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Paper6970643

Naturally occurring human antibodies to the F(ab')2 portion of IgG.

Nasu H and 3 others. Clin Exp Immunol, 1980. Cited by 114 papers, by iCite.

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ConductScience Library. Naturally occurring human antibodies to the F(ab')2 portion of IgG. Papers, record 6970643. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/6970643

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Naturally occurring human antibodies to the F(ab')2 portion of IgG.
PubMed
Journal
Clin Exp Immunol
PubMed
Year
1980
PubMed
Publication types
Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
114
iCite
Relative citation ratio, by iCite
3.86
iCite
Revised in PubMed
2018-11-13
PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Nasu HH
2Chia DSD S
3Knutson DWD W
4Barnett EVE V

Source PubMed

Topics9

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Antibodies, Anti-IdiotypicMajor topic
Immunoglobulin Fab FragmentsMajor topic
Immunoglobulin GMajor topic
Arthritis, Rheumatoid
Communicable Diseases
Humans
Immunity, Innate
Radioimmunoassay
Rheumatic Diseases

Source PubMed

Grants1

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated by
AG00790-02NIA NIH HHSUnited StatesPubMed

Source PubMed

References26

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
15,432,796Protein purification by affinity chromatography. Derivatizations of agarose and polyacrylamide beads.J Biol Chem1970https://conductscience.org/library/papers/5432796PubMed
265,297Complementary idiotypy in the regulation of the immune response.Fed Proc1977https://conductscience.org/library/papers/65297PubMed
34,142,565Towards a network theory of the immune system.Ann Immunol (Paris)1974https://conductscience.org/library/papers/4142565PubMed
413,945,475Reduction of gamma-globulins.Arch Biochem Biophys1962https://conductscience.org/library/papers/13945475PubMed
6314,964Characterization and measurement of anti-IgG antibodies in human sera by radioimmunoassay (RIA).J Immunol Methods1979https://conductscience.org/library/papers/314964PubMed
74,113,485Specific inhibition of plaque formation to phosphorylcholine by antibody against antibody.Science1972https://conductscience.org/library/papers/4113485PubMed
814,335,252GM(F)--A DETERMINANT OF HUMAN GAMMA-GLOBULIN.Vox Sang1965https://conductscience.org/library/papers/14335252PubMed
94,403,565Specific suppression of the antibody response by antibodies to receptors.Proc Natl Acad Sci U S A1972https://conductscience.org/library/papers/4403565PubMed
1047,218Hypervariable regions, idiotypy, and the antibody-combining site.Adv Immunol1975https://conductscience.org/library/papers/47218PubMed
115,314,108The influence of infection on titres of antiglobulin antibodies.Clin Exp Immunol1971https://conductscience.org/library/papers/5314108PubMed
12437,828Isolation of stable aggregates of IgG by zonal ultracentrifugation in sucrose gradients containing albumin.Immunol Commun1979https://conductscience.org/library/papers/437828PubMed
135,138,821The first human example of anti-Gm(17): Gm(z).Vox Sang1971https://conductscience.org/library/papers/5138821PubMed
144,108,426Biological effects of anti-immunoglobulins: evidence for immunoglobulin receptors on 'T' and 'B' lymphocytes.Transplant Rev1970https://conductscience.org/library/papers/4108426PubMed
1514,434,282The hydrolysis of rabbit y-globulin and antibodies with crystalline papain.Biochem J1959https://conductscience.org/library/papers/14434282PubMed
1614,450,081Preparation of iodine-131 labelled human growth hormone of high specific activity.Nature1962https://conductscience.org/library/papers/14450081PubMed
17366,731Effects of anti-immunoglobulin sera on B lymphocyte functions.Scand J Immunol1978https://conductscience.org/library/papers/366731PubMed
184,162,019Heterogeneity of anti-gamma-globulin factors detected by pepsin-digested human gamma G-globulin.Acta Pathol Microbiol Scand1966https://conductscience.org/library/papers/4162019PubMed
1913,701,434Structural units of human 7S gamma globulin.J Clin Invest1960https://conductscience.org/library/papers/13701434PubMed
201,082,458In vitro response of subpopulations of human lymphocytes. II. DNA synthesis induced by anti-immunoglobulin antibodies.J Immunol1976https://conductscience.org/library/papers/1082458PubMed
214,976,105Immunochemical and serological studies of enzymaatically fragmented human IgG globulins. II. Hydrolysis with subtilisin, elastase, trypsin, and chymotrypsin.Immunochemistry1969https://conductscience.org/library/papers/4976105PubMed

See all 26 references

Cited by30

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 114 citations.

PMIDTitleJournalYearIn PapersSource
31,601,945Characterization of canine anti-mouse antibodies highlights that multiple strategies are needed to combat immunoassay interference.Sci Rep2019https://conductscience.org/library/papers/31601945PubMed
31,099,718Investigation of pre-existing reactivity to biotherapeutics can uncover potential immunogenic epitopes and predict immunogenicity risk.MAbs2019https://conductscience.org/library/papers/31099718PubMed
20,739,749Why antibodies disobey the Hippocratic Oath and end up doing harm: a new clue.J Clin Invest2010https://conductscience.org/library/papers/20739749PubMed
10,583,608Histidine-rich glycoprotein prevents the formation of insoluble immune complexes by rheumatoid factor.Immunology1999https://conductscience.org/library/papers/10583608PubMed
9,649,575Anti-idiotypic antibodies prevent the serologic detection of antiribosomal P autoantibodies in healthy adults.J Clin Invest1998https://conductscience.org/library/papers/9649575PubMed
9,227,858Yeast killer systems.Clin Microbiol Rev1997https://conductscience.org/library/papers/9227858PubMed
9,050,877The antigen-binding domain of a human IgG-anti-F(ab')2 autoantibody.Proc Natl Acad Sci U S A1997https://conductscience.org/library/papers/9050877PubMed
8,394,233
Suppression of anti-erythrocyte autoantibody-producing B cells by a physiological IgG-anti-F(ab')2 antibody and escape from suppression by tumour transformation; a model relevant for the pathogenesis of autoimmune haemolytic anaemia.
Clin Exp Immunol1993https://conductscience.org/library/papers/8394233PubMed
8,252,808Induction of an anti-Fab, anti-DNA and anti-RNA polymerase I autoantibody response network in rabbits immunized with SLE anti-DNA antibody.Clin Exp Immunol1993https://conductscience.org/library/papers/8252808PubMed
8,235,289Differences in anti-Fab antibodies in adult and late onset rheumatoid arthritis.Rheumatol Int1993https://conductscience.org/library/papers/8235289PubMed
7,923,885Platelet surface IgG in patients receiving infusions of Fab fragments of a chimaeric monoclonal antibody to glycoprotein IIb-IIIa.Clin Exp Immunol1994https://conductscience.org/library/papers/7923885PubMed
7,040,177Liver membrane antibodies in alcoholic liver disease: 1. prevalence and immunoglobulin class.Gut1982https://conductscience.org/library/papers/7040177PubMed
7,021,589Method for avoiding false-positive results occurring in immunoglobulin M enzyme-linked immunosorbent assays due to presence of both rheumatoid factor and antinuclear antibodies.J Clin Microbiol1981https://conductscience.org/library/papers/7021589PubMed
6,607,933Human auto-antiidiotypes regulating T cell-mediated reactivity to tetanus toxoid.J Clin Invest1984https://conductscience.org/library/papers/6607933PubMed
6,377,539Suppression of autoimmune diseases with anti-idiotypic antibodies: murine lupus nephritis as a model.Springer Semin Immunopathol1984https://conductscience.org/library/papers/6377539PubMed
6,355,197Liver membrane antibodies in alcoholic liver disease. II. Antibodies to ethanol-altered hepatocytes.J Clin Pathol1983https://conductscience.org/library/papers/6355197PubMed
6,178,755Peripheral T lymphocytes from rheumatoid arthritis patients recognize determinants on light chains and/or Fab fragments of immunoglobulin G.J Clin Invest1982https://conductscience.org/library/papers/6178755PubMed
3,928,684Anti-Fab antibodies in humans. Predominance of minor immunoglobulin G subclasses in rheumatoid arthritis.J Clin Invest1985https://conductscience.org/library/papers/3928684PubMed
3,874,025Family distribution of anti-F(ab')2 antibodies in relatives of patients with systemic lupus erythematosus.Clin Exp Immunol1985https://conductscience.org/library/papers/3874025PubMed
3,500,815Anti-idiotypic antibody against anti-DNA in sera of laboratory personnel exposed to lupus sera or nucleic acids.Clin Exp Immunol1987https://conductscience.org/library/papers/3500815PubMed

See all 30 cited by

Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn Genes
FANCB2,187PubTator's text mininghttps://conductscience.org/library/genes/2187

Source NCBI Gene

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

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  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
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  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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