAg) in patients with hepatitis, renal homografts recipients and normal carriers.Virchows Arch A Pathol Anat Histol1977https://conductscience.org/library/papers/145724PubMed
69,633HBsAg and HBcAg in the livers of asymptomatic hepatitis B antigen carriers.J Clin Pathol1977https://conductscience.org/library/papers/69633PubMed
68,037Methods for detection of hepatitis B surface antigen in paraffin sections of liver: a guideline for their use.J Clin Pathol1977https://conductscience.org/library/papers/68037PubMed

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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