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Paper6957856

Regulated expression of human interferon beta 1 gene after transduction into cultured mouse and rabbit cells.

Canaani D and 1 other. Proc Natl Acad Sci U S A, 1982. Cited by 75 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Regulated expression of human interferon beta 1 gene after transduction into cultured mouse and rabbit cells. Papers, record 6957856. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/6957856

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Regulated expression of human interferon beta 1 gene after transduction into cultured mouse and rabbit cells.
PubMed
Journal
Proc Natl Acad Sci U S A
PubMed
Year
1982
PubMed
Publication types
Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
75
iCite
Relative citation ratio, by iCite
1.62
iCite
Revised in PubMed
2019-12-10
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Canaani DD
2Berg PP

Source PubMed

Topics17

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
GenesMajor topic
Interferon Type IMajor topic
Transduction, GeneticMajor topic
Animals
Cells, Cultured
Cloning, Molecular
DNA, Superhelical
Fibroblasts
Humans
Kidney
L Cells
Male
Mice
Plasmids
RNA, Messenger
Rabbits
Skin

Source PubMed

Grants2

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
GM-13235NIGMS NIH HHSUnited StatesR01GM013235PubMed and NIHNIH RePORTER
R37GM013235NIHNIH RePORTER

References31

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
16,159,635Synthesis of new proteins associated with the induction of interferon in human fibroblast cells.Proc Natl Acad Sci U S A1980https://conductscience.org/library/papers/6159635PubMed
26,174,942Inducer-responsive expression of the cloned human interferon beta 1 gene introduced into cultured mouse cells.Nucleic Acids Res1982https://conductscience.org/library/papers/6174942PubMed
3881,736Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.J Mol Biol1977https://conductscience.org/library/papers/881736PubMed
4183,602Steroid receptors: elements for modulation of eukaryotic transcription.Annu Rev Biochem1976https://conductscience.org/library/papers/183602PubMed
56,267,479Inhibition of SV40 replication in simian cells by specific pBR322 DNA sequences.Nature1981https://conductscience.org/library/papers/6267479PubMed
66,164,984Human fibroblast interferon gene lacks introns.Nucleic Acids Res1981https://conductscience.org/library/papers/6164984PubMed
76,169,589Nucleotide sequence of the chromosomal gene for human fibroblast (beta 1) interferon and of the flanking regions.Gene1981https://conductscience.org/library/papers/6169589PubMed
8222,468Transformation of mammalian cells with genes from procaryotes and eucaryotes.Cell1979https://conductscience.org/library/papers/222468PubMed
9225,559Regulation of simian virus 40 transcription: sensitive analysis of the RNA species present early in infections by virus or viral DNA.J Virol1979https://conductscience.org/library/papers/225559PubMed
104,291,934Selective extraction of polyoma DNA from infected mouse cell cultures.J Mol Biol1967https://conductscience.org/library/papers/4291934PubMed
114,209,831Sequential gene activation by ecdysone in polytene chromosomes of Drosophila melanogaster. II. The effects of inhibitors of protein synthesis.Dev Biol1974https://conductscience.org/library/papers/4209831PubMed
126,174,973Analysis of interferon mRNA in human fibroblast cells induced to produce interferon.Proc Natl Acad Sci U S A1981https://conductscience.org/library/papers/6174973PubMed
136,159,580The complete amino acid sequence of human fibroblast interferon as deduced using synthetic oligodeoxyribonucleotide primers of reverse transcriptase.Nucleic Acids Res1980https://conductscience.org/library/papers/6159580PubMed
14206,891Spliced early mRNAs of simian virus 40.Proc Natl Acad Sci U S A1978https://conductscience.org/library/papers/206891PubMed
156,251,549Expression of a bacterial gene in mammalian cells.Science1980https://conductscience.org/library/papers/6251549PubMed
1616,593,086Structure of a chromosomal gene for human interferon beta.Proc Natl Acad Sci U S A1981https://conductscience.org/library/papers/16593086PubMed
17212,202Dexamethasone-mediated induction of mouse mammary tumor virus RNA: a system for studying glucocorticoid action.Cell1975https://conductscience.org/library/papers/212202PubMed
181,195,397Detection of specific sequences among DNA fragments separated by gel electrophoresis.J Mol Biol1975https://conductscience.org/library/papers/1195397PubMed
196,168,999The structure of a thirty-six kilobase region of the human chromosome including the fibroblast interferon gene IFN-beta.Nucleic Acids Res1981https://conductscience.org/library/papers/6168999PubMed
20219,218Mutational alterations within the simian virus 40 leader segment generate altered 16S and 19S mRNA's.J Virol1979https://conductscience.org/library/papers/219218PubMed

See all 31 references

Cited by26

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 75 citations.

PMIDTitleJournalYearIn PapersSource
29,738,459Functional Analysis of the Promoter Region of Japanese Flounder (Paralichthys olivaceus) β-actin Gene: A Useful Tool for Gene Research in Marine Fish.Int J Mol Sci2018https://conductscience.org/library/papers/29738459PubMed
11,894,945Sequences involved in the regulated expression of the human interferon-beta1 gene in recombinant SV40 DNA vectors replicating in monkey cells.EMBO J1983https://conductscience.org/library/papers/11894945PubMed
8,262,551Intermediate- and high-affinity interleukin-2 receptors expressed in an IL-4-dependent T-cell line induce different signals.Immunology1993https://conductscience.org/library/papers/8262551PubMed
7,862,536Establishment of an autocatalytic conditional mammalian system for expression of stringently regulated genes.Nucleic Acids Res1995https://conductscience.org/library/papers/7862536PubMed
7,770,532Nucleotide sequence of a cDNA encoding mitochondrial malate dehydrogenase from Eucalyptus.Plant Physiol1995https://conductscience.org/library/papers/7770532PubMed
6,856,471Human fibroblast interferon RNA transcripts of different sizes in poly(I).poly(C) induced cells.Nucleic Acids Res1983https://conductscience.org/library/papers/6856471PubMed
6,700,582Inducible expression of amplified human beta interferon genes in CHO cells.Mol Cell Biol1984https://conductscience.org/library/papers/6700582PubMed
6,427,755Differential expression of human interferon genes.Nucleic Acids Res1984https://conductscience.org/library/papers/6427755PubMed
6,406,983In vivo incorporation of Drosophila H2a histone into mammalian chromatin.Nucleic Acids Res1983https://conductscience.org/library/papers/6406983PubMed
6,330,533Enhanced transformation of human cells by UV-irradiated pSV2 plasmids.Mol Cell Biol1984https://conductscience.org/library/papers/6330533PubMed
6,328,483Polypeptide hormone regulation of gene transcription: specific 5' genomic sequences are required for epidermal growth factor and phorbol ester regulation of prolactin gene expression.Proc Natl Acad Sci U S A1984https://conductscience.org/library/papers/6328483PubMed
6,318,086Production of human beta interferon in insect cells infected with a baculovirus expression vector.Mol Cell Biol1983https://conductscience.org/library/papers/6318086PubMed
6,316,279Expression of cloned immunoglobulin genes introduced into mouse L cells.Nucleic Acids Res1983https://conductscience.org/library/papers/6316279PubMed
6,310,498The 5'-flanking sequence of human interferon-beta 1 gene is responsible for viral induction of transcription.Nucleic Acids Res1983https://conductscience.org/library/papers/6310498PubMed
6,306,597The gene S promoter of hepatitis B virus confers constitutive gene expression.Nucleic Acids Res1983https://conductscience.org/library/papers/6306597PubMed
6,306,284Cycloheximide induces expression of the human interferon beta 1 gene in mouse cells transformed by bovine papillomavirus-interferon beta 1 recombinants.J Virol1983https://conductscience.org/library/papers/6306284PubMed
6,091,048A human IFN-beta 1 gene deleted of promoter sequences upstream from the TATA box is controlled post-transcriptionally by dsRNA.Nucleic Acids Res1984https://conductscience.org/library/papers/6091048PubMed
3,785,197Transcriptional and posttranscriptional regulation of exogenous human beta interferon gene in simian cells defective in interferon synthesis.Mol Cell Biol1986https://conductscience.org/library/papers/3785197PubMed
3,773,893Activation of the human beta-interferon gene requires an interferon-inducible factor.Mol Cell Biol1986https://conductscience.org/library/papers/3773893PubMed
3,480,511Complementation of the UV-sensitive phenotype of a xeroderma pigmentosum human cell line by transfection with a cDNA clone library.Proc Natl Acad Sci U S A1987https://conductscience.org/library/papers/3480511PubMed

See all 26 cited by

Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn Genes
IFNB13,456PubTator's text mininghttps://conductscience.org/library/genes/3456

Source NCBI Gene

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Trials
  • Comments and corrections
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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