Paper · 765327

Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 1. General introduction.

Khorana HG and 19 others. J Biol Chem, 1976. Cited by 56 papers, by iCite.

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ConductScience Library. Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 1. General introduction. Papers, record 765327. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/765327

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 1. General introduction.; PubMed
Journal: J Biol Chem; PubMed
Year: 1976; PubMed
Publication types: Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S.; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/765327/; PubMed
The journal: https://conductscience.org/library/journal-index/2985121R; PubMed
Citations, by iCite: 56; iCite
Relative citation ratio, by iCite: 1.31; iCite
Revised in PubMed: 2021-02-10; PubMed

Authors20

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Khorana HG	H G
2	Agarwal KL	K L
3	Besmer P	P
4	Büchi H	H
5	Caruthers MH	M H
6	Cashion PJ	P J
7	Fridkin M	M
8	Jay E	E
9	Kleppe K	K
10	Kleppe R	R

1 to 10 of 20Source PubMed

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Topics12

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
DNA, Bacterial	Major topic
Escherichia coli	Major topic
Genes	Major topic
RNA, Transfer	Major topic
Base Sequence
Nucleic Acid Conformation
Oligodeoxyribonucleotides
Polydeoxyribonucleotides
Polynucleotide Ligases
Protein Biosynthesis
Transcription, Genetic
Tyrosine

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by16

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 56 citations.

PMID	Title	Journal	Year	In Papers	Source
39,955,471	Polymerase Chain Reaction: A Toolbox for Molecular Discovery.	Mol Biotechnol	2026	https://conductscience.org/library/papers/39955471	PubMed
23,322,070	Frontiers and approaches to chemical synthesis of oligodeoxyribonucleotides.	Molecules	2013	https://conductscience.org/library/papers/23322070	PubMed
22,572,789	The Saccharomyces cerevisiae SCRaMbLE system and genome minimization.	Bioeng Bugs	2012	https://conductscience.org/library/papers/22572789	PubMed
20,010,598	Genome engineering.	Nat Biotechnol	2009	https://conductscience.org/library/papers/20010598	PubMed
7,008,029	Synthesis of the human insulin gene. Part III. Chemical synthesis of 5'-phosphomonoester group containing deoxyribooligonucleotides by the modified phosphotriester method. Its application in the synthesis of seventeen fragments constituting human insulin C-chain DNA.	Nucleic Acids Res	1980	https://conductscience.org/library/papers/7008029	PubMed
6,894,029	A study of the efficiency and the problem of sulfonation of several condensing reagents and their mechanisms for the chemical synthesis of deoxyoligoribonucleotides.	Nucleic Acids Res	1980	https://conductscience.org/library/papers/6894029	PubMed
909,785	Chemical synthesis of the hexanucleotide d(A-C-C-A-G-C) required to isolate fibroin mRNA on an affinity column.	Nucleic Acids Res	1977	https://conductscience.org/library/papers/909785	PubMed
866,189	Rapid synthesis of oligodeoxyribonucleotides: a new solid-phase method.	Nucleic Acids Res	1977	https://conductscience.org/library/papers/866189	PubMed
866,187	Studies of gene control regions. III. Binding of synthetic and modified synthetic lac operator DNAs to lactose repressor.	Nucleic Acids Res	1977	https://conductscience.org/library/papers/866187	PubMed
787,807	[Total synthesis of a gene].	Naturwissenschaften	1976	https://conductscience.org/library/papers/787807	PubMed

1 to 10 of 16

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data1

The data bank entries PubMed's record names. Trial numbers are under Trials.

Data bank	Accession
GENBANK	K02250

Source GENBANK

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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