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Paper60130

Observations on the pyridoxal 5'-phosphate inhibition of DNA polymerases.

Modak MJ. Biochemistry, 1976. Cited by 97 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Observations on the pyridoxal 5'-phosphate inhibition of DNA polymerases. Papers, record 60130. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/60130

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Observations on the pyridoxal 5'-phosphate inhibition of DNA polymerases.
PubMed
Journal
Biochemistry
PubMed
Year
1976
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
97
iCite
Relative citation ratio, by iCite
2.54
iCite
Revised in PubMed
2019-06-12
PubMed

Authors1

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Modak MJM J

Source PubMed

Topics15

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
DNA NucleotidyltransferasesMajor topic
Pyridoxal PhosphateMajor topic
Animals
Avian Myeloblastosis Virus
Binding Sites
Kinetics
Magnesium
Manganese
Protein Binding
Rats
Rauscher Virus
Reverse Transcriptase Inhibitors
Species Specificity
Structure-Activity Relationship
Templates, Genetic

Source PubMed

Cited by7

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 97 citations.

PMIDTitleJournalYearIn PapersSource
20,175,991Inactivation of NEIL2 DNA glycosylase by pyridoxal phosphate reveals a loop important for substrate binding.Biochem Biophys Res Commun2010https://conductscience.org/library/papers/20175991PubMed
15,494,452Pyridoxal 5'-phosphate inactivates DNA topoisomerase IB by modifying the lysine general acid.Nucleic Acids Res2004https://conductscience.org/library/papers/15494452PubMed
7,619,063Vitamin B6 modulates expression of albumin gene by inactivating tissue-specific DNA-binding protein in rat liver.Biochem J1995https://conductscience.org/library/papers/7619063PubMed
6,178,842DNA-processing activities associated with the purified alpha, beta 2, and alpha beta molecular forms of avian sarcoma virus RNA-dependent DNA polymerase.J Virol1982https://conductscience.org/library/papers/6178842PubMed
6,160,474Study of the interactions between avian myeloblastosis virus reverse transcriptase and primer tRNA. Affinity labeling and inactivation of the enzyme by periodate-treated tRNATrp.Nucleic Acids Res1980https://conductscience.org/library/papers/6160474PubMed
503,844The mode of inhibitory action by pyridoxal 5-phosphate on DNA polymerase-alpha and -beta.Nucleic Acids Res1979https://conductscience.org/library/papers/503844PubMed
67,222Specific inhibition of DNA polymerase-associated RNase H by DNA.J Virol1977https://conductscience.org/library/papers/67222PubMed

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • References
  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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