Paper · 70539

Extensive in vitro transcription of rous sarcoma virus RNA by avian myeloblastosis virus DNA polymerase and concurrent activation of the associated RNase H.

Darlix JL and 2 others. J Virol, 1977. Cited by 37 papers, by iCite.

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ConductScience Library. Extensive in vitro transcription of rous sarcoma virus RNA by avian myeloblastosis virus DNA polymerase and concurrent activation of the associated RNase H. Papers, record 70539. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/70539

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Extensive in vitro transcription of rous sarcoma virus RNA by avian myeloblastosis virus DNA polymerase and concurrent activation of the associated RNase H.; PubMed
Journal: J Virol; PubMed
Year: 1977; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/70539/; PubMed
DOI: https://doi.org/10.1128/jvi.23.3.659-668.1977; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC515877/; PubMed
The journal: https://conductscience.org/library/journal-index/0113724; PubMed
Citations, by iCite: 37; iCite
Relative citation ratio, by iCite: 0.78; iCite
Revised in PubMed: 2020-07-24; PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Darlix JL	J L
2	Bromley PA	P A
3	Spahr PF	P F

Source PubMed

Topics14

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Avian Leukosis Virus	Major topic
Avian Myeloblastosis Virus	Major topic
Avian Sarcoma Viruses	Major topic
DNA, Viral	Major topic
RNA, Viral	Major topic
RNA-Directed DNA Polymerase	Major topic
Ribonucleases	Major topic
Transcription, Genetic	Major topic
Base Sequence
Cell-Free System
Enzyme Activation
Escherichia coli
Nucleic Acid Hybridization
Oligonucleotides

Source PubMed

Grants0

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None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References22

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	1,174,504	Chain length determination of small double- and single-stranded DNA molecules by polyacrylamide gel electrophoresis.	Biochemistry	1975	https://conductscience.org/library/papers/1174504	PubMed
2	1,175,627	Quantitative film detection of 3H and 14C in polyacrylamide gels by fluorography.	Eur J Biochem	1975	https://conductscience.org/library/papers/1175627	PubMed
3	163,340	Molecular weight of RNA subunits of Rous sarcoma virus determined by electron microscopy.	J Virol	1975	https://conductscience.org/library/papers/163340	PubMed
4	169,390	Site on the RNA of an avian sarcoma virus at which primer is bound.	J Virol	1975	https://conductscience.org/library/papers/169390	PubMed
5	174,081	In vitro synthesis of full-length DNA transcripts of Rous sarcoma virus RNA by viral DNA polymerase.	Proc Natl Acad Sci U S A	1975	https://conductscience.org/library/papers/174081	PubMed
6	176,365	A physical map of the Rous sarcoma virus genome.	J Mol Biol	1976	https://conductscience.org/library/papers/176365	PubMed
7	180,433	Initiation sites of Rous sarcoma virus RNA-directed DNA synthesis in vitro.	Nature	1976	https://conductscience.org/library/papers/180433	PubMed
8	4,119,223	A single subunit from avian myeloblastosis virus with both RNA-directed DNA polymerase and ribonuclease H activity.	Proc Natl Acad Sci U S A	1973	https://conductscience.org/library/papers/4119223	PubMed
9	4,137,145	Purification and detection of reverse transcriptase in viruses and cells.	Methods Enzymol	1974	https://conductscience.org/library/papers/4137145	PubMed
10	4,317,039	Characterization of the products of DNA-directed DNA polymerases in oncogenic RNA viruses.	Nature	1970	https://conductscience.org/library/papers/4317039	PubMed

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Cited by18

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 37 citations.

PMID	Title	Journal	Year	In Papers	Source
6,804,945	Transcription of a Drosophila heat shock gene is heat-induced in Xenopus oocytes.	Proc Natl Acad Sci U S A	1982	https://conductscience.org/library/papers/6804945	PubMed
6,260,966	Viral DNA synthesized in vitro by avian retrovirus particles permeabilized with melittin. I. Kinetics of synthesis and size of minus- and plus-strand transcripts.	J Virol	1981	https://conductscience.org/library/papers/6260966	PubMed
6,202,882	RNA-primed initiation of Moloney murine leukemia virus plus strands by reverse transcriptase in vitro.	J Virol	1984	https://conductscience.org/library/papers/6202882	PubMed
6,199,510	Mechanism of RNA primer removal by the RNase H activity of avian myeloblastosis virus reverse transcriptase.	J Virol	1984	https://conductscience.org/library/papers/6199510	PubMed
6,186,442	Immunofluorescent characterization of DNA . RNA hybrids on polytene chromosomes of Trichosia pubescens (Diptera, sciaridae).	Chromosoma	1982	https://conductscience.org/library/papers/6186442	PubMed
3,039,172	The role of Moloney murine leukemia virus RNase H activity in the formation of plus-strand primers.	J Virol	1987	https://conductscience.org/library/papers/3039172	PubMed
2,578,196	RNase H-mediated release of the retrovirus RNA polyadenylate tail during reverse transcription.	J Virol	1985	https://conductscience.org/library/papers/2578196	PubMed
2,458,920	Small finger protein of avian and murine retroviruses has nucleic acid annealing activity and positions the replication primer tRNA onto genomic RNA.	EMBO J	1988	https://conductscience.org/library/papers/2458920	PubMed
2,426,698	Cloning and expression of cDNA for anti-müllerian hormone.	Proc Natl Acad Sci U S A	1986	https://conductscience.org/library/papers/2426698	PubMed
2,103,428	Transcriptional activation of 2 classes of genes during the hypersensitive reaction of tobacco leaves infiltrated with an incompatible isolate of the phytopathogenic bacterium Pseudomonas solanacearum.	Plant Mol Biol	1990	https://conductscience.org/library/papers/2103428	PubMed

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Drugs0

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Data0

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Data dates

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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