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Paper698557

HBsAg-positive chronic liver disease: inhibition of DNA polymerase activity by vidarabine.

Chadwick RG and 4 others. Br Med J, 1978. Cited by 65 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. HBsAg-positive chronic liver disease: inhibition of DNA polymerase activity by vidarabine. Papers, record 698557. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/698557

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
HBsAg-positive chronic liver disease: inhibition of DNA polymerase activity by vidarabine.
PubMed
Journal
Br Med J
PubMed
Year
1978
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
65
iCite
Relative citation ratio, by iCite
2.79
iCite
Revised in PubMed
2019-05-01
PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Chadwick RGR G
2Bassendine MFM F
3Crawford EME M
4Thomas HCH C
5Sherlock SS

Source PubMed

Topics10

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Hepatitis BMajor topic
Nucleic Acid Synthesis InhibitorsMajor topic
VidarabineMajor topic
Adult
DNA-Directed DNA Polymerase
Hepatitis B Surface Antigens
Hepatitis B virus
Humans
Male
Middle Aged

Source PubMed

References5

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
1970,772"e" Antigen, Dane particles, and serum DNA polymerase activity in HBsAg carriers.Ann Intern Med1976https://conductscience.org/library/papers/970772PubMed
2967,200Type B hepatitis: the infectivity of blood positive for e antigen and DNA polymerase after accidental needlestick exposure.N Engl J Med1976https://conductscience.org/library/papers/967200PubMed
34,116,763New specificities in Australia antigen positive sera distinct from the Le Bouvier determinants.J Immunol1972https://conductscience.org/library/papers/4116763PubMed
453,657Incidence and clinical significance of e antigen and antibody in acute and chronic liver disease.Lancet1975https://conductscience.org/library/papers/53657PubMed
51,181,930DNA and DNA polymerase in the core of the Dane particle of hepatitis B.Am J Med Sci1975https://conductscience.org/library/papers/1181930PubMed

Cited by13

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 65 citations.

PMIDTitleJournalYearIn PapersSource
27,826,240The Pharmacological Potential of Non-ribosomal Peptides from Marine Sponge and Tunicates.Front Pharmacol2016https://conductscience.org/library/papers/27826240PubMed
7,251,131Influence of (+)-cyanidanol-3 on the leukocyte migration inhibition test carried out in the presence of purified protein derivative and hepatitis B surface antigen.Infect Immun1981https://conductscience.org/library/papers/7251131PubMed
6,780,982Quantum chemical calculation of the (S)-9-(2,3-dihydroxypropyl)adenine molecule.Nucleic Acids Res1980https://conductscience.org/library/papers/6780982PubMed
6,512,819Antiviral treatment of chronic hepatitis B virus infection.J R Soc Med1984https://conductscience.org/library/papers/6512819PubMed
6,490,167Clinicopathological response of HBsAg-positive chronic active hepatitis to adenine arabinoside: lack of correlation with DNA polymerase response.Infection1984https://conductscience.org/library/papers/6490167PubMed
6,231,885Comparison of properties of woodchuck hepatitis virus and human hepatitis B virus endogenous DNA polymerases.Antimicrob Agents Chemother1984https://conductscience.org/library/papers/6231885PubMed
6,210,232Selective penetration and pharmacological activity of lactosaminated albumin conjugates of adenine arabinoside 5-monophosphate (ara-AMP) in mouse liver.Gut1984https://conductscience.org/library/papers/6210232PubMed
6,179,819Successful treatment of HBs and HBeAg positive chronic liver disease: prolonged inhibition of viral replication by highly soluble adenine arabinoside 5'-monophosphate (ARA-AMP).Gut1982https://conductscience.org/library/papers/6179819PubMed
6,166,246Inhibition of hepatitis B virus deoxyribonucleic acid polymerase by the 5'-triphosphates of 9-beta-D-arabinofuranosyladenine and 1-beta-D-arabinofuranosylcytosine.Antimicrob Agents Chemother1981https://conductscience.org/library/papers/6166246PubMed
3,732,754Effects of adenine arabinoside on cellular immune responses in patients with chronic hepatitis B.Gastroenterol Jpn1986https://conductscience.org/library/papers/3732754PubMed
3,524,420Preliminary trial of recombinant fibroblast interferon in chronic hepatitis B virus infection.Antimicrob Agents Chemother1986https://conductscience.org/library/papers/3524420PubMed
2,410,328Randomised controlled trial of adenine arabinoside 5'-monophosphate (ARA-AMP) in chronic hepatitis B virus infection.Gut1985https://conductscience.org/library/papers/2410328PubMed
91,092The hepatitis B virus and its DNA polymerase: the prototype three-D virus.Mol Cell Biochem1979https://conductscience.org/library/papers/91092PubMed

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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