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Paper · 8201088

Low intramucosal pH is associated with failure to acidify the gastric lumen in response to pentagastrin.

Higgins D and 2 others. Intensive Care Med, 1994. Cited by 29 papers, by iCite.

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ConductScience Library. Low intramucosal pH is associated with failure to acidify the gastric lumen in response to pentagastrin. Papers, record 8201088. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/8201088

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Low intramucosal pH is associated with failure to acidify the gastric lumen in response to pentagastrin.
PubMed
Journal
Intensive Care Med
PubMed
Year
1994
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
29
iCite
Relative citation ratio, by iCite
1.75
iCite
Revised in PubMed
2026-10-10
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Higgins DD
2Mythen MGM G
3Webb ARA R

Source PubMed

Topics21

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
AchlorhydriaMajor topic
Gastric AcidMajor topic
Gastric Acidity DeterminationMajor topic
Gastric MucosaMajor topic
IschemiaMajor topic
PentagastrinMajor topic
Aged
Blood Gas Analysis
Critical Illness
Cross Infection
Female
Humans
Hydrogen-Ion Concentration
Intensive Care Units
Male
Middle Aged
Pneumonia
Prospective Studies
Risk Factors
Severity of Illness Index
Survival Rate

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections1

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

KindPMIDTitleIn Papers
Comment in8,201,103Intramucosal pH.https://conductscience.org/library/papers/8201103

Source PubMed

References20

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
13,085,638Prediction of the development of sigmoid ischemia on the day of aortic operations. Indirect measurements of intramural pH in the colon.Arch Surg1986https://conductscience.org/library/papers/3085638PubMed
21,979,444Endothelium-derived relaxing factor participates in the increased blood flow in response to pentagastrin in the rat stomach mucosa.Proc Biol Sci1990https://conductscience.org/library/papers/1979444PubMed
31,346,170Gastric intramucosal pH as a therapeutic index of tissue oxygenation in critically ill patients.Lancet1992https://conductscience.org/library/papers/1346170PubMed
46,409,705Predictive value of intramural pH and other risk factors for massive bleeding from stress ulceration.Gastroenterology1983https://conductscience.org/library/papers/6409705PubMed
53,122,979Gastric exocrine "failure" in critically ill patients: incidence and associated features.Br Med J (Clin Res Ed)1988https://conductscience.org/library/papers/3122979PubMed
61,617,980Gastric mucosal pH as a prognostic index of mortality in critically ill patients.Crit Care Med1992https://conductscience.org/library/papers/1617980PubMed
72,598,416Intramucosal pH measurement with tonometers for detecting gastrointestinal ischemia in porcine hemorrhagic shock.Circ Shock1989https://conductscience.org/library/papers/2598416PubMed
83,100,137Predictive value of the stomach wall pH for complications after cardiac operations: comparison with other monitoring.Crit Care Med1987https://conductscience.org/library/papers/3100137PubMed
92,221,061Validation of tonometric measurement of gut intramural pH during endotoxemia and mesenteric occlusion in pigs.Am J Physiol1990https://conductscience.org/library/papers/2221061PubMed
102,055,052Nosocomial pneumonia in the critically ill: product of aspiration or translocation?Crit Care Med1991https://conductscience.org/library/papers/2055052PubMed

1 to 10 of 20

See all 20 references

Cited by8

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 29 citations.

PMIDTitleJournalYearIn PapersSource
27,408,044Gastric Tonometry as a Prognostic Index of Mortality in Sepsis.Med J Armed Forces India2007https://conductscience.org/library/papers/27408044PubMed
25,886,762Does gastric tonometry-guided therapy reduce total mortality in critically ill patients?Crit Care2015https://conductscience.org/library/papers/25886762PubMed
18,991,471Effect of proton pump inhibitors on gastric juice volume, gastric pH and gastric intramucosal pH in critically ill patients : a randomized, double-blind, placebo-controlled study.Clin Drug Investig2008https://conductscience.org/library/papers/18991471PubMed
11,819,529Reduced gastric acid production in burn shock period and its significance in the prevention and treatment of acute gastric mucosal lesions.World J Gastroenterol2000https://conductscience.org/library/papers/11819529PubMed
11,094,465Gastric intramucosal pH measurement.Crit Care1997https://conductscience.org/library/papers/11094465PubMed
9,681,775Monitoring the hepato-splanchnic region in the critically ill patient. Measurement techniques and clinical relevance.Intensive Care Med1998https://conductscience.org/library/papers/9681775PubMed
8,708,169Effect of nasogastric suction and ranitidine on the calculated gastric intramucosal pH.Intensive Care Med1996https://conductscience.org/library/papers/8708169PubMed
8,201,103Intramucosal pH.Intensive Care Med1994https://conductscience.org/library/papers/8201103PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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