Paper · 67171

Immunosuppressive factor(s) extracted from lymphoid cells of nonresponder mice primed with L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) III. Immunochemical properties of the GAT-specific suppressive factor.

Theze J and 2 others. J Exp Med, 1977. Cited by 142 papers, by iCite.

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ConductScience Library. Immunosuppressive factor(s) extracted from lymphoid cells of nonresponder mice primed with L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) III. Immunochemical properties of the GAT-specific suppressive factor. Papers, record 67171. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/67171

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Immunosuppressive factor(s) extracted from lymphoid cells of nonresponder mice primed with L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) III. Immunochemical properties of the GAT-specific suppressive factor.; PubMed
Journal: J Exp Med; PubMed
Year: 1977; PubMed
Publication types: Journal Article, Research Support, U.S. Gov't, P.H.S.; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/67171/; PubMed
DOI: https://doi.org/10.1084/jem.145.4.839; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC2180626/; PubMed
The journal: https://conductscience.org/library/journal-index/2985109R; PubMed
Citations, by iCite: 142; iCite
Relative citation ratio, by iCite: 3.06; iCite
Revised in PubMed: 2021-12-03; PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Theze J	J
2	Kapp JA	J A
3	Benacerraf B	B

Source PubMed

Topics9

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Immunosuppression Therapy	Major topic
Peptides	Major topic
Proteins	Major topic
T-Lymphocytes	Major topic
Animals
Epitopes
Mice
Mice, Inbred DBA
Molecular Weight

Source PubMed

Grants0

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None in this release.

Trials0

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None in this release.

Comments and corrections0

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None in this release.

References13

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	1,084,407	Genetic control of specific immune suppression. IV. Responsiveness to the random copolymer L-glutamic acid50-L-tyrosine50 induced in BALB/c mice by cyclophosphamide.	J Exp Med	1976	https://conductscience.org/library/papers/1084407	PubMed
2	1,085,324	T-cell regulation of antibody responses: demonstration of allotype-specific helper T cells and their specific removal by suppressor T cells.	J Exp Med	1976	https://conductscience.org/library/papers/1085324	PubMed
3	1,085,339	Properties of the antigen-specific suppressive T-cell factor in the regulation of antibody response of the mouse. IV. Special subregion assignment of the gene(s) that codes for the suppressive T-cell factor in the H-2 histocompatibility complex.	J Exp Med	1976	https://conductscience.org/library/papers/1085339	PubMed
4	1,100,764	Antigen-specific T-cell factor in cell cooperation. Mapping within the I region of the H-2 complex and ability to cooperate across allogeneic barriers.	J Exp Med	1975	https://conductscience.org/library/papers/1100764	PubMed
5	1,101,468	Properties of primed suppressor T cells and their products.	Transplant Rev	1975	https://conductscience.org/library/papers/1101468	PubMed
6	1,104,746	Genetic control of specific immune suppression. I. Experimental conditions for the stimulation of suppressor cells by the copolymer L-glutamic acid50-L-tyrosine50 (GT) in nonresponder BALB/c mice.	J Exp Med	1975	https://conductscience.org/library/papers/1104746	PubMed
7	14,097,352	THE PREPARATION OF I-131-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITY.	Biochem J	1963	https://conductscience.org/library/papers/14097352	PubMed
8	4,137,682	Genetic control of immune responses in vitro. V. Stimulation of suppressor T cells in nonresponder mice by the terpolymer L-glutamic acid 60-L-alanine 30-L-tyrosine 10 (GAT).	J Exp Med	1974	https://conductscience.org/library/papers/4137682	PubMed
9	4,610,078	Antigen-specific T-cell factor in cell cooperation: physical properties and mapping in the left-hand (K) half of H-2.	J Exp Med	1974	https://conductscience.org/library/papers/4610078	PubMed
10	4,857,865	Genetic control of immune responses in vitro. 3. Tolerogenic properties of the terpolymer L-glutamic acid 60-L-alanine30-L-tyrosine10 (GAT) for spleen cells from nonresponder (H-2s and H-2q) mice.	J Exp Med	1974	https://conductscience.org/library/papers/4857865	PubMed

1 to 10 of 13

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Cited by49

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 142 citations.

PMID	Title	Journal	Year	In Papers	Source
6,978,487	Purification and characterization of a monoclonal T-cell suppressor factor specific for poly(LGlu60LAla30LTyr10).	Proc Natl Acad Sci U S A	1982	https://conductscience.org/library/papers/6978487	PubMed
6,966,320	Selective suppression of the major idiotypic component of an antihapten response by soluble T cell-derived factors with idiotypic or anti-idiotypic receptors.	J Exp Med	1980	https://conductscience.org/library/papers/6966320	PubMed
6,800,943	Genetic analysis of immune suppression. I. Gene complementation is required for suppression of antigen-specific proliferative responses by T-cell derived factors.	Immunogenetics	1981	https://conductscience.org/library/papers/6800943	PubMed
6,792,727	Helper and suppressor T cell factors.	Springer Semin Immunopathol	1980	https://conductscience.org/library/papers/6792727	PubMed
6,774,046	Two distinct antigen-specific suppressor factors induced by the oral administration of antigen.	J Exp Med	1980	https://conductscience.org/library/papers/6774046	PubMed
6,606,014	Antigen-specific suppressor T cell interactions. II. Characterization of two different types of suppressor T cell factors specific for L-glutamic acid50-L-tyrosine50 (GT) and L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT).	J Exp Med	1983	https://conductscience.org/library/papers/6606014	PubMed
6,454,757	Haplotype-specific suppression of antibody responses in vitro. II. Suppressor factor produced by T cells and T cell hybridomas from mice treated as neonates with semiallogeneic spleen cells.	J Exp Med	1981	https://conductscience.org/library/papers/6454757	PubMed
6,447,186	Suppression of antibody and T cell proliferative responses to L-glutamic acid60-L-alanine30-L-tyrosine10 by a specific monoclonal T cell factor.	J Exp Med	1980	https://conductscience.org/library/papers/6447186	PubMed
6,416,834	Analysis of antibody diversity: V-D-J mRNA nucleotide sequence of four anti-GAT monoclonal antibodies. A paucigene system using alternate D-J recombinations to generate functionally similar hypervariable regions.	EMBO J	1983	https://conductscience.org/library/papers/6416834	PubMed
6,378,461	Diffusible suppressor factor from splenic macrophages in murine plasmacytoma.	Clin Exp Immunol	1984	https://conductscience.org/library/papers/6378461	PubMed

1 to 10 of 49

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
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PubTator 3Public domain
UniProtCC BY 4.0

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NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
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PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

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