ConductScience.org, home
Papers
API referenceFor AI assistants

Paper85683

The induction of cell-mediated immunity and tolerance with protein antigens coupled to syngeneic lymphoid cells.

Miller SD and 2 others. J Exp Med, 1979. Cited by 222 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Download JSON
Cite this record

ConductScience Library. The induction of cell-mediated immunity and tolerance with protein antigens coupled to syngeneic lymphoid cells. Papers, record 85683. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/85683

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
The induction of cell-mediated immunity and tolerance with protein antigens coupled to syngeneic lymphoid cells.
PubMed
Journal
J Exp Med
PubMed
Year
1979
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
222
iCite
Relative citation ratio, by iCite
3.85
iCite
Revised in PubMed
2021-12-03
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Miller SDS D
2Wetzig RPR P
3Claman HNH N

Source PubMed

Topics15

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Immune ToleranceMajor topic
Immunity, CellularMajor topic
LymphocytesMajor topic
Membrane ProteinsMajor topic
ProteinsMajor topic
Animals
Cytochrome c Group
Dose-Response Relationship, Immunologic
Female
Immunosuppression Therapy
Mice
Mice, Inbred BALB C
Solubility
Spleen
gamma-Globulins

Source PubMed

References37

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
11,084,399Ly and Ia antigen phenotypes of T cells involved in delayed-type hypersensitivity and in suppression.J Exp Med1976https://conductscience.org/library/papers/1084399PubMed
21,084,899Requirements for induction of T cell tolerance to DNFB: efficiency of membrane-associated DNFB.J Immunol1976https://conductscience.org/library/papers/1084899PubMed
31,086,779Suppressor cell induction in vitro. II. Cellular requirements of suppressor cell induction.Eur J Immunol1976https://conductscience.org/library/papers/1086779PubMed
41,086,885Role of self-carriers in the immune response and tolerance. I. B-cell unresponsiveness and cytotoxic T-cell immunity induced by haptenated syngeneic lymphoid cells.J Exp Med1976https://conductscience.org/library/papers/1086885PubMed
51,087,316The induction of hapten-specific T cell tolerance by using hapten-modified lymphoid cells. I. Characteristics of tolerance induction.J Immunol1976https://conductscience.org/library/papers/1087316PubMed
61,101,472The role of specific suppressor T cells in immune tolerance.Transplant Rev1975https://conductscience.org/library/papers/1101472PubMed
71,254,950Tolerance and contact sensitivity to DNFB in mice. V. Induction of tolerance with DNP compounds and with free and membrane-associated DNFB.J Immunol1976https://conductscience.org/library/papers/1254950PubMed
81,273,519A comparison of four methods for measuring cutaneous delayed- type hypersensitivity reactions to protein antigens in the mouse.Scand J Immunol1976https://conductscience.org/library/papers/1273519PubMed
914,283,201PHAGOCYTOSIS OF THE ANTIGEN, A CRUCIAL STEP IN THE INDUCTION OF THE PRIMARY RESPONSE.Proc Natl Acad Sci U S A1965https://conductscience.org/library/papers/14283201PubMed
10300,756The role of the macrophage as the stimulator cell in contact sensitivity.J Immunol1977https://conductscience.org/library/papers/300756PubMed
11301,091The induction of hapten-specific T cell tolerance using hapten-modified lymphoid membranes. II. Relative roles of suppressor T cells and clone inhibition in the tolerant state.Eur J Immunol1977https://conductscience.org/library/papers/301091PubMed
12303,257A splenic requirement for the generation of suppressor T cells.J Immunol1977https://conductscience.org/library/papers/303257PubMed
13304,865Tolerance and contact sensitivity to DNFA in mice. VIII. Identification of distinct T cell subpopulations that mediate in vivo and in vitro manifestations of delayed hypersensitivity.J Immunol1978https://conductscience.org/library/papers/304865PubMed
14305,458
Genetic restrictions for the induction of suppressor T cells by hapten-modified lymphoid cells in tolerance to 1-fluoro-2,4-dinitrobenzene contact sensitivity. Role of the H-2D region of the major histocompatibility complex.
J Exp Med1978https://conductscience.org/library/papers/305458PubMed
15329,141Ia antigen expression on human epidermal Langerhans cells.Nature1977https://conductscience.org/library/papers/329141PubMed
164,103,727Cellular events during induction of immunologic unresponsiveness in adult mice.J Immunol1971https://conductscience.org/library/papers/4103727PubMed
174,130,110
Failure to induce tolerance to 2,4-dinitrochlorobenzene contact sensitivity with a 2,4-dinitrophenyl (DNP) conjugate of a copolymer of D-glutamic acid and D-lysine, a specific tolerogen for DNP B cells.
J Immunol1974https://conductscience.org/library/papers/4130110PubMed
184,179,469Studies on the induction of immunologic unresponsiveness. 3. Antigen form and mouse strain variation.J Immunol1969https://conductscience.org/library/papers/4179469PubMed
194,397,662
Carrier function in anti-hapten antibody responses. IV. Experimental conditions for the induction of hapten-specific tolerance or for the stimulation of anti-hapten anamnestic responses by "nonimmunogenic" hapten-polypeptide conjugates.
J Exp Med1971https://conductscience.org/library/papers/4397662PubMed
204,399,614Brain-associated theta antigen: reactivity of rabbit anti-mouse brain with mouse lymphoid cells.Cell Immunol1971https://conductscience.org/library/papers/4399614PubMed

See all 37 references

Cited by76

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 222 citations.

PMIDTitleJournalYearIn PapersSource
42,842,659Kupffer cells are key mediators of antigen-specific immune tolerance by peptide-coupled red blood cells.Sci Adv2026https://conductscience.org/library/papers/42842659PubMed
41,499,508Allospecific splenic Tr1 cells drive effector T cell exhaustion through up-regulated Areg-EGFR signaling to promote transplant tolerance.Sci Adv2026https://conductscience.org/library/papers/41499508PubMed
41,481,727STING/type I interferon pathway is required for antigen-containing PLGA nanoparticle- and apoptotic cell-induced CD4+ T cell tolerance.Sci Adv2026https://conductscience.org/library/papers/41481727PubMed
40,103,389Current status of xenotransplantation from an immunobiological standpoint.Clin Transplant Res2025https://conductscience.org/library/papers/40103389PubMed
38,694,761Biomaterial-enhanced treg cell immunotherapy: A promising approach for transplant medicine and autoimmune disease treatment.Bioact Mater2024https://conductscience.org/library/papers/38694761PubMed
38,086,932Therapeutic induction of antigen-specific immune tolerance.Nat Rev Immunol2024https://conductscience.org/library/papers/38086932PubMed
36,221,192Nanoparticle dose and antigen loading attenuate antigen-specific T-cell responses.Biotechnol Bioeng2023https://conductscience.org/library/papers/36221192PubMed
34,987,468Can Immune Tolerance Be Re-established in Neuromyelitis Optica?Front Neurol2021https://conductscience.org/library/papers/34987468PubMed
33,854,514Emerging Therapeutics for Immune Tolerance: Tolerogenic Vaccines, T cell Therapy, and IL-2 Therapy.Front Immunol2021https://conductscience.org/library/papers/33854514PubMed
32,296,421The Emerging Jamboree of Transformative Therapies for Autoimmune Diseases.Front Immunol2020https://conductscience.org/library/papers/32296421PubMed
31,508,270Immunomodulatory Nanosystems.Adv Sci (Weinh)2019https://conductscience.org/library/papers/31508270PubMed
31,337,690Apoptotic Cell-Induced, Antigen-Specific Immunoregulation to Treat Experimental Antimyeloperoxidase GN.J Am Soc Nephrol2019https://conductscience.org/library/papers/31337690PubMed
30,944,161Nanoparticles Bearing TSH Receptor Protein and a Tolerogenic Molecule Do Not Induce Immune Tolerance but Exacerbate Thyroid Autoimmunity in hTSHR/NOD.H2h4 Mice.J Immunol2019https://conductscience.org/library/papers/30944161PubMed
30,804,535Antigen-specific therapeutic approaches for autoimmunity.Nat Biotechnol2019https://conductscience.org/library/papers/30804535PubMed
30,418,444Polymeric micro- and nanoparticles for immune modulation.Biomater Sci2018https://conductscience.org/library/papers/30418444PubMed
30,352,312Overcoming challenges in treating autoimmuntity: Development of tolerogenic immune-modifying nanoparticles.Nanomedicine2019https://conductscience.org/library/papers/30352312PubMed
28,414,079In vivo reprogramming of immune cells: Technologies for induction of antigen-specific tolerance.Adv Drug Deliv Rev2017https://conductscience.org/library/papers/28414079PubMed
27,648,463Restoring immune tolerance in neuromyelitis optica: Part I.Neurol Neuroimmunol Neuroinflamm2016https://conductscience.org/library/papers/27648463PubMed
27,131,971Autoantigen-specific immunosuppression with tolerogenic peripheral blood cells prevents relapses in a mouse model of relapsing-remitting multiple sclerosis.J Transl Med2016https://conductscience.org/library/papers/27131971PubMed
26,568,117Manipulating regulatory T cells: a promising strategy to treat autoimmunity.Immunotherapy2015https://conductscience.org/library/papers/26568117PubMed

See all 76 cited by

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this paper from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/papers/v1/85683

GET https://conductscience.org/api/papers/v1/85683/references?page=2

API referenceFor AI assistants