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Paper75940

Cellular and genetic restrictions in the immunoregulatory activity of alpha-fetoprotein. I. Selective inhibition of anti-Ia-associated proliferative reactions.

Peck AB and 2 others. J Exp Med, 1978. Cited by 48 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Cellular and genetic restrictions in the immunoregulatory activity of alpha-fetoprotein. I. Selective inhibition of anti-Ia-associated proliferative reactions. Papers, record 75940. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/75940

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Cellular and genetic restrictions in the immunoregulatory activity of alpha-fetoprotein. I. Selective inhibition of anti-Ia-associated proliferative reactions.
PubMed
Journal
J Exp Med
PubMed
Year
1978
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
48
iCite
Relative citation ratio, by iCite
1.62
iCite
Revised in PubMed
2021-12-03
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Peck ABA B
2Murgita RAR A
3Wigzell HH

Source PubMed

Topics12

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
H-2 AntigensMajor topic
IsoantigensMajor topic
Lymphocyte ActivationMajor topic
T-LymphocytesMajor topic
alpha-FetoproteinsMajor topic
Animals
Epitopes
Genes, MHC Class II
Immunologic Memory
Immunosuppression Therapy
Lymphocyte Culture Test, Mixed
Mice

Source PubMed

References45

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
11,078,839Expression of T-cell differentiation antigens on effector cells in cell-mediated cytotoxicity in vitro. Evidence for functional heterogeneity related to the surface phenotype of T cells.J Exp Med1975https://conductscience.org/library/papers/1078839PubMed
21,092,798Functional subclasses of T-lymphocytes bearing different Ly antigens. I. The generation of functionally distinct T-cell subclasses is a differentiative process independent of antigen.J Exp Med1975https://conductscience.org/library/papers/1092798PubMed
31,176,892Serum albumin is essential for in vitro growth of activated human lymphocytes.J Exp Med1975https://conductscience.org/library/papers/1176892PubMed
411,993,317I-region-associated determinants: expression on mitogen-stimulated lymphocytes and detection by cytotoxic T cells.Eur J Immunol1975https://conductscience.org/library/papers/11993317PubMed
5123,259Suppression of maternal responsiveness to paternal antigen by maternal plasma.J Immunol1975https://conductscience.org/library/papers/123259PubMed
6127,410Clonal isolation of alloantigen-reactive T-cells and characterization of their memory functions.Transplant Rev1975https://conductscience.org/library/papers/127410PubMed
7133,763The effects of crude and purified human gonadotropin on in vitro stimulated human lymphocyte cultures.Cell Immunol1976https://conductscience.org/library/papers/133763PubMed
8142,745Environmental and genetic control of T cell activation in vitro: a study using isolated alloantigen-activated T cell clones.Immunol Rev1977https://conductscience.org/library/papers/142745PubMed
9142,788Mitogen-stimulated lymphoid cells from human newborns suppress the proliferation of maternal lymphocytes actoss a cell-impermeable membrane.J Immunol1977https://conductscience.org/library/papers/142788PubMed
10234,178Ly antigens as markers for functionally distinct subpopulations of thymus-derived lymphocytes of the mouse.Nature1975https://conductscience.org/library/papers/234178PubMed
114,120,489Reduction of lymphocyte transformation by a factor produced by gastrointestinal cancer.Lancet1973https://conductscience.org/library/papers/4120489PubMed
124,188,334Impaired lymphocyte transformation in ataxia-telangiectasia in part due to a plasma inhibitory factor.J Immunol1969https://conductscience.org/library/papers/4188334PubMed
134,205,974The embryo as a transplant.Sci Am1974https://conductscience.org/library/papers/4205974PubMed
144,267,208Cell-mediated lympholysis. Importance of serologically defined H-2 regions.J Exp Med1973https://conductscience.org/library/papers/4267208PubMed
154,270,409Immune responses in vitro. VII. Differentiation of H-2 and non-H-2 alloantigens of the mouse by a dual mixed leukocyte culture.Transplantation1973https://conductscience.org/library/papers/4270409PubMed
164,271,346Immune responses in vitro. II. Mixed leukocyte interaction in a protein-free medium.Eur J Immunol1973https://conductscience.org/library/papers/4271346PubMed
174,271,347Immune responses in vitro. 3. Enhancement of the mouse mixed lymphocyte interaction by isologous and homologous sera.Eur J Immunol1973https://conductscience.org/library/papers/4271347PubMed
184,547,153Cell-mediated cytotoxicity to trinitrophenyl-modified syngeneic lymphocytes.Eur J Immunol1974https://conductscience.org/library/papers/4547153PubMed
194,551,691Immune responses in vitro. I. Culture conditions for antibody synthesis.Cell Immunol1972https://conductscience.org/library/papers/4551691PubMed
204,589,987Maturation of the humoral immune response in mice.J Exp Med1974https://conductscience.org/library/papers/4589987PubMed

See all 45 references

Cited by9

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 48 citations.

PMIDTitleJournalYearIn PapersSource
24,999,358Proteomic analysis of domestic pig pancreas during development using two-dimensional electrophoresis and matrix-assisted laser desorption/ionization-time of flight mass spectrometry.Lab Anim Res2014https://conductscience.org/library/papers/24999358PubMed
6,190,602Response of human peripheral blood lymphocytes in the presence of cord sera: relationship of lymphocyte transformation with number of pregnancies and levels of alpha-fetoprotein.Clin Exp Immunol1983https://conductscience.org/library/papers/6190602PubMed
6,172,344Inhibitory action of pig alpha-fetoprotein through early activated thymocyte surface Na+, K+-adenosinetriphosphatase.Folia Microbiol (Praha)1981https://conductscience.org/library/papers/6172344PubMed
2,475,575Isolation and characterization of a distinct immunoregulatory isoform of alpha-fetoprotein produced by the normal fetus.J Exp Med1989https://conductscience.org/library/papers/2475575PubMed
1,383,274Isolation and partial characterization of a specific alpha-fetoprotein receptor on human monocytes.J Clin Invest1992https://conductscience.org/library/papers/1383274PubMed
453,325Immunologic and genetic factors influencing reproduction. A review.Am J Pathol1979https://conductscience.org/library/papers/453325PubMed
160,849Segregation of human peripheral blood lymphocytes according to their affinity for insolubilized histamine. Principal differences between males and females.Clin Exp Immunol1979https://conductscience.org/library/papers/160849PubMed
81,256Cellular and genetic restrictions in the immunoregulatory activity of alpha-fetoprotein. II. Alpha-fetoprotein-induced suppression of cytotoxic T lymphocyte development.J Exp Med1978https://conductscience.org/library/papers/81256PubMed
78,493Adult murine T cells activated in vitro by alpha-fetoprotein and naturally occurring T cells in newborn mice: identity in function and cell surface differentiation antigens.Proc Natl Acad Sci U S A1978https://conductscience.org/library/papers/78493PubMed

Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
AFP174PubTator's text mininghttps://conductscience.org/library/genes/174NCBI Gene
HCCS3,052PubTator's text mininghttps://conductscience.org/library/genes/3052NCBI Gene

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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