Paper · 69002

Enrichment of antigen-specific B lymphocytes by the direct removal of B cells not bearing specificity for the antigen.

Walker SM and 2 others. J Exp Med, 1977. Cited by 19 papers, by iCite.

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ConductScience Library. Enrichment of antigen-specific B lymphocytes by the direct removal of B cells not bearing specificity for the antigen. Papers, record 69002. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/69002

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Enrichment of antigen-specific B lymphocytes by the direct removal of B cells not bearing specificity for the antigen.; PubMed
Journal: J Exp Med; PubMed
Year: 1977; PubMed
Publication types: Journal Article, Research Support, U.S. Gov't, P.H.S.; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/69002/; PubMed
DOI: https://doi.org/10.1084/jem.146.2.445; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC2180762/; PubMed
The journal: https://conductscience.org/library/journal-index/2985109R; PubMed
Citations, by iCite: 19; iCite
Relative citation ratio, by iCite: 0.5; iCite
Revised in PubMed: 2019-05-08; PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Walker SM	S M
2	Meinke GC	G C
3	Weigle WO	W O

Source PubMed

Topics15

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
B-Lymphocytes	Major topic
Epitopes	Major topic
Animals
Cell Separation
Erythrocytes
Hemolytic Plaque Technique
Immunoglobulins
Immunologic Techniques
Male
Mice
Mice, Inbred A
Sheep
Spleen
Turkeys
gamma-Globulins

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References28

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	1,084,410	Antifluorescein affinity columns. Isolation and immunocompetence of lymphocytes that bind fluoresceinated antigens in vivo or in vitro.	J Exp Med	1976	https://conductscience.org/library/papers/1084410	PubMed
2	165,257	Separation of antigen-specific lymphocytes. II. Enrichment of hapten-specific antibody-forming cell precursors.	J Exp Med	1975	https://conductscience.org/library/papers/165257	PubMed
3	167,077	A procedure for removing red cells and dead cells from lymphoid cell suspensions.	J Immunol Methods	1975	https://conductscience.org/library/papers/167077	PubMed
4	4,114,858	Demonstration that antigen-binding cells are precursors of antibody-producing cells after purification with a fluorescence-activated cell sorter.	Proc Natl Acad Sci U S A	1972	https://conductscience.org/library/papers/4114858	PubMed
5	4,119,591	Fate of antigen-binding cells in unresponsive and immune mice.	J Exp Med	1973	https://conductscience.org/library/papers/4119591	PubMed
6	4,119,592	2,4-Dinitrophenyl receptors on mouse thymus and spleen cells.	J Exp Med	1973	https://conductscience.org/library/papers/4119592	PubMed
7	4,120,897	Critical role of determinant presentation in the induction of specific responses in immunocompetent lymphocytes.	J Exp Med	1973	https://conductscience.org/library/papers/4120897	PubMed
8	4,137,510	A new, simple method for the preparation of lymphocytes bearing specific receptors.	Eur J Immunol	1974	https://conductscience.org/library/papers/4137510	PubMed
9	4,139,227	Isolation of antigen-binding cells from unprimed mice: demonstration of antibody-forming cell precursor activity and correlation between precursor and secreted antibody avidities.	J Exp Med	1974	https://conductscience.org/library/papers/4139227	PubMed
10	4,170,425	A modification of the hemolytic plaque assay for use with protein antigens.	J Immunol	1968	https://conductscience.org/library/papers/4170425	PubMed

1 to 10 of 28

See all 28 references

Cited by3

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 19 citations.

PMID	Title	Journal	Year	In Papers	Source
7,393,313	Resistance to Nocardia brasiliensis infection in mice immunized with either Nocardia or BCG.	Mycopathologia	1980	https://conductscience.org/library/papers/7393313	PubMed
6,166,703	In vitro tolerance induction of primed, IgD-negative murine spleen cells.	J Exp Med	1981	https://conductscience.org/library/papers/6166703	PubMed
316,856	In vitro anamnestic immune responses and modulating factors.	Mol Cell Biochem	1979	https://conductscience.org/library/papers/316856	PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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