Paper6978377

Human B cell differentiation. II. Pokeweed mitogen-responsive B cells belong to a surface immunoglobulin D-negative subpopulation.

Kuritani T and 1 other. J Exp Med, 1982. Cited by 163 papers, by iCite.

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ConductScience Library. Human B cell differentiation. II. Pokeweed mitogen-responsive B cells belong to a surface immunoglobulin D-negative subpopulation. Papers, record 6978377. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/6978377

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Human B cell differentiation. II. Pokeweed mitogen-responsive B cells belong to a surface immunoglobulin D-negative subpopulation.; PubMed
Journal: J Exp Med; PubMed
Year: 1982; PubMed
Publication types: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/6978377/; PubMed
DOI: https://doi.org/10.1084/jem.155.5.1561; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC2186664/; PubMed
The journal: https://conductscience.org/library/journal-index/2985109R; PubMed
Citations, by iCite: 163; iCite
Relative citation ratio, by iCite: 4.17; iCite
Revised in PubMed: 2019-05-08; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Kuritani T	T
2	Cooper MD	M D

Source PubMed

Topics12

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
B-Lymphocytes	Major topic
Immunoglobulin D	Major topic
Lymphocyte Activation	Major topic
Receptors, Antigen, B-Cell	Major topic
Animals
Cell Differentiation
Humans
Immunoglobulin M
Mice
Plasma Cells
Pokeweed Mitogens
Rosette Formation

Source PubMed

Show 6 more topicsShow fewer topics

Grants4

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by	Source
5M01-RR32	NCRR NIH HHS	United States		PubMed	PubMed
CA 13148	NCI NIH HHS	United States	P02CA013148	PubMed and NIH	NIH RePORTER
CA 16673	NCI NIH HHS	United States	P01CA016673	PubMed and NIH	NIH RePORTER
			P30CA013148	NIH	NIH RePORTER

References13

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	4,542,737	Immunoglobulin D as a lymphocyte receptor.	J Exp Med	1973	https://conductscience.org/library/papers/4542737	PubMed
2	1,096,382	Functional analysis of murine and human B lymphocyte subsets.	Transplant Rev	1975	https://conductscience.org/library/papers/1096382	PubMed
3	1,084,247	Ontogeny of B-lymphocyte differentiation induced by pokeweed mitogen.	Clin Immunol Immunopathol	1976	https://conductscience.org/library/papers/1084247	PubMed
4	794,413	The T cell dependence of B cell differentiation induced by pokeweed mitogen.	J Immunol	1976	https://conductscience.org/library/papers/794413	PubMed
5	301,090	Surface immunoglobulins of lipopolysaccharide-stimulated spleen cells. The behavior of IgM, IgD and IgG.	Eur J Immunol	1977	https://conductscience.org/library/papers/301090	PubMed
6	412,679	Immunofluorescent studies of the development of pre-B cells, B lymphocytes and immunoglobulin isotype diversity in humans.	Eur J Immunol	1977	https://conductscience.org/library/papers/412679	PubMed
7	306,413	Expression of IgD by murine lymphocytes. Loss of surface IgD indicates maturation of memory B cells.	J Exp Med	1978	https://conductscience.org/library/papers/306413	PubMed
8	96,179	Immunoglobulin secretion by human splenic lymphocytes in vitro: the effects of antibodies to IgM and IgD.	J Immunol	1978	https://conductscience.org/library/papers/96179	PubMed
9	6,966,197	Stimulation of human B lymphocytes by antibodies to IgM and IgG: functional evidence for the expression of IgG on B-lymphocyte surface membranes.	Clin Immunol Immunopathol	1980	https://conductscience.org/library/papers/6966197	PubMed
10	7,021,398	Roles of surface-bound immunoglobulin molecules in regulating the replication and maturation to immunoglobulin secretion of B lymphocytes.	Immunol Rev	1980	https://conductscience.org/library/papers/7021398	PubMed
11	6,268,340	Human B-lymphocyte subpopulations. I. Differentiation of density-separated B lymphocytes.	Clin Immunol Immunopathol	1981	https://conductscience.org/library/papers/6268340	PubMed
12	6,975,679	Rosette formation with mouse erythrocytes defines a population of human B lymphocytes unresponsive to pokeweed mitogen.	Clin Exp Immunol	1981	https://conductscience.org/library/papers/6975679	PubMed
13	6,801,181	Human b-cell differentiation. I. Analysis of immunoglobulin heavy chain switching using monoclonal anti-immunoglobulin M, G, and A antibodies and pokeweed mitogen-induced plasma cell differentiation.	J Exp Med	1982	https://conductscience.org/library/papers/6801181	PubMed

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Cited by44

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 163 citations.

PMID	Title	Journal	Year	In Papers	Source
18,474,725	Constitutive expression of IL-12R beta 2 on human multiple myeloma cells delineates a novel therapeutic target.	Blood	2008	https://conductscience.org/library/papers/18474725	PubMed
7,554,391	Delineation of producing ability of IgG and IgA subclasses by naive B cells in newborn infants and adult individuals.	Clin Exp Immunol	1995	https://conductscience.org/library/papers/7554391	PubMed
6,607,144	Evidence for B cell activation in patients with active rheumatoid arthritis.	Clin Exp Immunol	1984	https://conductscience.org/library/papers/6607144	PubMed
6,430,613	Human tonsil B lymphocyte function. I. The proliferative response to Staphylococcus aureus and pokeweed mitogen in relation to surface heavy chains mu and delta.	Clin Exp Immunol	1984	https://conductscience.org/library/papers/6430613	PubMed
6,375,389	Induction of maturation of human B-cell lymphomas in vitro. Morphologic changes in relation to immunoglobulin and DNA synthesis.	Am J Pathol	1984	https://conductscience.org/library/papers/6375389	PubMed
6,368,062	Mitogenic stimulation of malignant B cells. Chronic lymphocytic leukaemia: secretion of monoclonal IgM by in vitro-induced plasmablasts.	Clin Exp Immunol	1984	https://conductscience.org/library/papers/6368062	PubMed
6,345,586	Specific in vitro antimannan-rich antigen of Candida albicans antibody production by sensitized human blood lymphocytes.	J Clin Invest	1983	https://conductscience.org/library/papers/6345586	PubMed
6,309,895	Epstein-Barr virus-induced immunoglobulin synthesis by B cells from individuals with late-onset panhypogammaglobulinemia.	J Clin Immunol	1983	https://conductscience.org/library/papers/6309895	PubMed
6,304,226	Frequencies of the separate human B cell subsets activatable to Ig secretion by Epstein-Barr virus and pokeweed mitogen.	J Exp Med	1983	https://conductscience.org/library/papers/6304226	PubMed
6,302,818	B-lymphocyte subpopulation which forms rosettes with mouse erythrocytes increased in rheumatoid arthritis.	Rheumatol Int	1982	https://conductscience.org/library/papers/6302818	PubMed
6,235,242	T-cell regulation of IgG subclass expression by mitogen-induced plasma cells: soluble factors versus the T cells.	J Clin Immunol	1984	https://conductscience.org/library/papers/6235242	PubMed
6,195,284	A cloned major histocompatibility complex-restricted trinitrophenyl-reactive human helper T cell line that activates B cell subsets via two distinct pathways.	J Exp Med	1983	https://conductscience.org/library/papers/6195284	PubMed
4,006,304	Defective in vitro antibody production in response to pokeweed mitogen and influenza antigen in patients with Hodgkin's disease.	Clin Exp Immunol	1985	https://conductscience.org/library/papers/4006304	PubMed
3,878,748	Pokeweed mitogen and Staphylococcus aureus Cowan I induced immunoglobulin A synthesis by lymphocytes of IgA deficient blood donors.	Clin Exp Immunol	1985	https://conductscience.org/library/papers/3878748	PubMed
3,876,181	In vitro T-cell dependent B-cell activity in myasthenia gravis.	Clin Exp Immunol	1985	https://conductscience.org/library/papers/3876181	PubMed
3,874,259	Differential requirements of B cells from normal and allergic subjects for the induction of IgE synthesis by an alloreactive T cell clone.	J Exp Med	1985	https://conductscience.org/library/papers/3874259	PubMed
3,871,795	Effects of in vitro corticosteroids on B cell activation, proliferation, and differentiation.	J Clin Invest	1985	https://conductscience.org/library/papers/3871795	PubMed
3,490,940	Endothelial cell enhancement of PWM induced immunoglobulin synthesis by peripheral blood mononuclear cells.	Clin Exp Immunol	1986	https://conductscience.org/library/papers/3490940	PubMed
3,488,148	Human peripheral blood B cell subpopulations: surface IgD+ cells respond to pokeweed mitogen with plasma cell differentiation.	Clin Exp Immunol	1986	https://conductscience.org/library/papers/3488148	PubMed
3,486,820	Characteristics of human B cells responsive to the T-independent mitogen Branhamella catarrhalis.	Immunology	1986	https://conductscience.org/library/papers/3486820	PubMed

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Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ClinicalTrials.govNo license stated
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NIH RePORTER's grant and paper linksPublic domain
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PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
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NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
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