Paper · 6981

Mechanisms and regulation of biosynthesis of saturated fatty acids.

Volpe JJ and 1 other. Physiol Rev, 1976. Cited by 299 papers, by iCite.

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ConductScience Library. Mechanisms and regulation of biosynthesis of saturated fatty acids. Papers, record 6981. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/6981

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Mechanisms and regulation of biosynthesis of saturated fatty acids.; PubMed
Journal: Physiol Rev; PubMed
Year: 1976; PubMed
Publication types: Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S., Review; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/6981/; PubMed
DOI: https://doi.org/10.1152/physrev.1976.56.2.339; PubMed
The journal: https://conductscience.org/library/journal-index/0231714; PubMed
Citations, by iCite: 299; iCite
Relative citation ratio, by iCite: 8.81; iCite
Revised in PubMed: 2017-12-13; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Volpe JJ	J J
2	Vagelos PR	P R

Source PubMed

Topics24

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Acetyl-CoA Carboxylase	Major topic
Biotin	Major topic
Fatty Acid Synthases	Major topic
Fatty Acids	Major topic
Ligases	Major topic
Adipose Tissue
Animals
Apoenzymes
Bacteria
Carrier Proteins
Cattle
Chickens
Chloroplasts
Cyclic AMP
Eukaryota
Glucagon
Guinea Pigs
Humans
Liver
Molecular Conformation
Molecular Weight
Rabbits
Rats
Species Specificity

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

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Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

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References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by60

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 299 citations.

PMID	Title	Journal	Year	In Papers	Source
42,379,822	High-throughput screening system for antimycobacterial compounds using in vitro infected cells: construction and application to compounds in the Ōmura Natural Compound Library.	Microbiol Spectr	2026	https://conductscience.org/library/papers/42379822	PubMed
40,753,194	Genome-wide association study of blood vitamin D metabolites and bone remodelling markers in pigs.	BMC Genomics	2025	https://conductscience.org/library/papers/40753194	PubMed
37,358,513	Insulin Regulation of Hepatic Lipid Homeostasis.	Compr Physiol	2023	https://conductscience.org/library/papers/37358513	PubMed
34,328,722	Methylotroph Quorum Sensing Signal Identification by Inverse Stable Isotopic Labeling.	ACS Chem Biol	2021	https://conductscience.org/library/papers/34328722	PubMed
33,742,137	Reducing FASN expression sensitizes acute myeloid leukemia cells to differentiation therapy.	Cell Death Differ	2021	https://conductscience.org/library/papers/33742137	PubMed
31,900,237	Alteration of fatty acid oxidation by increased CPT1A on replicative senescence of placenta-derived mesenchymal stem cells.	Stem Cell Res Ther	2020	https://conductscience.org/library/papers/31900237	PubMed
31,080,524	The nutritional requirements of Caenorhabditis elegans.	Genes Nutr	2019	https://conductscience.org/library/papers/31080524	PubMed
30,201,012	DNA methylation footprints during soybean domestication and improvement.	Genome Biol	2018	https://conductscience.org/library/papers/30201012	PubMed
29,921,957	HEPATOKIN1 is a biochemistry-based model of liver metabolism for applications in medicine and pharmacology.	Nat Commun	2018	https://conductscience.org/library/papers/29921957	PubMed
24,836,606	Transgenic mice convert carbohydrates to essential fatty acids.	PLoS One	2014	https://conductscience.org/library/papers/24836606	PubMed

1 to 10 of 60

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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