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Paper · 70433

Platelet membrane defects in Glanzmann's thrombasthenia. Evidence for decreased amounts of two major glycoproteins.

Phillips DR and 1 other. J Clin Invest, 1977. Cited by 393 papers, by iCite.

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ConductScience Library. Platelet membrane defects in Glanzmann's thrombasthenia. Evidence for decreased amounts of two major glycoproteins. Papers, record 70433. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/70433

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Platelet membrane defects in Glanzmann's thrombasthenia. Evidence for decreased amounts of two major glycoproteins.
PubMed
Journal
J Clin Invest
PubMed
Year
1977
PubMed
Publication types
Clinical Trial, Comparative Study, Journal Article, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
393
iCite
Relative citation ratio, by iCite
9.48
iCite
Revised in PubMed
2018-11-13
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Phillips DRD R
2Agin PPP P

Source PubMed

Topics17

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Blood Platelet DisordersMajor topic
Blood PlateletsMajor topic
Blood ProteinsMajor topic
GlycoproteinsMajor topic
Purpura, ThrombocytopenicMajor topic
Blood Protein Electrophoresis
Cell Membrane
Chromatography, Affinity
Clinical Trials as Topic
Female
Hemorrhage
Humans
Iodine Radioisotopes
Isotope Labeling
Male
Staining and Labeling
Tritium

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References40

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
11,079,632Inherited defects of platelet function.Semin Hematol1975https://conductscience.org/library/papers/1079632PubMed
21,097,915Platelet physiology and abnormalities of platelet function (second of two parts).N Engl J Med1975https://conductscience.org/library/papers/1097915PubMed
31,169,691Specific roles for platelet surface glycoproteins in platelet function.Nature1975https://conductscience.org/library/papers/1169691PubMed
41,172,605Molecular differences of exposed surface proteins on thrombasthenic platelet plasma membranes.Nature1975https://conductscience.org/library/papers/1172605PubMed
51,201,247Effects of ADP and ATP on bovine fibrinogen- and ristocetin-induced platelet aggregation in Glanzmann's thrombasthenia.Br J Haematol1975https://conductscience.org/library/papers/1201247PubMed
61,239,828Clinical and genetic aspects of Glanzmann's thrombasthenia in Israel: report of 22 cases.Thromb Diath Haemorrh1975https://conductscience.org/library/papers/1239828PubMed
71,258,974The influence of aspirin and indomethacin on the platelet contractile wave.Am J Pathol1976https://conductscience.org/library/papers/1258974PubMed
81,276,130A Ca2+-activated protease possibly involved in myofibrillar protein turnover. Purification from porcine muscle.Biochemistry1976https://conductscience.org/library/papers/1276130PubMed
914,063,313LACTOPEROXIDASE. II. ISOLATION.J Biol Chem1963https://conductscience.org/library/papers/14063313PubMed
1014,166,539THE CORRECTION OF PROLONGED BLEEDING TIMES IN TWO BROTHERS BY PLATELET TRANSFUSIONS DESPITE NORMAL IN VITRO PLATELET TESTS.Pediatrics1964https://conductscience.org/library/papers/14166539PubMed

Cited by74

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 393 citations.

PMIDTitleJournalYearIn PapersSource
41,778,036Glanzmann thrombasthenia presenting with upper gastrointestinal bleeding: a case series and review of the literature.Front Med (Lausanne)2026https://conductscience.org/library/papers/41778036PubMed
40,988,584The integrin odyssey - a journey full of fundamental discoveries.J Cell Sci2025https://conductscience.org/library/papers/40988584PubMed
40,123,272Obstetric and Gynaecological Challenges and Outcomes in Women and Girls With Glanzmann's Thrombasthenia.Haemophilia2025https://conductscience.org/library/papers/40123272PubMed
40,033,798Management challenge of a rare concomitant platelet glycoprotein IV/CD36 and IIb/IIIa deficiencies: Case illustration.Transfusion2025https://conductscience.org/library/papers/40033798PubMed
39,677,151Bleeding Phenotype of Glanzmann Thrombasthenia (GT) and Treatment Outcomes in Over One Hundred Patients: A Two-Center Experience in North Pakistan.Cureus2024https://conductscience.org/library/papers/39677151PubMed
37,331,517Why platelet mechanotransduction matters for hemostasis and thrombosis.J Thromb Haemost2023https://conductscience.org/library/papers/37331517PubMed
36,704,147Novel homozygous silent mutation of ITGB3 gene caused Glanzmann thrombasthenia.Front Pediatr2022https://conductscience.org/library/papers/36704147PubMed
34,267,570Profiling the Genetic and Molecular Characteristics of Glanzmann Thrombasthenia: Can It Guide Current and Future Therapies?J Blood Med2021https://conductscience.org/library/papers/34267570PubMed
34,149,292Glanzmann Thrombasthenia: Perspectives from Clinical Practice on Accurate Diagnosis and Optimal Treatment Strategies.J Blood Med2021https://conductscience.org/library/papers/34149292PubMed
32,139,434Glanzmann thrombasthenia: genetic basis and clinical correlates.Haematologica2020https://conductscience.org/library/papers/32139434PubMed

1 to 10 of 74

See all 74 cited by

Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn Genes
LPO4,025PubTator's text mininghttps://conductscience.org/library/genes/4025

Source NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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