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Paper874101

Studies on the role of cephalic-vagal stimulation in the acid secretory response to eating in normal human subjects.

Richardson CT and 4 others. J Clin Invest, 1977. Cited by 138 papers, by iCite.

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ConductScience Library. Studies on the role of cephalic-vagal stimulation in the acid secretory response to eating in normal human subjects. Papers, record 874101. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/874101

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Studies on the role of cephalic-vagal stimulation in the acid secretory response to eating in normal human subjects.
PubMed
Journal
J Clin Invest
PubMed
Year
1977
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
138
iCite
Relative citation ratio, by iCite
5.01
iCite
Revised in PubMed
2018-11-30
PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Richardson CTC T
2Walsh JHJ H
3Cooper KAK A
4Feldman MM
5Fordtran JSJ S

Source PubMed

Topics15

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
BrainMajor topic
EatingMajor topic
Gastric JuiceMajor topic
GastrinsMajor topic
Vagus NerveMajor topic
Adult
Female
Food
Glucose
Humans
Kinetics
Male
Middle Aged
Sodium Chloride
Stomach

Source PubMed

References12

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
114,323,728THE DETERMINATION OF GASTRIC ACIDITY BY THE GLASS ELECTRODE.Gastroenterology1965https://conductscience.org/library/papers/14323728PubMed
213,902,300Stimulation of secretion of acid by distention of denervated fundic pouches in dogs.Gastroenterology1961https://conductscience.org/library/papers/13902300PubMed
313,902,299Secretion of acid and pepsin in response to distention of vagally innervated fundic gland area in dogs.Gastroenterology1962https://conductscience.org/library/papers/13902299PubMed
51,129,697The effect of vagal stimulation on gastrin release and acid secretion.Surgery1975https://conductscience.org/library/papers/1129697PubMed
64,215,124Influence of feeding and sham feeding upon serum gastrin and gastric acid secretion in control subjects and duodenal ulcer patients.Scand J Gastroenterol1974https://conductscience.org/library/papers/4215124PubMed
7239,883Chemicals bathing the oxyntic gland area stimulate acid secretion in dog.Gastroenterology1975https://conductscience.org/library/papers/239883PubMed
84,685,087Gastric acid secretion rate and buffer content of the stomach after eating. Results in normal subjects and in patients with duodenal ulcer.J Clin Invest1973https://conductscience.org/library/papers/4685087PubMed
95,055,748Plasma gastrin and gastric acid responses to sham feeding and feeding in dogs.Gastroenterology1972https://conductscience.org/library/papers/5055748PubMed
104,917,141Comparison of the gastric secretory responses following the administration of histamine acid phosphate and pentagastrin by separate continuous intravenous infusions or by a step-test method.Scand J Gastroenterol1970https://conductscience.org/library/papers/4917141PubMed
111,167,869pH dependence of acid secretion and gastrin release in normal and ulcer subjects.J Clin Invest1975https://conductscience.org/library/papers/1167869PubMed
121,116,670Amino terminal gastrin fragment in serum of Zollinger-Ellison syndrome patients.Gastroenterology1975https://conductscience.org/library/papers/1116670PubMed
135,444,167Potentiation of acid output in man by a distention stimulus.Gastroenterology1970https://conductscience.org/library/papers/5444167PubMed

Cited by33

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 138 citations.

PMIDTitleJournalYearIn PapersSource
40,427,747The Role of Somatostatin in the Gastrointestinal Tract.Biology (Basel)2025https://conductscience.org/library/papers/40427747PubMed
37,570,326Effects of Bit Chewing on Gastric Emptying, Small Intestinal Transit, and Orocecal Transit Times in Clinically Normal Horses.Animals (Basel)2023https://conductscience.org/library/papers/37570326PubMed
36,422,994The elusive cephalic phase insulin response: triggers, mechanisms, and functions.Physiol Rev2023https://conductscience.org/library/papers/36422994PubMed
34,249,327Olfaction and Aging: A Review of the Current State of Research and Future Directions.Iperception2021https://conductscience.org/library/papers/34249327PubMed
28,696,284Caffeine induces gastric acid secretion via bitter taste signaling in gastric parietal cells.Proc Natl Acad Sci U S A2017https://conductscience.org/library/papers/28696284PubMed
24,868,281Pragmatically on the sense of taste - a short treatise based on culinary art.Prz Gastroenterol2013https://conductscience.org/library/papers/24868281PubMed
20,438,741Modified sham feeding of sweet solutions in women with anorexia nervosa.Physiol Behav2010https://conductscience.org/library/papers/20438741PubMed
18,773,914Modified sham feeding of sweet solutions in women with and without bulimia nervosa.Physiol Behav2009https://conductscience.org/library/papers/18773914PubMed
18,026,575The effect of sham feeding on neurocardiac regulation in healthy human volunteers.Can J Gastroenterol2007https://conductscience.org/library/papers/18026575PubMed
17,608,267Successful weight loss surgery improves eating control and energy metabolism: a review of the evidence.Obes Surg2007https://conductscience.org/library/papers/17608267PubMed
16,520,096Role of brainstem TRH/TRH-R1 receptors in the vagal gastric cholinergic response to various stimuli including sham-feeding.Auton Neurosci2006https://conductscience.org/library/papers/16520096PubMed
8,794,783Role of sham feeding in postprandial changes of gastric myoelectrical activity.Dig Dis Sci1996https://conductscience.org/library/papers/8794783PubMed
8,472,978Cholecystokinin in the control of gastric acid secretion in man.Gut1993https://conductscience.org/library/papers/8472978PubMed
8,404,408Vagal effects on acid and pepsin secretion and serum gastrin in duodenal ulcer and controls.Dig Dis Sci1993https://conductscience.org/library/papers/8404408PubMed
7,359,444Reflex excitation of antral motility induced by gastric distension in the ferret.J Physiol1980https://conductscience.org/library/papers/7359444PubMed
7,353,458Influence of glucose on cephalic-vagal-stimulated gastric acid secretion in man.Dig Dis Sci1980https://conductscience.org/library/papers/7353458PubMed
7,067,583Effect of an opiate antagonist (naloxone) on the gastric acid secretory response to sham feeding, pentagastrin, and histamine in man.Dig Dis Sci1982https://conductscience.org/library/papers/7067583PubMed
6,797,873Gastric secretory and plasma hormonal responses to sham-feeding of varying duration in patients with duodenal ulcer.Gut1981https://conductscience.org/library/papers/6797873PubMed
6,707,197An evaluation of the importance of gastric acid secretion in the absorption of dietary calcium.J Clin Invest1984https://conductscience.org/library/papers/6707197PubMed
4,018,642Gastric acid and pancreatic polypeptide responses to modified sham feeding: indication of an increased basal vagal tone in a subgroup of duodenal ulcer patients.Gut1985https://conductscience.org/library/papers/4018642PubMed

See all 33 cited by

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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