Paper · 7829879

Tissue inhibitor of metalloproteinases-1 is decreased and activated gelatinases are increased in chronic wounds.

Bullen EC and 6 others. J Invest Dermatol, 1995. Cited by 207 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Tissue inhibitor of metalloproteinases-1 is decreased and activated gelatinases are increased in chronic wounds. Papers, record 7829879. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/7829879

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Tissue inhibitor of metalloproteinases-1 is decreased and activated gelatinases are increased in chronic wounds.; PubMed
Journal: J Invest Dermatol; PubMed
Year: 1995; PubMed
Publication types: Journal Article, Research Support, Non-U.S. Gov't; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/7829879/; PubMed
DOI: https://doi.org/10.1111/1523-1747.ep12612786; PubMed
The journal: https://conductscience.org/library/journal-index/0426720; PubMed
Citations, by iCite: 207; iCite
Relative citation ratio, by iCite: 7.23; iCite
Revised in PubMed: 2022-04-08; PubMed

Authors7

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Bullen EC	E C
2	Longaker MT	M T
3	Updike DL	D L
4	Benton R	R
5	Ladin D	D
6	Hou Z	Z
7	Howard EW	E W

Source PubMed

Topics10

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Gelatinases	Major topic
Glycoproteins	Major topic
Wounds and Injuries	Major topic
Chronic Disease
Enzyme Activation
Exudates and Transudates
Humans
Matrix Metalloproteinase Inhibitors
Tissue Inhibitor of Metalloproteinases
Wound Healing

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by57

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 207 citations.

PMID	Title	Journal	Year	In Papers	Source
41,544,231	Platelet α-granule cargo packaging and endocytosis are important for normal mouse skin wound healing.	Blood Adv	2026	https://conductscience.org/library/papers/41544231	PubMed
41,038,874	Integrated machine learning analysis of proteomic and transcriptomic data identifies healing associated targets in diabetic wound repair.	Sci Rep	2025	https://conductscience.org/library/papers/41038874	PubMed
40,819,659	A Review of Chronic Wounds and Their Impact on Negative Affect, Cognition, and Quality of Life.	Int Wound J	2025	https://conductscience.org/library/papers/40819659	PubMed
38,924,411	Alcaligenes faecalis corrects aberrant matrix metalloproteinase expression to promote reepithelialization of diabetic wounds.	Sci Adv	2024	https://conductscience.org/library/papers/38924411	PubMed
38,505,642	Advances in the Sensing and Treatment of Wound Biofilms.	Angew Chem Weinheim Bergstr Ger	2022	https://conductscience.org/library/papers/38505642	PubMed
36,838,568	The Use of Proteins, Lipids, and Carbohydrates in the Management of Wounds.	Molecules	2023	https://conductscience.org/library/papers/36838568	PubMed
36,142,583	A Preliminary Direct Comparison of the Inflammatory Reduction and Growth Factor Production Capabilities of Three Commercially Available Wound Products: Collagen Sheet, Manuka Honey Sheet, and a Novel Bioengineered Collagen Derivative + Manuka Honey + Hydroxyapatite Sheet.	Int J Mol Sci	2022	https://conductscience.org/library/papers/36142583	PubMed
36,110,054	The biological and physiological impact of the performance of wound dressings.	Int Wound J	2023	https://conductscience.org/library/papers/36110054	PubMed
35,381,119	Wound fluid sampling methods for proteomic studies: A scoping review.	Wound Repair Regen	2022	https://conductscience.org/library/papers/35381119	PubMed
35,327,667	Defining the Protease and Protease Inhibitor (P/PI) Proteomes of Healthy and Diseased Human Skin by Modified Systematic Review.	Biomolecules	2022	https://conductscience.org/library/papers/35327667	PubMed

1 to 10 of 57

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Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes
TIMP1	7,076	PubTator's text mining	https://conductscience.org/library/genes/7076

Source NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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