ConductScience.org, home

Paper67172

The monoclonal anti-phosphorylcholine antibody response in several murine strains: genetic implications of a diverse repertoire.

Gearhart PJ and 2 others. J Exp Med, 1977. Cited by 57 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Download JSON
Cite this record

ConductScience Library. The monoclonal anti-phosphorylcholine antibody response in several murine strains: genetic implications of a diverse repertoire. Papers, record 67172. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/67172

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
The monoclonal anti-phosphorylcholine antibody response in several murine strains: genetic implications of a diverse repertoire.
PubMed
Journal
J Exp Med
PubMed
Year
1977
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
57
iCite
Relative citation ratio, by iCite
0.98
iCite
Revised in PubMed
2019-05-08
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Gearhart PJP J
2Sigal NHN H
3Klinman NRN R

Source PubMed

Topics10

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Antibody FormationMajor topic
Antibody SpecificityMajor topic
CholineMajor topic
Immunoglobulin AllotypesMajor topic
PhosphorylcholineMajor topic
Animals
Binding Sites, Antibody
Epitopes
Genes
Mice

Source PubMed

References27

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
11,078,833The frequency of phosphorylcholine-specific B cells in conventional and germfree BALB/C mice.J Immunol1975https://conductscience.org/library/papers/1078833PubMed
21,080,568Production of antibodies of identical idiotype but diverse immunoglobulin classes by cells derived from a single stimulated B cell.Proc Natl Acad Sci U S A1975https://conductscience.org/library/papers/1080568PubMed
311,993,341The analysis of the monoclonal immune response to influenza virus. I. Production of monoclonal anti-viral antibodies in vitro.Eur J Immunol1975https://conductscience.org/library/papers/11993341PubMed
44,117,282Inheritance of an idiotype associated with the immune response of inbred mice to phosphorylcholine.Eur J Immunol1972https://conductscience.org/library/papers/4117282PubMed
54,119,224Immunochemical analysis of the cross-reacting idiotypes of mouse myeloma proteins with anti-dextran activity and normal anti-dextran antibody.Proc Natl Acad Sci U S A1973https://conductscience.org/library/papers/4119224PubMed
64,120,094Evidence for the linkage of the IGC H locus to a gene controlling the idiotypic specificity of anti-p-azophenylarsonate antibodies in strain A mice.J Exp Med1973https://conductscience.org/library/papers/4120094PubMed
74,128,448Clonal nature of the immune response to phosphorylcholine. I. Specificity, class, and idiotype of phosphorylcholine-binding receptors on lymphoid cells.J Exp Med1974https://conductscience.org/library/papers/4128448PubMed
84,131,516Genetics of a new IgVH (T15 idiotype) marker in the mouse regulating natural antibody to phosphorylcholine.J Exp Med1974https://conductscience.org/library/papers/4131516PubMed
94,137,581Clonal nature of the immune response to phosphorylcholine. IV. Idiotypic uniformity of binding site-associated antigenic determinants among mouse antiphosphorylcholine antibodies.J Exp Med1974https://conductscience.org/library/papers/4137581PubMed
104,137,613Diversity of antibodies to cross-reacting nitrophenyl haptens in inbred mice.Eur J Immunol1974https://conductscience.org/library/papers/4137613PubMed
114,190,693Affinity labeling of a mouse myeloma protein which binds nitrophenyl ligands. Kinetics of labeling and isolation of a labeled peptide.Biochemistry1970https://conductscience.org/library/papers/4190693PubMed
124,403,565Specific suppression of the antibody response by antibodies to receptors.Proc Natl Acad Sci U S A1972https://conductscience.org/library/papers/4403565PubMed
134,546,808Frequency of hapten-specific B cells in neonatal and adult murine spleens.Eur J Immunol1974https://conductscience.org/library/papers/4546808PubMed
1446,246Specific isolation and characterization of antibody directed to binding site antigenic determinants.J Immunol1975https://conductscience.org/library/papers/46246PubMed
1546,913Heterogeneity of the BALB/c antiphosphorylcholine antibody response at the precursor cell level.J Exp Med1975https://conductscience.org/library/papers/46913PubMed
164,717,931Nature of anti-hapten antibodies arising after immune suppression of a set of cross-raactive idiotypic specificities.Eur J Immunol1973https://conductscience.org/library/papers/4717931PubMed
174,736,831Monoclonal production of both IgM and IgG1 antihapten antibody.J Exp Med1973https://conductscience.org/library/papers/4736831PubMed
1847,894Clonal nature of the immune response to phosphorylcholine (PC). V. Cross-idiotypic specificity among heavy chains of murine anti-PC antibodies and PC-binding myeloma proteins.J Exp Med1975https://conductscience.org/library/papers/47894PubMed
195,059,886Affinity labeling of a phosphorylcholine binding mouse myeloma protein.Biochemistry1972https://conductscience.org/library/papers/5059886PubMed
205,289,884Association of H-2 types with genetic control of immune responsiveness to IgA allotypes in the mouse.Proc Natl Acad Sci U S A1971https://conductscience.org/library/papers/5289884PubMed

See all 27 references

Cited by15

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 57 citations.

PMIDTitleJournalYearIn PapersSource
33,782,153Sialic Acid Protects Nontypeable Haemophilus influenzae from Natural IgM and Promotes Survival in Murine Respiratory Tract.Infect Immun2021https://conductscience.org/library/papers/33782153PubMed
26,194,752Restricted, canonical, stereotyped and convergent immunoglobulin responses.Philos Trans R Soc Lond B Biol Sci2015https://conductscience.org/library/papers/26194752PubMed
24,760,047Selection of apoptotic cell specific human antibodies from adult bone marrow.PLoS One2014https://conductscience.org/library/papers/24760047PubMed
22,566,947Protective Roles of Natural IgM Antibodies.Front Immunol2012https://conductscience.org/library/papers/22566947PubMed
19,414,754IgM antibodies to apoptosis-associated determinants recruit C1q and enhance dendritic cell phagocytosis of apoptotic cells.J Immunol2009https://conductscience.org/library/papers/19414754PubMed
10,811,914Highly reduced protection against Streptococcus pneumoniae after deletion of a single heavy chain gene in mouse.Proc Natl Acad Sci U S A2000https://conductscience.org/library/papers/10811914PubMed
7,299,349Anti-phosphocholine hybridoma antibodies. II. Functional analysis of binding sites within three antibody families.J Exp Med1981https://conductscience.org/library/papers/7299349PubMed
6,787,165Anti-phosphocholine hybridoma antibodies. I. Direct evidence for three distinct families of antibodies in the murine response.J Exp Med1981https://conductscience.org/library/papers/6787165PubMed
6,606,013Role of variable region gene expression and environmental selection in determining the antiphosphorylcholine B cell repertoire.J Exp Med1983https://conductscience.org/library/papers/6606013PubMed
6,601,176Genetic and temporal control of neonatal antibody expression.J Exp Med1983https://conductscience.org/library/papers/6601176PubMed
6,207,261
Complete amino acid sequence of heavy chain variable regions derived from two monoclonal anti-p-azophenylarsonate antibodies of BALB/c mice expressing the major cross-reactive idiotype of the A/J strain.
J Exp Med1984https://conductscience.org/library/papers/6207261PubMed
416,167The diversity of the influenza-specific primary B-cell repertoire in BALB/c mice.J Exp Med1978https://conductscience.org/library/papers/416167PubMed
302,315Expression of phosphorylcholine-specific B cells during murine development.J Exp Med1977https://conductscience.org/library/papers/302315PubMed
301,547Novel idiotypic and antigen-binding characteristics in two anti-dinitrophenyl monoclonal antibodies.J Exp Med1977https://conductscience.org/library/papers/301547PubMed
75,230Differential expression of an equivalent clonotype among BALB/c and C57BL/6 mice.J Exp Med1978https://conductscience.org/library/papers/75230PubMed

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this paper from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/papers/v1/67172

GET https://conductscience.org/api/papers/v1/67172/references?page=2