Paper · 671586

Adenovirus type 2 early proteins synthesized in vitro and in vivo: identification in infected cells of the 38,000- to 50,000- molecular-weight protein encoded by the left end of the adenovirus type 2 genome.

Harter ML and 1 other. J Virol, 1978. Cited by 133 papers, by iCite.

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ConductScience Library. Adenovirus type 2 early proteins synthesized in vitro and in vivo: identification in infected cells of the 38,000- to 50,000- molecular-weight protein encoded by the left end of the adenovirus type 2 genome. Papers, record 671586. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/671586

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Adenovirus type 2 early proteins synthesized in vitro and in vivo: identification in infected cells of the 38,000- to 50,000- molecular-weight protein encoded by the left end of the adenovirus type 2 genome.; PubMed
Journal: J Virol; PubMed
Year: 1978; PubMed
Publication types: Journal Article, Research Support, U.S. Gov't, P.H.S.; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/671586/; PubMed
DOI: https://doi.org/10.1128/jvi.26.3.736-749.1978; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC525899/; PubMed
The journal: https://conductscience.org/library/journal-index/0113724; PubMed
Citations, by iCite: 133; iCite
Relative citation ratio, by iCite: 2.52; iCite
Revised in PubMed: 2020-07-24; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Harter ML	M L
2	Lewis JB	J B

Source PubMed

Topics9

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Adenoviruses, Human	Major topic
Peptide Biosynthesis	Major topic
Viral Proteins	Major topic
Electrophoresis, Polyacrylamide Gel
Genes, Viral
HeLa Cells
Molecular Weight
RNA, Messenger
RNA, Viral

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References20

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	198,139	A novel method to map transcripts: evidence for homology between an adenovirus mRNA and discrete multiple regions of the viral genome.	Cell	1977	https://conductscience.org/library/papers/198139	PubMed
2	320,200	Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.	J Biol Chem	1977	https://conductscience.org/library/papers/320200	PubMed
3	902,321	Two adenovirus mRNAs have a common 5' terminal leader sequence encoded at least 10 kb upstream from their main coding regions.	Cell	1977	https://conductscience.org/library/papers/902321	PubMed
4	902,319	Further mapping of late adenovirus genes by cell-free translation of RNA selected by hybridization to specific DNA fragments.	Cell	1977	https://conductscience.org/library/papers/902319	PubMed
5	890,740	A map of cytoplasmic RNA transcripts from lytic adenovirus type 2, determined by electron microscopy of RNA:DNA hybrids.	Cell	1977	https://conductscience.org/library/papers/890740	PubMed
6	837,446	The topography and transcription of the adenovirus genome.	Cell	1977	https://conductscience.org/library/papers/837446	PubMed
7	835,221	The isolation and identification of the adenovirus group C tumor antigens.	Virology	1977	https://conductscience.org/library/papers/835221	PubMed
8	1,004,548	Immunological identification of two adenovirus 2-induced early proteins possibly involved in cell transformation.	Nature	1976	https://conductscience.org/library/papers/1004548	PubMed
9	4,527,690	Cell-free synthesis of adenovirus 2 proteins programmed by fractionated messenger RNA: a comparison of polypeptide products and messenger RNA lengths.	Proc Natl Acad Sci U S A	1974	https://conductscience.org/library/papers/4527690	PubMed
10	167,021	Enhanced differential synthesis of proteins in a mammalian cell-free system by addition of polyamines.	J Biol Chem	1975	https://conductscience.org/library/papers/167021	PubMed

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Cited by49

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 133 citations.

PMID	Title	Journal	Year	In Papers	Source
11,753,665	Adenovirus E1A: remodelling the host cell, a life or death experience.	Oncogene	2001	https://conductscience.org/library/papers/11753665	PubMed
8,764,048	Importance of the Ser-132 phosphorylation site in cell transformation and apoptosis induced by the adenovirus type 5 E1A protein.	J Virol	1996	https://conductscience.org/library/papers/8764048	PubMed
8,627,766	Cyclin-dependent kinases phosphorylate the adenovirus E1A protein, enhancing its ability to bind pRb and disrupt pRb-E2F complexes.	J Virol	1996	https://conductscience.org/library/papers/8627766	PubMed
7,218,431	In vitro synthesis of adenovirus type 5 T antigens. II. Translation of virus-specific RNA from cells transformed by fragments of adenovirus type 5 DNA.	J Virol	1981	https://conductscience.org/library/papers/7218431	PubMed
7,176,021	Expression of adenovirus-2 early region 4: assignment of the early region 4 polypeptides to their respective mRNAs, using in vitro translation.	J Virol	1982	https://conductscience.org/library/papers/7176021	PubMed
7,143,568	Enhanced expression of adenovirus transforming proteins.	J Virol	1982	https://conductscience.org/library/papers/7143568	PubMed
7,097,863	Purification of a native membrane-associated adenovirus tumor antigen.	J Virol	1982	https://conductscience.org/library/papers/7097863	PubMed
7,086,956	Identification of adenovirus 2 early region 4 polypeptides by in vitro translation and tryptic peptide map analysis.	J Virol	1982	https://conductscience.org/library/papers/7086956	PubMed
7,045,392	Identification and purification of a protein encoded by the human adenovirus type 2 transforming region.	J Virol	1982	https://conductscience.org/library/papers/7045392	PubMed
6,985,482	Nucleotide sequence of adenovirus 2 DNA fragment encoding for the carboxylic region of the fiber protein and the entire E4 region.	Nucleic Acids Res	1981	https://conductscience.org/library/papers/6985482	PubMed

1 to 10 of 49

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None in this release.

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None in this release.

Data0

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ClinicalTrials.govNo license stated
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iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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