Paper · 799247

The effects of the relA gene on the synthesis of aminoacyl-tRNA synthetases and other transcription and translation proteins in Escherichia coli A.

Blumenthal RM and 3 others. Mol Gen Genet, 1976. Cited by 76 papers, by iCite.

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ConductScience Library. The effects of the relA gene on the synthesis of aminoacyl-tRNA synthetases and other transcription and translation proteins in Escherichia coli A. Papers, record 799247. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/799247

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: The effects of the relA gene on the synthesis of aminoacyl-tRNA synthetases and other transcription and translation proteins in Escherichia coli A.; PubMed
Journal: Mol Gen Genet; PubMed
Year: 1976; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/799247/; PubMed
DOI: https://doi.org/10.1007/bf00268530; PubMed
The journal: https://conductscience.org/library/journal-index/0125036; PubMed
Citations, by iCite: 76; iCite
Relative citation ratio, by iCite: 1.78; iCite
Revised in PubMed: 2019-07-25; PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Blumenthal RM	R M
2	Lemaux PG	P G
3	Neidhardt FC	F C
4	Dennis PP	P P

Source PubMed

Topics10

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Amino Acyl-tRNA Synthetases	Major topic
Escherichia coli	Major topic
Genes	Major topic
Protein Biosynthesis	Major topic
Transcription, Genetic	Major topic
Mutation
Peptide Elongation Factors
Ribosomal Proteins
Species Specificity
Temperature

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References36

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	4,337,104	Regulation of ribosomal and transfer ribonucleic acid synthesis in Escherichia coli B-r.	J Biol Chem	1972	https://conductscience.org/library/papers/4337104	PubMed
2	775,495	A mutant of Escherichia coli with an altered elongation factor Tu.	Proc Natl Acad Sci U S A	1976	https://conductscience.org/library/papers/775495	PubMed
3	320,192	Transient rates of synthesis of five amionacyl-transfer ribonucleic acid synthetases during a shift-up of Escherichia coli.	J Bacteriol	1977	https://conductscience.org/library/papers/320192	PubMed
4	781,673	Regulation of transcription factor rho and the alpha subunit of RNA polymerase in Escherichia coli B/r.	Proc Natl Acad Sci U S A	1976	https://conductscience.org/library/papers/781673	PubMed
5	4,579,428	Reconstitution of Escherichia coli 30 S ribosomal subunits from purified molecular components.	J Biol Chem	1973	https://conductscience.org/library/papers/4579428	PubMed
6	4,897,207	The ribosomal proteins of Escherichia coli. II. Chemical and physical characterization of the 30S ribosomal proteins.	Biochemistry	1969	https://conductscience.org/library/papers/4897207	PubMed
7	1,108,010	Identification of a gene for the alpha-subunit of RNA polymerase at the str-spc region of the Escherichia coli chromosome.	Proc Natl Acad Sci U S A	1975	https://conductscience.org/library/papers/1108010	PubMed
8	765,336	Syntheses of elongation factors Tu and G are under stringent control in Escherichia coli.	J Biol Chem	1976	https://conductscience.org/library/papers/765336	PubMed
9	1,108,000	Content of elongation factor Tu in Escherichia coli.	Proc Natl Acad Sci U S A	1975	https://conductscience.org/library/papers/1108000	PubMed
10	318,645	Chemical measurement of steady-state levels of ten aminoacyl-transfer ribonucleic acid synthetases in Escherichia coli.	J Bacteriol	1977	https://conductscience.org/library/papers/318645	PubMed

1 to 10 of 36

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Cited by36

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 76 citations.

PMID	Title	Journal	Year	In Papers	Source
38,438,391	A coarse-grained bacterial cell model for resource-aware analysis and design of synthetic gene circuits.	Nat Commun	2024	https://conductscience.org/library/papers/38438391	PubMed
32,782,250	Mechanisms of drug interactions between translation-inhibiting antibiotics.	Nat Commun	2020	https://conductscience.org/library/papers/32782250	PubMed
27,223,819	Aminoacyl-tRNA Synthetases in the Bacterial World.	EcoSal Plus	2016	https://conductscience.org/library/papers/27223819	PubMed
22,653,948	Global transcriptional analysis of the stringent response in Enterococcus faecalis.	Microbiology (Reading)	2012	https://conductscience.org/library/papers/22653948	PubMed
16,961,923	Global gene expression during stringent response in Corynebacterium glutamicum in presence and absence of the rel gene encoding (p)ppGpp synthase.	BMC Genomics	2006	https://conductscience.org/library/papers/16961923	PubMed
15,678,157	Selective charging of tRNA isoacceptors induced by amino-acid starvation.	EMBO Rep	2005	https://conductscience.org/library/papers/15678157	PubMed
11,948,165	Bacillus subtilis functional genomics: global characterization of the stringent response by proteome and transcriptome analysis.	J Bacteriol	2002	https://conductscience.org/library/papers/11948165	PubMed
10,809,680	mRNA composition and control of bacterial gene expression.	J Bacteriol	2000	https://conductscience.org/library/papers/10809680	PubMed
7,312,036	Dual function transcripts specifying tRNA and mRNA.	Nature	1981	https://conductscience.org/library/papers/7312036	PubMed
6,988,414	Protein identifications of O'Farrell two-dimensional gels: locations of 81 Escherichia coli proteins.	J Bacteriol	1980	https://conductscience.org/library/papers/6988414	PubMed

1 to 10 of 36

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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