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Paper · 786607

Metoclopramide: a review of its pharmacological properties and clinical use.

Pinder RM and 4 others. Drugs, 1976. Cited by 360 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Metoclopramide: a review of its pharmacological properties and clinical use. Papers, record 786607. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/786607

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Metoclopramide: a review of its pharmacological properties and clinical use.
PubMed
Journal
Drugs
PubMed
Year
1976
PubMed
Publication types
Clinical Trial, Journal Article, Review
PubMed
Citations, by iCite
360
iCite
Relative citation ratio, by iCite
19.7
iCite
Revised in PubMed
2026-10-11
PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Pinder RMR M
2Brogden RNR N
3Sawyer PRP R
4Speight TMT M
5Avery GSG S

Source PubMed

Topics19

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
MetoclopramideMajor topic
Animals
Basal Ganglia Diseases
Cardiovascular System
Central Nervous System
Clinical Trials as Topic
Digestive System
Emetics
Female
Gastrointestinal Diseases
Humans
Intestinal Absorption
Kinetics
Male
Muscle, Smooth
Peristalsis
Pregnancy
Prolactin
Vomiting

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References171

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
14,614,247A double-blind study of metoclopramide in symptomatic peptic oesophagitis.Postgrad Med J1973https://conductscience.org/library/papers/4614247PubMed
2765,184Effect of oral metoclopramide on gastroesophageal reflux in the post-cibal state.Gastroenterology1976https://conductscience.org/library/papers/765184PubMed
35,457,288Transformation and excretion of drugs in biological systems. 3. Separatory determination of metoclopramide and its N4-glucuronide and N4-sulfonate in rabbit urine and bile.Chem Pharm Bull (Tokyo)1970https://conductscience.org/library/papers/5457288PubMed
41,171,487Pharmacological evidence for cerebral dopamine receptor blockade by metoclopramide in rodents.Psychopharmacologia1975https://conductscience.org/library/papers/1171487PubMed
54,960,492Gastrointestinal actions of metoclopramide. An experimental study.Gastroenterology1967https://conductscience.org/library/papers/4960492PubMed
61,183,218Metoclopramide in hiccup.Curr Med Res Opin1975https://conductscience.org/library/papers/1183218PubMed
74,554,726Clinical trial of metoclopramide on postvagotomy gastric stasis.Arch Surg1972https://conductscience.org/library/papers/4554726PubMed
85,440,179Dystonic reactions in children caused by metoclopramide.Arch Dis Child1970https://conductscience.org/library/papers/5440179PubMed
96,647The absorption and elimination of metoclopramide in three animal species.J Pharm Pharmacol1976https://conductscience.org/library/papers/6647PubMed
104,759,239Acute drug-induced extrapyramidal syndromes.Practitioner1973https://conductscience.org/library/papers/4759239PubMed

1 to 10 of 171

See all 171 references

Cited by66

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 360 citations.

PMIDTitleJournalYearIn PapersSource
41,471,388Evaluation of Antiproliferative Activity and Molecular Modeling Studies of Some Novel Benzimidazolone-Bridged Hybrid Compounds.Pharmaceuticals (Basel)2025https://conductscience.org/library/papers/41471388PubMed
38,023,576Efficacy of metoclopramide for prevention of gastric regurgitation during endotracheal intubation in the emergency department: A randomized controlled trial.Int J Crit Illn Inj Sci2023https://conductscience.org/library/papers/38023576PubMed
34,882,284Prevention of Chemotherapy-Induced Nausea and Vomiting in the Older Patient: Optimizing Outcomes.Drugs Aging2022https://conductscience.org/library/papers/34882284PubMed
33,273,807Quality by Design (QbD)-Based Numerical and Graphical Optimization Technique for the Development of Osmotic Pump Controlled-Release Metoclopramide HCl Tablets.Drug Des Devel Ther2020https://conductscience.org/library/papers/33273807PubMed
30,233,361A History of Drug Discovery for Treatment of Nausea and Vomiting and the Implications for Future Research.Front Pharmacol2018https://conductscience.org/library/papers/30233361PubMed
29,745,438High exposure compared with standard exposure to metoclopramide associated with a higher risk of parkinsonism: a nationwide population-based cohort study.Br J Clin Pharmacol2018https://conductscience.org/library/papers/29745438PubMed
29,492,850RETRACTED ARTICLE: Combination Antiemetic Regimens for Prevention of Postoperative Nausea and Vomiting : Focus on High-Risk Patients.Clin Drug Investig2002https://conductscience.org/library/papers/29492850PubMed
28,421,555Pharmacological Agents Affecting Emesis : A Review (Part II).Drugs1992https://conductscience.org/library/papers/28421555PubMed
27,227,028The involvement of TRPV1 in emesis and anti-emesis.Temperature (Austin)2015https://conductscience.org/library/papers/27227028PubMed
25,877,021Metoclopramide role in preventing ileus after cesarean, a clinical trial.Eur J Clin Pharmacol2015https://conductscience.org/library/papers/25877021PubMed

1 to 10 of 66

See all 66 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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