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Paper73346

The epsilon-(gamma-glutamyl)lysine crosslink and the catalytic role of transglutaminases.

Folk JE and 1 other. Adv Protein Chem, 1977. Cited by 547 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. The epsilon-(gamma-glutamyl)lysine crosslink and the catalytic role of transglutaminases. Papers, record 73346. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/73346

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
The epsilon-(gamma-glutamyl)lysine crosslink and the catalytic role of transglutaminases.
PubMed
Journal
Adv Protein Chem
PubMed
Year
1977
PubMed
Publication types
Journal Article, Review
PubMed
Citations, by iCite
547
iCite
Relative citation ratio, by iCite
15.1
iCite
Revised in PubMed
2019-12-10
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Folk JEJ E
2Finlayson JSJ S

Source PubMed

Topics16

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
DipeptidesMajor topic
gamma-GlutamyltransferaseMajor topic
Animals
Beta-Globulins
Chemical Phenomena
Chemistry
Factor XIII
Female
Fibrin
Fibrinogen
Humans
Lysine
Male
Pregnancy
Skin
Tissue Distribution

Source PubMed

Cited by152

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 547 citations.

PMIDTitleJournalYearIn PapersSource
42,539,240Transglutaminase 2 Deletion Enhances Astrocyte-to-Neuron Metabolic Support and Attenuates Subacute Pathology Following Repetitive Mild Traumatic Brain Injury.bioRxiv2026https://conductscience.org/library/papers/42539240PubMed
41,387,034Reimagining biogenic amine signaling in the brain and beyond.Trends Neurosci2026https://conductscience.org/library/papers/41387034PubMed
39,272,486
Transglutaminase Crosslinked Milk Protein Concentrate and Micellar Casein Concentrate: Impact on the Functionality of Imitation Mozzarella Cheese Manufactured on a Small Scale Using a Rapid Visco Analyzer.
Foods2024https://conductscience.org/library/papers/39272486PubMed
38,933,264Complement-Coagulation Cross-talk: Factor H-mediated regulation of the Complement Classical Pathway activation by fibrin clots.Front Immunol2024https://conductscience.org/library/papers/38933264PubMed
38,397,040Pathogenetic Contributions and Therapeutic Implications of Transglutaminase 2 in Neurodegenerative Diseases.Int J Mol Sci2024https://conductscience.org/library/papers/38397040PubMed
35,922,533Sulfated glycosaminoglycans inhibit transglutaminase 2 by stabilizing its closed conformation.Sci Rep2022https://conductscience.org/library/papers/35922533PubMed
35,785,306Naturally Occurring Epsilon Gamma Glutamyl Lysine Isopeptide Crosslinks in Human Neuroblastoma SH-SY5Y Cells.ACS Omega2022https://conductscience.org/library/papers/35785306PubMed
35,563,567Tissue Transglutaminase Knock-Out Preadipocytes and Beige Cells of Epididymal Fat Origin Possess Decreased Mitochondrial Functions Required for Thermogenesis.Int J Mol Sci2022https://conductscience.org/library/papers/35563567PubMed
35,563,115Exploring Diverse Coagulation Factor XIII Subunit Expression Datasets: A Bioinformatic Analysis.Int J Mol Sci2022https://conductscience.org/library/papers/35563115PubMed
35,017,479Transglutaminase 3 crosslinks the secreted gel-forming mucus component Mucin-2 and stabilizes the colonic mucus layer.Nat Commun2022https://conductscience.org/library/papers/35017479PubMed
34,786,551Cooperation of cell adhesion and autophagy in the brain: Functional roles in development and neurodegenerative disease.Matrix Biol Plus2021https://conductscience.org/library/papers/34786551PubMed
34,242,352Evaluation of mass spectrometry MS/MS spectra for the presence of isopeptide crosslinked peptides.PLoS One2021https://conductscience.org/library/papers/34242352PubMed
34,150,394Relationship Between Villous Atrophy and tTGA Levels in Dyspeptic Patients: A Case Series.Cureus2021https://conductscience.org/library/papers/34150394PubMed
33,802,692Factor XIII-A: An Indispensable "Factor" in Haemostasis and Wound Healing.Int J Mol Sci2021https://conductscience.org/library/papers/33802692PubMed
33,659,327In vitro Crosslinking Reactions and Substrate Incorporation Assays for The Identification of Transglutaminase-2 Protein Substrates.Bio Protoc2020https://conductscience.org/library/papers/33659327PubMed
33,642,842Discovery of sultam-containing small-molecule disruptors of the huntingtin-calmodulin protein-protein interaction.Med Chem Res2020https://conductscience.org/library/papers/33642842PubMed
33,127,469Epigenetic regulators of neuronal ferroptosis identify novel therapeutics for neurological diseases: HDACs, transglutaminases, and HIF prolyl hydroxylases.Neurobiol Dis2021https://conductscience.org/library/papers/33127469PubMed
33,057,112Differentiating Staphylococcus infection-associated glomerulonephritis and primary IgA nephropathy: a mass spectrometry-based exploratory study.Sci Rep2020https://conductscience.org/library/papers/33057112PubMed
32,521,655Signature Ions in MS/MS Spectra for Dansyl-Aminohexyl-QQIV Adducts on Lysine.Molecules2020https://conductscience.org/library/papers/32521655PubMed
32,485,850Transglutaminase 2 Has Metabolic and Vascular Regulatory Functions Revealed by In Vivo Activation of Alpha1-Adrenergic Receptor.Int J Mol Sci2020https://conductscience.org/library/papers/32485850PubMed

See all 152 cited by

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • References
  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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