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Paper · 6972730

Antibacterial activity of 2',3'-dideoxyadenosine in vivo and in vitro.

Beskid G and 6 others. Antimicrob Agents Chemother, 1981. Cited by 11 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Antibacterial activity of 2',3'-dideoxyadenosine in vivo and in vitro. Papers, record 6972730. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/6972730

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Antibacterial activity of 2',3'-dideoxyadenosine in vivo and in vitro.
PubMed
Journal
Antimicrob Agents Chemother
PubMed
Year
1981
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
11
iCite
Relative citation ratio, by iCite
0.38
iCite
Revised in PubMed
2021-05-26
PubMed

Authors7

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Beskid GG
2Eskin BB
3Cleeland RR
4Siebelist JJ
5Cappetta AA
6Hill ADA D
7Geiger RHR H

Source PubMed

Topics11

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Anti-Bacterial AgentsMajor topic
BacteriaMajor topic
Bacterial InfectionsMajor topic
DeoxyadenosinesMajor topic
Animals
DNA
Dideoxyadenosine
Drug Synergism
Lethal Dose 50
Mice
Structure-Activity Relationship

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References15

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
1440,966The DNA polymerases associated with the adenovirus type 2 replication complex: effect of 2'-3'-dideoxythymidine-5'-triphosphate on viral DNA synthesis.Nucleic Acids Res1979https://conductscience.org/library/papers/440966PubMed
214,438,703A simple membrane fractionation method for determining the distribution of radioactivity in chemical fractions of Bacillus cereus.Biochim Biophys Acta1960https://conductscience.org/library/papers/14438703PubMed
34,262,082DNA synthesis in nucleotide-permeable Escherichia coli cells. The effects of nucleotide analogues on DNA synthesis.Eur J Biochem1972https://conductscience.org/library/papers/4262082PubMed
41,170,887DNA chain termination by 2',3'-dideoxythymidine in replicating mammalian cells.Biochemistry1975https://conductscience.org/library/papers/1170887PubMed
54,225,176Nonclassical antimetabolites. XXV. Inhibitors of thymidine kinase. I. A new spectrophotometric assay. Inhibition by nucleoside derivatives.J Med Chem1966https://conductscience.org/library/papers/4225176PubMed
65,332,078Polymer synthesis in killed bacteria: lethality of 2',3'-dideoxyadenosine.J Bacteriol1966https://conductscience.org/library/papers/5332078PubMed
71,079,475Two approaches that increase the activity of analogs of adenine nucleosides in animal cells.Cancer Res1975https://conductscience.org/library/papers/1079475PubMed
86,048,501The role of the 5'-hydroxyl group of adenosine in determining substrate specificity for adenosine deaminase.J Med Chem1967https://conductscience.org/library/papers/6048501PubMed
916,557,848Effect of mg and ethylenediaminetetraacetate on the in vitro activity of coumermycin a(1) and novobiocin against gram-negative bacteria.Infect Immun1970https://conductscience.org/library/papers/16557848PubMed
10320,756Contrasting effects of 2',3'-dideoxyadenosine on two steps in the replication of phi X 174 DNA in Escherichia coli.Virology1977https://conductscience.org/library/papers/320756PubMed

Cited by7

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 11 citations.

PMIDTitleJournalYearIn PapersSource
40,757,243Deoxynucleosides as promising antimicrobial agents against foodborne pathogens and their applications in food and contact material surfaces.Curr Res Food Sci2025https://conductscience.org/library/papers/40757243PubMed
36,525,240Potential in vitro action of an adenosine analog and synergism with penicillin against Corynebacterium pseudotuberculosis.Braz J Microbiol2023https://conductscience.org/library/papers/36525240PubMed
33,441,754Impact of long-term antiretroviral therapy on gut and oral microbiotas in HIV-1-infected patients.Sci Rep2021https://conductscience.org/library/papers/33441754PubMed
22,696,237
Machine learning analysis of the relationship between changes in immunological parameters and changes in resistance to Listeria monocytogenes: a new approach for risk assessment and systems immunology.
Toxicol Sci2012https://conductscience.org/library/papers/22696237PubMed
8,431,005In vitro activities of nucleoside analog antiviral agents against salmonellae.Antimicrob Agents Chemother1993https://conductscience.org/library/papers/8431005PubMed
2,118,327Induction of the SOS response in Escherichia coli by azidothymidine and dideoxynucleosides.Antimicrob Agents Chemother1990https://conductscience.org/library/papers/2118327PubMed
1,379,914Didanosine. A review of its antiviral activity, pharmacokinetic properties and therapeutic potential in human immunodeficiency virus infection.Drugs1992https://conductscience.org/library/papers/1379914PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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