Paper · 6986027

Antacid versus cimetidine in preventing acute gastrointestinal bleeding. A randomized trial in 75 critically ill patients.

Priebe HJ and 4 others. N Engl J Med, 1980. Cited by 388 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Antacid versus cimetidine in preventing acute gastrointestinal bleeding. A randomized trial in 75 critically ill patients. Papers, record 6986027. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/6986027

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Antacid versus cimetidine in preventing acute gastrointestinal bleeding. A randomized trial in 75 critically ill patients.; PubMed
Journal: N Engl J Med; PubMed
Year: 1980; PubMed
Publication types: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/6986027/; PubMed
DOI: https://doi.org/10.1056/nejm198002213020802; PubMed
The journal: https://conductscience.org/library/journal-index/0255562; PubMed
Citations, by iCite: 388; iCite
Relative citation ratio, by iCite: 26.1; iCite
Revised in PubMed: 2019-12-10; PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Priebe HJ	H J
2	Skillman JJ	J J
3	Bushnell LS	L S
4	Long PC	P C
5	Silen W	W

Source PubMed

Topics20

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Antacids	Major topic
Cimetidine	Major topic
Critical Care	Major topic
Gastrointestinal Hemorrhage	Major topic
Guanidines	Major topic
Postoperative Complications	Major topic
Acute Disease
Aluminum Hydroxide
Clinical Trials as Topic
Drug Combinations
Female
Humans
Intubation, Gastrointestinal
Magnesium Hydroxide
Male
Middle Aged
Postoperative Care
Random Allocation
Risk
Simethicone

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by64

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 388 citations.

PMID	Title	Journal	Year	In Papers	Source
38,997,152	Pharmacological interventions for preventing upper gastrointestinal bleeding in people admitted to intensive care units: a network meta-analysis.	BMJ Evid Based Med	2025	https://conductscience.org/library/papers/38997152	PubMed
29,862,492	Interventions for preventing upper gastrointestinal bleeding in people admitted to intensive care units.	Cochrane Database Syst Rev	2018	https://conductscience.org/library/papers/29862492	PubMed
18,425,919	Antacids for preventing oesophagogastric variceal bleeding and rebleeding in cirrhotic patients.	Cochrane Database Syst Rev	2008	https://conductscience.org/library/papers/18425919	PubMed
10,400,401	Antacids revisited: a review of their clinical pharmacology and recommended therapeutic use.	Drugs	1999	https://conductscience.org/library/papers/10400401	PubMed
10,160,257	Pharmacoeconomic analysis of stress ulcer prophylaxis for critically ill patients.	Pharmacoeconomics	1996	https://conductscience.org/library/papers/10160257	PubMed
8,808,422	Control of gastric pH with ranitidine in patients with Crohn's disease receiving total parenteral nutrition. Comparison of two intravenous regimens.	J Gastroenterol	1996	https://conductscience.org/library/papers/8808422	PubMed
8,727,435	Assessment of gastric acidity in intensive care patients: intermittent pH registration cannot replace continuous pH monitoring.	Intensive Care Med	1996	https://conductscience.org/library/papers/8727435	PubMed
8,092,901	Optimal therapy for stress gastritis.	Ann Surg	1994	https://conductscience.org/library/papers/8092901	PubMed
7,748,030	General surgical complications can be predicted after cardiopulmonary bypass.	Ann Surg	1995	https://conductscience.org/library/papers/7748030	PubMed
7,401,190	Leukopenia with cimetidine.	J Natl Med Assoc	1980	https://conductscience.org/library/papers/7401190	PubMed

1 to 10 of 64

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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