Paper · 63363

In vivo BrdU-33258 Hoechst analysis of DNA replication kinetics and sister chromatid exchange formation in mouse somatic and meiotic cells.

Allen JW and 1 other. Chromosoma, 1976. Cited by 112 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. In vivo BrdU-33258 Hoechst analysis of DNA replication kinetics and sister chromatid exchange formation in mouse somatic and meiotic cells. Papers, record 63363. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/63363

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: In vivo BrdU-33258 Hoechst analysis of DNA replication kinetics and sister chromatid exchange formation in mouse somatic and meiotic cells.; PubMed
Journal: Chromosoma; PubMed
Year: 1976; PubMed
Publication types: Journal Article, Research Support, U.S. Gov't, P.H.S.; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/63363/; PubMed
DOI: https://doi.org/10.1007/bf00292841; PubMed
The journal: https://conductscience.org/library/journal-index/2985138R; PubMed
Citations, by iCite: 112; iCite
Relative citation ratio, by iCite: 4.04; iCite
Revised in PubMed: 2026-10-10; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Allen JW	J W
2	Latt SA	S A

Source PubMed

Topics16

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Benzimidazoles	Major topic
Bisbenzimidazole	Major topic
Bromodeoxyuridine	Major topic
Chromatids	Major topic
Crossing Over, Genetic	Major topic
DNA Replication	Major topic
Animals
Cyclophosphamide
Kinetics
Male
Meiosis
Mice
Mice, Inbred CBA
Mitomycins
Mitosis
Mutagens

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References35

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	4,128,545	Microfluorometric detection of deoxyribonucleic acid replication in human metaphase chromosomes.	Proc Natl Acad Sci U S A	1973	https://conductscience.org/library/papers/4128545	PubMed
2	53,130	A high resolution study of the DNA replication patterns of chinese hamster chromosomes using sister chromatid differential staining technique.	Chromosoma	1975	https://conductscience.org/library/papers/53130	PubMed
3	57,878	Fluorescence analysis of late DNA replication in mouse metaphase chromosomes using BUdR and 33258 Hoechst.	Exp Cell Res	1976	https://conductscience.org/library/papers/57878	PubMed
4	4,137,941	Spontaneous sister chromatid exchanges detected by a BUdR-labelling method.	Nature	1974	https://conductscience.org/library/papers/4137941	PubMed
5	4,477,047	Induction of a deoxycytidineless state in cultured mammalian cells by bromodeoxyuridine.	Cell	1974	https://conductscience.org/library/papers/4477047	PubMed
6	4,154,401	The formation and kinetics of reactive drug metabolites in mammals.	Mutat Res	1974	https://conductscience.org/library/papers/4154401	PubMed
7	1,176,135	Cytogenetic effects of cyclophosphamide on mouse spermatogonia.	Humangenetik	1975	https://conductscience.org/library/papers/1176135	PubMed
8	6,040,471	Timing of sex chromosome replication in somatic and germ-line cells of the mouse and the rat.	Cytogenetics	1967	https://conductscience.org/library/papers/6040471	PubMed
9	68,549	Fluorescence analysis of late DNA replication in human metaphase chromosomes.	Somatic Cell Genet	1975	https://conductscience.org/library/papers/68549	PubMed
10	4,141,299	Giemsa technique for the detection of sister chromatid exchanges.	Chromosoma	1974	https://conductscience.org/library/papers/4141299	PubMed

1 to 10 of 35

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Cited by21

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 112 citations.

PMID	Title	Journal	Year	In Papers	Source
32,744,506	ZCWPW1 is recruited to recombination hotspots by PRDM9 and is essential for meiotic double strand break repair.	Elife	2020	https://conductscience.org/library/papers/32744506	PubMed
25,565,522	Double-strand break repair on sex chromosomes: challenges during male meiotic prophase.	Cell Cycle	2015	https://conductscience.org/library/papers/25565522	PubMed
21,750,255	Genetic evidence that synaptonemal complex axial elements govern recombination pathway choice in mice.	Genetics	2011	https://conductscience.org/library/papers/21750255	PubMed
17,248,950	On the nature of sister-chromatid exchanges in 5-bromodeoxyuridine-substituted chromosomes.	Genetics	1979	https://conductscience.org/library/papers/17248950	PubMed
7,989,033	Mammalian meiotic recombination: a reexamination.	Hum Genet	1994	https://conductscience.org/library/papers/7989033	PubMed
7,587,590	Dynamic changes in Rad51 distribution on chromatin during meiosis in male and female vertebrates.	Chromosoma	1995	https://conductscience.org/library/papers/7587590	PubMed
7,189,706	Analysis of crossing over in mouse meiotic cells by BrdU labelling technique.	Chromosoma	1980	https://conductscience.org/library/papers/7189706	PubMed
7,072,718	A family study of spontaneous sister chromatid exchange frequency.	Am J Hum Genet	1982	https://conductscience.org/library/papers/7072718	PubMed
6,992,563	Sister chromatid exchange analysis.	Am J Hum Genet	1980	https://conductscience.org/library/papers/6992563	PubMed
6,975,199	Chromosome banding in Amphibia. VI. BrdU-replication patterns in anura and demonstration of XX/XY sex chromosomes in Rana esculenta.	Chromosoma	1981	https://conductscience.org/library/papers/6975199	PubMed

1 to 10 of 21

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Genes0

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None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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