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Paper6974029

Distribution of P1- and P2-purinoceptors in the guinea-pig and frog heart.

Burnstock G and 1 other. Br J Pharmacol, 1981. Cited by 81 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Distribution of P1- and P2-purinoceptors in the guinea-pig and frog heart. Papers, record 6974029. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/6974029

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Distribution of P1- and P2-purinoceptors in the guinea-pig and frog heart.
PubMed
Journal
Br J Pharmacol
PubMed
Year
1981
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
81
iCite
Relative citation ratio, by iCite
2.98
iCite
Revised in PubMed
2019-05-11
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Burnstock GG
2Meghji PP

Source PubMed

Topics18

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Adenine NucleotidesMajor topic
HeartMajor topic
MyocardiumMajor topic
Receptors, DrugMajor topic
Adenosine
Adenosine Diphosphate
Adenosine Monophosphate
Adenosine Triphosphate
Animals
Dipyridamole
Female
Guinea Pigs
In Vitro Techniques
Male
Myocardial Contraction
Rana pipiens
Receptors, Purinergic
Theophylline

Source PubMed

References29

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
17,357,212Potentiation by dilazep on the negative inotropic effect of adenosine on guinea-pig atria.Br J Pharmacol1980https://conductscience.org/library/papers/7357212PubMed
2994,531Purinergic receptors.J Theor Biol1976https://conductscience.org/library/papers/994531PubMed
3301,210An analysis of the action of ATP and related compounds on membrane current and tension components in bullfrog atrial muscle.Jpn J Physiol1977https://conductscience.org/library/papers/301210PubMed
45,932,600Field stimulation as a means of effecting the graded release of autonomic transmitters in isolated heart muscle.J Pharmacol Exp Ther1966https://conductscience.org/library/papers/5932600PubMed
54,687,130The action of ATP in the guinea-pig heart.Biochem Pharmacol1973https://conductscience.org/library/papers/4687130PubMed
65,438,268Cardiac effects of nucleosides after propranolol treatment of isolated hearts.Am J Physiol1970https://conductscience.org/library/papers/5438268PubMed
71,195,136Inhibitory effects of adenine nucleotide analogs on the isolated guinea-pig taenia coli.J Pharmacol Exp Ther1975https://conductscience.org/library/papers/1195136PubMed
814,266,674DIFFERENCES BETWEEN THE CHRONOTROPIC EFFECT OF ATP ON THE ISOLATED FROG HEART AND THE ISOLATED FROG VENTRICLE.Pflugers Arch Gesamte Physiol Menschen Tiere1965https://conductscience.org/library/papers/14266674PubMed
91,203,630Adenosine and dipyridamole actions and interactions on isolated coronary artery strips of cattle.Br J Pharmacol1975https://conductscience.org/library/papers/1203630PubMed
105,838,727Convenient apparatus for recording contractions of isolated heart muscle.J Appl Physiol1965https://conductscience.org/library/papers/5838727PubMed
11206,694Effects of exogenous ATP on contractile force and intracellular cyclic nucleotide levels in the hypodynamic frog ventricle [proceedings].J Physiol1978https://conductscience.org/library/papers/206694PubMed
124,689,986Left ventricular contractility and developed tension in the intact dog submitted to an intracoronary infusion of adenosine.J Physiol1973https://conductscience.org/library/papers/4689986PubMed
131,159,796Inhibition of slow action potentials of guinea pig atrial muscle by adenosine: a possible effect on Ca2+ influx.J Mol Cell Cardiol1975https://conductscience.org/library/papers/1159796PubMed
15206,915Dually innervated frog auricles for neuro-effector transmission studies.Pharmacol Res Commun1978https://conductscience.org/library/papers/206915PubMed
1614,044,462THE INFLUENCE OF URIDINE NUCLEOTIDES UPON THE ISOLATED FROG HEART.Pflugers Arch Gesamte Physiol Menschen Tiere1963https://conductscience.org/library/papers/14044462PubMed
171,149,797Evidence that prostaglandin is responsible for the 'rebound contraction' following stimulation of non-adrenergic, non-cholinergic ('purinergic') inhibitory nerves.Eur J Pharmacol1975https://conductscience.org/library/papers/1149797PubMed
18512,923The contribution of adenosine to the inhibitory actions of adenine nucleotides on the guinea-pig taenia coli: studies with phosphate-modified adenine nucleotide analogs and dipyridamole.J Pharmacol Exp Ther1979https://conductscience.org/library/papers/512923PubMed
196,246,248Adenosine depresses contractility and stimulates 3',5' cyclic nucleotide metabolism in the isolated frog ventricle.J Mol Cell Cardiol1980https://conductscience.org/library/papers/6246248PubMed
205,972,628Potentiation of adenosine and the adenine nucleotides by dipyridamole.Br J Pharmacol Chemother1966https://conductscience.org/library/papers/5972628PubMed
214,687,131The potentiation of the action of adenosine on the guinea-pig heart.Biochem Pharmacol1973https://conductscience.org/library/papers/4687131PubMed

See all 29 references

Cited by23

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 81 citations.

PMIDTitleJournalYearIn PapersSource
33,383,710P2 Receptors in Cardiac Myocyte Pathophysiology and Mechanotransduction.Int J Mol Sci2020https://conductscience.org/library/papers/33383710PubMed
25,527,177Cardiac purinergic signalling in health and disease.Purinergic Signal2015https://conductscience.org/library/papers/25527177PubMed
12,949,218ATP modulates intracellular Ca2+ and firing rate through a P2Y1 purinoceptor in cane toad pacemaker cells.J Physiol2003https://conductscience.org/library/papers/12949218PubMed
8,968,555Modulation by extracellular ATP of L-type calcium channels in guinea-pig single sinoatrial nodal cell.Br J Pharmacol1996https://conductscience.org/library/papers/8968555PubMed
8,851,504The effects of purine compounds on the isolated aorta of the frog Rana temporaria.Br J Pharmacol1996https://conductscience.org/library/papers/8851504PubMed
8,818,356The activation of P1- and P2-purinoceptors in the guinea-pig left atrium by diadenosine polyphosphates.Br J Pharmacol1996https://conductscience.org/library/papers/8818356PubMed
8,058,110Dual effect of ATP and UTP on rat atria: which types of receptors are involved?Naunyn Schmiedebergs Arch Pharmacol1994https://conductscience.org/library/papers/8058110PubMed
6,871,543The effect of adenyl compounds on the rat heart.Br J Pharmacol1983https://conductscience.org/library/papers/6871543PubMed
6,317,121Studies on the stereoselectivity of the P2-purinoceptor.Br J Pharmacol1983https://conductscience.org/library/papers/6317121PubMed
6,301,603Purine receptors in the guinea-pig internal anal sphincter.Br J Pharmacol1983https://conductscience.org/library/papers/6301603PubMed
6,201,751Capsaicin-induced stimulation of the guinea-pig atrium. Involvement of a novel sensory transmitter or a direct action on myocytes?Naunyn Schmiedebergs Arch Pharmacol1984https://conductscience.org/library/papers/6201751PubMed
6,090,638Ionic basis of the hyperpolarizing action of adenyl compounds on sinus venosus of the tortoise heart.J Physiol1984https://conductscience.org/library/papers/6090638PubMed
3,311,266Positive inotropic and chronotropic effects of trypsin and some other proteolytic enzymes in the guinea-pig heart.Br J Pharmacol1987https://conductscience.org/library/papers/3311266PubMed
3,006,665Extracellular ATP: effects, sources and fate.Biochem J1986https://conductscience.org/library/papers/3006665PubMed
2,992,653PACPX--a substituted xanthine--antagonizes both the A1 and A2 subclasses of the P1-purinoceptor: antagonism of the A2 subclass is competitive but antagonism of the A1 subclass is not.Br J Pharmacol1985https://conductscience.org/library/papers/2992653PubMed
2,984,586Demonstration of Ri-type adenosine receptors in bovine myocardium by radioligand binding.Naunyn Schmiedebergs Arch Pharmacol1985https://conductscience.org/library/papers/2984586PubMed
2,790,380Characterization of adenosine receptors in guinea-pig isolated left atria.Br J Pharmacol1989https://conductscience.org/library/papers/2790380PubMed
2,474,352The ability of denbufylline to inhibit cyclic nucleotide phosphodiesterase and its affinity for adenosine receptors and the adenosine re-uptake site.Br J Pharmacol1989https://conductscience.org/library/papers/2474352PubMed
2,455,577Adenosine inhibits the positive inotropic effect of 3-isobutyl-1-methylxanthine in papillary muscles without effect on cyclic AMP or cyclic GMP.Br J Pharmacol1988https://conductscience.org/library/papers/2455577PubMed
2,420,400Studies on the receptor mediating cyclic AMP-independent enhancement by adenosine of IgE-dependent mediator release from rat mast cells.Br J Pharmacol1986https://conductscience.org/library/papers/2420400PubMed

See all 23 cited by

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PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

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  • PMC's ID filePublic domain (US government)
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  • UniProtCC BY 4.0
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  • ClinicalTrials.govnone stated
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  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

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