Paper75940
Cellular and genetic restrictions in the immunoregulatory activity of alpha-fetoprotein. I. Selective inhibition of anti-Ia-associated proliferative reactions.
Peck AB and 2 others. J Exp Med, 1978. Cited by 48 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
Cite this record
ConductScience Library. Cellular and genetic restrictions in the immunoregulatory activity of alpha-fetoprotein. I. Selective inhibition of anti-Ia-associated proliferative reactions. Papers, record 75940. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/75940
Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Cellular and genetic restrictions in the immunoregulatory activity of alpha-fetoprotein. I. Selective inhibition of anti-Ia-associated proliferative reactions.
- PubMed
Topics12
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| H-2 Antigens | Major topic |
| Isoantigens | Major topic |
| Lymphocyte Activation | Major topic |
| T-Lymphocytes | Major topic |
| alpha-Fetoproteins | Major topic |
| Animals | |
| Epitopes | |
| Genes, MHC Class II | |
| Immunologic Memory | |
| Immunosuppression Therapy | |
| Lymphocyte Culture Test, Mixed | |
| Mice |
Source PubMed
References45
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 1,078,839 | Expression of T-cell differentiation antigens on effector cells in cell-mediated cytotoxicity in vitro. Evidence for functional heterogeneity related to the surface phenotype of T cells. | J Exp Med | 1975 | https://conductscience.org/library/papers/1078839 | PubMed |
| 2 | 1,092,798 | Functional subclasses of T-lymphocytes bearing different Ly antigens. I. The generation of functionally distinct T-cell subclasses is a differentiative process independent of antigen. | J Exp Med | 1975 | https://conductscience.org/library/papers/1092798 | PubMed |
| 3 | 1,176,892 | Serum albumin is essential for in vitro growth of activated human lymphocytes. | J Exp Med | 1975 | https://conductscience.org/library/papers/1176892 | PubMed |
| 4 | 11,993,317 | I-region-associated determinants: expression on mitogen-stimulated lymphocytes and detection by cytotoxic T cells. | Eur J Immunol | 1975 | https://conductscience.org/library/papers/11993317 | PubMed |
| 5 | 123,259 | Suppression of maternal responsiveness to paternal antigen by maternal plasma. | J Immunol | 1975 | https://conductscience.org/library/papers/123259 | PubMed |
| 6 | 127,410 | Clonal isolation of alloantigen-reactive T-cells and characterization of their memory functions. | Transplant Rev | 1975 | https://conductscience.org/library/papers/127410 | PubMed |
| 7 | 133,763 | The effects of crude and purified human gonadotropin on in vitro stimulated human lymphocyte cultures. | Cell Immunol | 1976 | https://conductscience.org/library/papers/133763 | PubMed |
| 8 | 142,745 | Environmental and genetic control of T cell activation in vitro: a study using isolated alloantigen-activated T cell clones. | Immunol Rev | 1977 | https://conductscience.org/library/papers/142745 | PubMed |
| 9 | 142,788 | Mitogen-stimulated lymphoid cells from human newborns suppress the proliferation of maternal lymphocytes actoss a cell-impermeable membrane. | J Immunol | 1977 | https://conductscience.org/library/papers/142788 | PubMed |
| 10 | 234,178 | Ly antigens as markers for functionally distinct subpopulations of thymus-derived lymphocytes of the mouse. | Nature | 1975 | https://conductscience.org/library/papers/234178 | PubMed |
| 11 | 4,120,489 | Reduction of lymphocyte transformation by a factor produced by gastrointestinal cancer. | Lancet | 1973 | https://conductscience.org/library/papers/4120489 | PubMed |
| 12 | 4,188,334 | Impaired lymphocyte transformation in ataxia-telangiectasia in part due to a plasma inhibitory factor. | J Immunol | 1969 | https://conductscience.org/library/papers/4188334 | PubMed |
| 13 | 4,205,974 | The embryo as a transplant. | Sci Am | 1974 | https://conductscience.org/library/papers/4205974 | PubMed |
| 14 | 4,267,208 | Cell-mediated lympholysis. Importance of serologically defined H-2 regions. | J Exp Med | 1973 | https://conductscience.org/library/papers/4267208 | PubMed |
| 15 | 4,270,409 | Immune responses in vitro. VII. Differentiation of H-2 and non-H-2 alloantigens of the mouse by a dual mixed leukocyte culture. | Transplantation | 1973 | https://conductscience.org/library/papers/4270409 | PubMed |
| 16 | 4,271,346 | Immune responses in vitro. II. Mixed leukocyte interaction in a protein-free medium. | Eur J Immunol | 1973 | https://conductscience.org/library/papers/4271346 | PubMed |
| 17 | 4,271,347 | Immune responses in vitro. 3. Enhancement of the mouse mixed lymphocyte interaction by isologous and homologous sera. | Eur J Immunol | 1973 | https://conductscience.org/library/papers/4271347 | PubMed |
| 18 | 4,547,153 | Cell-mediated cytotoxicity to trinitrophenyl-modified syngeneic lymphocytes. | Eur J Immunol | 1974 | https://conductscience.org/library/papers/4547153 | PubMed |
| 19 | 4,551,691 | Immune responses in vitro. I. Culture conditions for antibody synthesis. | Cell Immunol | 1972 | https://conductscience.org/library/papers/4551691 | PubMed |
| 20 | 4,589,987 | Maturation of the humoral immune response in mice. | J Exp Med | 1974 | https://conductscience.org/library/papers/4589987 | PubMed |
Cited by9
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 48 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 24,999,358 | Proteomic analysis of domestic pig pancreas during development using two-dimensional electrophoresis and matrix-assisted laser desorption/ionization-time of flight mass spectrometry. | Lab Anim Res | 2014 | https://conductscience.org/library/papers/24999358 | PubMed |
| 6,190,602 | Response of human peripheral blood lymphocytes in the presence of cord sera: relationship of lymphocyte transformation with number of pregnancies and levels of alpha-fetoprotein. | Clin Exp Immunol | 1983 | https://conductscience.org/library/papers/6190602 | PubMed |
| 6,172,344 | Inhibitory action of pig alpha-fetoprotein through early activated thymocyte surface Na+, K+-adenosinetriphosphatase. | Folia Microbiol (Praha) | 1981 | https://conductscience.org/library/papers/6172344 | PubMed |
| 2,475,575 | Isolation and characterization of a distinct immunoregulatory isoform of alpha-fetoprotein produced by the normal fetus. | J Exp Med | 1989 | https://conductscience.org/library/papers/2475575 | PubMed |
| 1,383,274 | Isolation and partial characterization of a specific alpha-fetoprotein receptor on human monocytes. | J Clin Invest | 1992 | https://conductscience.org/library/papers/1383274 | PubMed |
| 453,325 | Immunologic and genetic factors influencing reproduction. A review. | Am J Pathol | 1979 | https://conductscience.org/library/papers/453325 | PubMed |
| 160,849 | Segregation of human peripheral blood lymphocytes according to their affinity for insolubilized histamine. Principal differences between males and females. | Clin Exp Immunol | 1979 | https://conductscience.org/library/papers/160849 | PubMed |
| 81,256 | Cellular and genetic restrictions in the immunoregulatory activity of alpha-fetoprotein. II. Alpha-fetoprotein-induced suppression of cytotoxic T lymphocyte development. | J Exp Med | 1978 | https://conductscience.org/library/papers/81256 | PubMed |
| 78,493 | Adult murine T cells activated in vitro by alpha-fetoprotein and naturally occurring T cells in newborn mice: identity in function and cell surface differentiation antigens. | Proc Natl Acad Sci U S A | 1978 | https://conductscience.org/library/papers/78493 | PubMed |
Genes2
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes | Source |
|---|---|---|---|---|
| AFP | 174 | PubTator's text mining | https://conductscience.org/library/genes/174 | NCBI Gene |
| HCCS | 3,052 | PubTator's text mining | https://conductscience.org/library/genes/3052 | NCBI Gene |
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
None in this release
- Grants
- Trials
- Comments and corrections
- Drugs
- Data
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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