Paper · 625326

Carcinogen-induced chromosome breakage in Fanconi's anaemia heterozygous cells.

Auerbach AD and 1 other. Nature, 1978. Cited by 75 papers, by iCite.

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ConductScience Library. Carcinogen-induced chromosome breakage in Fanconi's anaemia heterozygous cells. Papers, record 625326. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/625326

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Carcinogen-induced chromosome breakage in Fanconi's anaemia heterozygous cells.; PubMed
Journal: Nature; PubMed
Year: 1978; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/625326/; PubMed
DOI: https://doi.org/10.1038/271069a0; PubMed
The journal: https://conductscience.org/library/journal-index/0410462; PubMed
Citations, by iCite: 75; iCite
Relative citation ratio, by iCite: 2.72; iCite
Revised in PubMed: 2026-10-10; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Auerbach AD	A D
2	Wolman SR	S R

Source PubMed

Topics8

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Alkylating Agents	Major topic
Anemia, Aplastic	Major topic
Carcinogens	Major topic
Chromosome Aberrations	Major topic
Fanconi Anemia	Major topic
Chromosome Deletion
Heterozygote
Neoplasms

Source PubMed

Grants0

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None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References14

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	5,365,572	Chromosomal peculiarities and "in vitro" examinations in Fanconi's anaemia.	Humangenetik	1969	https://conductscience.org/library/papers/5365572	PubMed
2	4,288,245	Susceptibility of human diploid fibroblast strains to transformation by SV40 virus.	Science	1966	https://conductscience.org/library/papers/4288245	PubMed
3	1,065,896	Deficiency of gamma-ray excision repair in skin fibroblasts from patients with Fanconi's anemia.	Proc Natl Acad Sci U S A	1976	https://conductscience.org/library/papers/1065896	PubMed
4	4,851,278	Defective DNA repair in Fanconi's anaemia.	Nature	1974	https://conductscience.org/library/papers/4851278	PubMed
5	4,827,364	A maximum-likelihood method for estimating the disease predisposition of heterozygotes.	Am J Hum Genet	1974	https://conductscience.org/library/papers/4827364	PubMed
6	4,352,739	A high susceptibility of Fanconi's anemia to chromosome breakage by DNA cross-linking agents.	Cancer Res	1973	https://conductscience.org/library/papers/4352739	PubMed
7	4,557,110	Genes which increase chromosomal instability in somatic cells and predispose to cancer.	Prog Med Genet	1972	https://conductscience.org/library/papers/4557110	PubMed
8	4,356,745	DNA repair capacity and susceptibility to chromosome breakage in xeroderma pigmentosum cells.	Mutat Res	1973	https://conductscience.org/library/papers/4356745	PubMed
9	4,927,726	Fanconi's anaemia in the genetics of neoplasia.	Nature	1971	https://conductscience.org/library/papers/4927726	PubMed
10	4,694,815	Chromosome aberrations in xeroderma pigmentosum cells exposed to the carcinogens, 4-nitroquinoline-1-oxide and N-methyl-N'-nitrosoguanidine.	Proc Soc Exp Biol Med	1973	https://conductscience.org/library/papers/4694815	PubMed

1 to 10 of 14

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Cited by21

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 75 citations.

PMID	Title	Journal	Year	In Papers	Source
15,822,129	Use of the glycophorin A somatic mutation assay for rapid, unambiguous identification of Fanconi anemia homozygotes regardless of GPA genotype.	Am J Med Genet A	2005	https://conductscience.org/library/papers/15822129	PubMed
11,894,942	DNA repair dependent NAD+ metabolism is impaired in cells from patients with Fanconi's anemia.	EMBO J	1983	https://conductscience.org/library/papers/11894942	PubMed
7,450,765	Suppression of spontaneous and mitomycin C-induced chromosome aberrations in Fanconi's anemia by cell fusion with normal human fibroblasts.	Hum Genet	1980	https://conductscience.org/library/papers/7450765	PubMed
7,325,155	Functional deficiency of fibroblasts heterozygous for Bloom syndrome as specific manifestation of the primary defect.	Am J Hum Genet	1981	https://conductscience.org/library/papers/7325155	PubMed
7,250,972	Reduced uptake and incorporation of 3H-thymidine in Fanconi anemia fibroblasts.	Hum Genet	1981	https://conductscience.org/library/papers/7250972	PubMed
7,166,308	The cell cycle of lymphocytes in Fanconi anemia.	Hum Genet	1982	https://conductscience.org/library/papers/7166308	PubMed
7,004,875	Dna repair: pathways and defects.	Eur J Pediatr	1980	https://conductscience.org/library/papers/7004875	PubMed
6,992,563	Sister chromatid exchange analysis.	Am J Hum Genet	1980	https://conductscience.org/library/papers/6992563	PubMed
6,890,942	Cytogenetic toxicity of antitumor platinum compounds in Fanconi's anemia.	Hum Genet	1982	https://conductscience.org/library/papers/6890942	PubMed
6,885,053	Response of lymphocytes from Fanconi's anemia patients and their heterozygous relatives to 8-methoxy-psoralene in a cloning survival test system.	Hum Genet	1983	https://conductscience.org/library/papers/6885053	PubMed

1 to 10 of 21

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None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

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Data dates

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ClinicalTrials.govNo license stated
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iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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