Paper · 7806572

Expression of a myosin regulatory light chain phosphorylation site mutant complements the cytokinesis and developmental defects of Dictyostelium RMLC null cells.

Ostrow BD and 2 others. J Cell Biol, 1994. Cited by 83 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Cite this record

ConductScience Library. Expression of a myosin regulatory light chain phosphorylation site mutant complements the cytokinesis and developmental defects of Dictyostelium RMLC null cells. Papers, record 7806572. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/7806572

On this page

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Expression of a myosin regulatory light chain phosphorylation site mutant complements the cytokinesis and developmental defects of Dictyostelium RMLC null cells.; PubMed
Journal: J Cell Biol; PubMed
Year: 1994; PubMed
Publication types: Journal Article, Research Support, U.S. Gov't, P.H.S.; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/7806572/; PubMed
DOI: https://doi.org/10.1083/jcb.127.6.1945; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC2120314/; PubMed
The journal: https://conductscience.org/library/journal-index/0375356; PubMed
Citations, by iCite: 83; iCite
Relative citation ratio, by iCite: 1.82; iCite
Revised in PubMed: 2019-05-08; PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Ostrow BD	B D
2	Chen P	P
3	Chisholm RL	R L

Source PubMed

Topics20

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Cell Division	Major topic
Dictyostelium	Major topic
Mutation	Major topic
Myosins	Major topic
Actins
Adenosine Triphosphatases
Amino Acid Sequence
Animals
Base Sequence
Cell Compartmentation
Enzyme Activation
Fluorescent Antibody Technique
Genetic Complementation Test
Molecular Sequence Data
Mutagenesis, Site-Directed
Myosin-Light-Chain Kinase
Phosphorylation
Recombinant Proteins
Serine
Structure-Activity Relationship

Source PubMed

Grants1

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by
GM39264	NIGMS NIH HHS	United States	R01GM039264	PubMed and NIH

Source NIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections1

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

Kind	PMID	Title	In Papers
Comment in	7,806,558	Regulation of Dictyostelium myosin II by phosphorylation: what is essential and what is important?	https://conductscience.org/library/papers/7806558

Source PubMed

References71

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	3,029,544	Purification and characterization of Chlamydomonas flagellar dyneins.	Methods Enzymol	1986	https://conductscience.org/library/papers/3029544	PubMed
2	3,318,880	Myosin structure and function in cell motility.	Annu Rev Cell Biol	1987	https://conductscience.org/library/papers/3318880	PubMed
3	6,260,022	Regulation of smooth muscle actomyosin.	Annu Rev Physiol	1981	https://conductscience.org/library/papers/6260022	PubMed
4	1,899,668	Spatial and temporal control of nonmuscle myosin localization: identification of a domain that is necessary for myosin filament disassembly in vivo.	J Cell Biol	1991	https://conductscience.org/library/papers/1899668	PubMed
5	3,036,866	Phosphorylation of the 20,000-dalton light chain of smooth muscle myosin by the calcium-activated, phospholipid-dependent protein kinase. Phosphorylation sites and effects of phosphorylation.	J Biol Chem	1987	https://conductscience.org/library/papers/3036866	PubMed
6	1,651,931	Characterization and bacterial expression of the Dictyostelium myosin light chain kinase cDNA. Identification of an autoinhibitory domain.	J Biol Chem	1991	https://conductscience.org/library/papers/1651931	PubMed
7	1,533,639	Actin-activated Mg-ATPase activity of Dictyostelium myosin II. Effects of filament formation and heavy chain phosphorylation.	J Biol Chem	1992	https://conductscience.org/library/papers/1533639	PubMed
8	8,440,724	Chimeric regulatory light chains as probes of smooth muscle myosin function.	J Biol Chem	1993	https://conductscience.org/library/papers/8440724	PubMed
9	6,276,562	Evidence for sub-families of actin genes in Dictyostelium as determined by comparisons of 3' end sequences.	J Mol Biol	1981	https://conductscience.org/library/papers/6276562	PubMed
10	6,118,372	Reversible phosphorylation of smooth muscle myosin, heavy meromyosin, and platelet myosin.	J Biol Chem	1981	https://conductscience.org/library/papers/6118372	PubMed

1 to 10 of 71

See all 71 references

Cited by38

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 83 citations.

PMID	Title	Journal	Year	In Papers	Source
36,825,780	Myosin II regulatory light chain phosphorylation and formin availability modulate cytokinesis upon changes in carbohydrate metabolism.	Elife	2023	https://conductscience.org/library/papers/36825780	PubMed
36,273,263	Particle-based model of mechanosensory contractility kit assembly.	Biophys J	2022	https://conductscience.org/library/papers/36273263	PubMed
33,606,000	Filament evanescence of myosin II and smooth muscle function.	J Gen Physiol	2021	https://conductscience.org/library/papers/33606000	PubMed
32,038,836	Cytotoxic Effects on HL-60 Cells of Myosin Light Chain Kinase Inhibitor ML-7 Alone and in Combination with Flavonoids.	Toxicol Res	2009	https://conductscience.org/library/papers/32038836	PubMed
26,827,725	Various Themes of Myosin Regulation.	J Mol Biol	2016	https://conductscience.org/library/papers/26827725	PubMed
24,846,395	Moving towards a paradigm: common mechanisms of chemotactic signaling in Dictyostelium and mammalian leukocytes.	Cell Mol Life Sci	2014	https://conductscience.org/library/papers/24846395	PubMed
22,761,196	Cytokinesis mechanics and mechanosensing.	Cytoskeleton (Hoboken)	2012	https://conductscience.org/library/papers/22761196	PubMed
22,565,821	Nonmuscle myosin-2: mix and match.	Cell Mol Life Sci	2013	https://conductscience.org/library/papers/22565821	PubMed
20,709,619	Cytokinesis through biochemical-mechanical feedback loops.	Semin Cell Dev Biol	2010	https://conductscience.org/library/papers/20709619	PubMed
19,570,908	Regulation of fission yeast myosin-II function and contractile ring dynamics by regulatory light-chain and heavy-chain phosphorylation.	Mol Biol Cell	2009	https://conductscience.org/library/papers/19570908	PubMed

1 to 10 of 38

See all 38 cited by

Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes
MYLK	4,638	PubTator's text mining	https://conductscience.org/library/genes/4638

Source NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this paper from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/papers/v1/7806572

GET https://conductscience.org/api/papers/v1/7806572/references?page=2

API reference For AI assistants