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Paper · 62014

Effects of anti-Ia sera on mitogenic responses. III. Mapping the genes controlling the expression of Ia determinants on concanavalin A-reactive cells to the I-J subregion of the H-2 gene complex.

Frelinger JA and 2 others. J Exp Med, 1976. Cited by 51 papers, by iCite.

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ConductScience Library. Effects of anti-Ia sera on mitogenic responses. III. Mapping the genes controlling the expression of Ia determinants on concanavalin A-reactive cells to the I-J subregion of the H-2 gene complex. Papers, record 62014. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/62014

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Effects of anti-Ia sera on mitogenic responses. III. Mapping the genes controlling the expression of Ia determinants on concanavalin A-reactive cells to the I-J subregion of the H-2 gene complex.
PubMed
Journal
J Exp Med
PubMed
Year
1976
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
51
iCite
Relative citation ratio, by iCite
1.16
iCite
Revised in PubMed
2019-05-08
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Frelinger JAJ A
2Niederhuber JEJ E
3Shreffler DCD C

Source PubMed

Topics12

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Chromosome MappingMajor topic
GenesMajor topic
Histocompatibility AntigensMajor topic
T-LymphocytesMajor topic
Animals
Antibodies
Concanavalin A
Epitopes
Lymphocyte Activation
Mice
Recombination, Genetic
Spleen

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References14

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
11,081,105Effects of anti-Ia serum on mitogenic responses. I. Inhibition of the proliferative response to B cell mitogen, LPS, by specific anti-Ia sera.J Immunol1975https://conductscience.org/library/papers/1081105PubMed
21,081,574The Fc receptor on thymus-derived lymphocytes: II. Mitogen responsiveness of T lymphocytes bearing the Fc receptor.J Exp Med1975https://conductscience.org/library/papers/1081574PubMed
31,082,489Effects of anti-Ia sera on mitogenic responses. II. Differential expression of the Ia marker on phytohemagglutinin and concanavalin A-reactive T cells.J Exp Med1976https://conductscience.org/library/papers/1082489PubMed
41,083,887
Separation of helper T cells from suppressor T cells expressing different Ly components. I. Polyclonal activation: suppressor and helper activities are inherent properties of distinct T-cell subclasses.
J Exp Med1976https://conductscience.org/library/papers/1083887PubMed
51,097,521Ia alloantigen(s) detected on thymocytes by use of a fluorescence-activated cell sorter.J Immunol1975https://conductscience.org/library/papers/1097521PubMed
61,102,601Ly antigens: markers of T cell function on mouse spleen cells.J Immunol1975https://conductscience.org/library/papers/1102601PubMed
759,969Expression of Ia antigens on T and B cells and their relationship to immune-response functions.Transplant Rev1976https://conductscience.org/library/papers/59969PubMed
84,128,439A mouse B-cell alloantigen determined by gene(s) linked to the major histocompatibility complex.J Exp Med1973https://conductscience.org/library/papers/4128439PubMed
94,547,437Evidence for the expression of Ia (H-2-associated) antigens on thymus-derived lymphocytes.J Exp Med1974https://conductscience.org/library/papers/4547437PubMed
104,587,740A rapid method for the isolation of functional thymus-derived murine lymphocytes.Eur J Immunol1973https://conductscience.org/library/papers/4587740PubMed

1 to 10 of 14

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Cited by19

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 51 citations.

PMIDTitleJournalYearIn PapersSource
6,769,122In vivo or in vitro treatments with anti-I-J alloantisera abolish immunity to AKR leukemia.Proc Natl Acad Sci U S A1980https://conductscience.org/library/papers/6769122PubMed
6,461,456The use of concanavalin A to study the immunoregulation of human T cells.Clin Exp Immunol1981https://conductscience.org/library/papers/6461456PubMed
6,252,100Characterization of responding cells in oxidative mitogen stimulation. III. Presence of I-A- and I-J, E, C-subregion gene products on the surface of required cells.Immunogenetics1980https://conductscience.org/library/papers/6252100PubMed
6,202,816T cell surface I-J glycoprotein. Concerted action of chromosome-4 and -17 genes forms an epitope dependent on alpha-D-mannosyl residues.J Exp Med1984https://conductscience.org/library/papers/6202816PubMed
6,170,715Monoclonal antibodies that recognize the product controlled by a gene in the I-J subregion of the mouse H-2 complex.J Exp Med1981https://conductscience.org/library/papers/6170715PubMed
6,168,577A non-T:non-B cell bears I-A, I-E, I-J, and Tla (Qa-1?) determinants.Immunogenetics1981https://conductscience.org/library/papers/6168577PubMed
762,500Distribution of lymphocytes identified by surface markers in murine strains with systemic lupus erythematosus-like syndromes.J Exp Med1979https://conductscience.org/library/papers/762500PubMed
468,309Differences in [3H]-thymidine uptake of lymph node cells stimulated by Con A and PHA in H-2 congenic mouse strains.Immunology1979https://conductscience.org/library/papers/468309PubMed
330,792Genetic control of lymphocyte activation: lack of response to low doses of concanavalin A in lipopolysaccharide-nonresponder mice.J Exp Med1977https://conductscience.org/library/papers/330792PubMed
304,531Electrophoretic mobility as a sensitive probe of lectin-lymphocyte interaction.Nature1978https://conductscience.org/library/papers/304531PubMed

1 to 10 of 19

See all 19 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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