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Paper · 87484

Mechanisms of regulation of cell-mediated immunity. IV. Azobenzenearsonate-specific suppressor factor(s) bear cross-reactive idiotypic determinants the expression of which is linked to the heavy-chain allotype linkage group of genes.

Bach BA and 3 others. J Exp Med, 1979. Cited by 127 papers, by iCite.

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ConductScience Library. Mechanisms of regulation of cell-mediated immunity. IV. Azobenzenearsonate-specific suppressor factor(s) bear cross-reactive idiotypic determinants the expression of which is linked to the heavy-chain allotype linkage group of genes. Papers, record 87484. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/87484

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Mechanisms of regulation of cell-mediated immunity. IV. Azobenzenearsonate-specific suppressor factor(s) bear cross-reactive idiotypic determinants the expression of which is linked to the heavy-chain allotype linkage group of genes.
PubMed
Journal
J Exp Med
PubMed
Year
1979
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
127
iCite
Relative citation ratio, by iCite
2.86
iCite
Revised in PubMed
2019-05-08
PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Bach BAB A
2Greene MIM I
3Benacerraf BB
4Nisonoff AA

Source PubMed

Topics15

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Azo CompoundsMajor topic
Immunoglobulin AllotypesMajor topic
Immunoglobulin Heavy ChainsMajor topic
Major Histocompatibility ComplexMajor topic
T-LymphocytesMajor topic
p-AzobenzenearsonateMajor topic
Animals
Cross Reactions
Epitopes
Female
Genetic Linkage
Hypersensitivity, Delayed
Immunoglobulin Idiotypes
Mice
Mice, Inbred Strains

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References20

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
1107,261Shared idiotypic determinants on antibodies and T-cell-derived suppressor factor specific for the random terpolymer L-glutamic acid60-L-alanine30-L-tyrosine10.J Exp Med1979https://conductscience.org/library/papers/107261PubMed
21,085,339
Properties of the antigen-specific suppressive T-cell factor in the regulation of antibody response of the mouse. IV. Special subregion assignment of the gene(s) that codes for the suppressive T-cell factor in the H-2 histocompatibility complex.
J Exp Med1976https://conductscience.org/library/papers/1085339PubMed
31,101,468Properties of primed suppressor T cells and their products.Transplant Rev1975https://conductscience.org/library/papers/1101468PubMed
4129,500Regulatory mechanisms in cell-mediated immune responses. III. I-region control of suppressor cell interaction with responder cells in mixed lymphocyte reactions.J Exp Med1976https://conductscience.org/library/papers/129500PubMed
5308,978Specific suppressive factors produced by hybridomas derived from the fusion of enriched suppressor T cells and a T lymphoma cell line.J Exp Med1978https://conductscience.org/library/papers/308978PubMed
6312,894Mechanisms of regulation of cell-mediated immunity. III. The characterization of azobenzenearsonate-specific suppressor T-cell-derived-suppressor factors.J Exp Med1979https://conductscience.org/library/papers/312894PubMed
74,110,016Quantitative investigations of idiotypic antibodies. VI. Idiotypic specificity as a potential genetic marker for the variable regions of mouse immunoglobulin polypeptide chains.J Exp Med1972https://conductscience.org/library/papers/4110016PubMed
84,120,094Evidence for the linkage of the IGC H locus to a gene controlling the idiotypic specificity of anti-p-azophenylarsonate antibodies in strain A mice.J Exp Med1973https://conductscience.org/library/papers/4120094PubMed
94,120,895Distribution of a cross-reactive idiotypic specificity in inbred strains of mice.J Exp Med1973https://conductscience.org/library/papers/4120895PubMed
10412,192Segregation at a locus determining an immunoglobulin genetic marker for the light chain variable region affects inheritance of expression of an idiotype.Proc Natl Acad Sci U S A1977https://conductscience.org/library/papers/412192PubMed

Cited by49

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 127 citations.

PMIDTitleJournalYearIn PapersSource
21,151,813Anti-ids in allergy: timeliness of a classic concept.World Allergy Organ J2010https://conductscience.org/library/papers/21151813PubMed
18,154,615Special regulatory T-cell review: A rose by any other name: from suppressor T cells to Tregs, approbation to unbridled enthusiasm.Immunology2008https://conductscience.org/library/papers/18154615PubMed
7,327,624Complementation of allotype- and nonallotype-linked genes in the induction of low-zone tolerance to phage fd.Immunogenetics1981https://conductscience.org/library/papers/7327624PubMed
7,175,441A search for messenger RNA molecules bearing immunoglobulin VH nucleotide sequences in T cells.J Exp Med1982https://conductscience.org/library/papers/7175441PubMed
7,022,711Genetic determinants of autoimmune chronic active hepatitis.Springer Semin Immunopathol1980https://conductscience.org/library/papers/7022711PubMed
7,019,373Hapten-specific T cell responses to 4-hydroxy-3-nitrophenyl acetyl. VII. Idiotype-specific suppression of plaque-forming cell responses.J Exp Med1981https://conductscience.org/library/papers/7019373PubMed
6,966,320Selective suppression of the major idiotypic component of an antihapten response by soluble T cell-derived factors with idiotypic or anti-idiotypic receptors.J Exp Med1980https://conductscience.org/library/papers/6966320PubMed
6,792,727Helper and suppressor T cell factors.Springer Semin Immunopathol1980https://conductscience.org/library/papers/6792727PubMed
6,606,014
Antigen-specific suppressor T cell interactions. II. Characterization of two different types of suppressor T cell factors specific for L-glutamic acid50-L-tyrosine50 (GT) and L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT).
J Exp Med1983https://conductscience.org/library/papers/6606014PubMed
6,600,236Regulation of immunoglobulin E antibody synthesis in man by antiidiotypic antibodies.J Clin Invest1983https://conductscience.org/library/papers/6600236PubMed

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Genes0

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None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

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None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

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  • ClinicalTrials.govNo license stated
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  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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