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Paper · 877134

Dissociation between the adjuvant vs mitogenic activity of a synthetic muramyl dipeptide for murine splenocytes.

Specter S and 2 others. Proc Soc Exp Biol Med, 1977. Cited by 49 papers, by iCite.

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ConductScience Library. Dissociation between the adjuvant vs mitogenic activity of a synthetic muramyl dipeptide for murine splenocytes. Papers, record 877134. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/877134

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Dissociation between the adjuvant vs mitogenic activity of a synthetic muramyl dipeptide for murine splenocytes.
PubMed
Journal
Proc Soc Exp Biol Med
PubMed
Year
1977
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
49
iCite
Relative citation ratio, by iCite
1.91
iCite
Revised in PubMed
2020-09-30
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Specter SS
2Friedman HH
3Chedid LL

Source PubMed

Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Adjuvants, ImmunologicMajor topic
Antibody FormationMajor topic
DipeptidesMajor topic
Lymphocyte ActivationMajor topic
MitogensMajor topic
Animals
Cells, Cultured
Lipopolysaccharides
Male
Mice
Polysaccharides, Bacterial
Spleen
Structure-Activity Relationship

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by12

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 49 citations.

PMIDTitleJournalYearIn PapersSource
17,422,948Adjuvants et stimulants de l'immunité: propriétés immunorégulatrices du muramyl-dipeptide, des corynébactéries anaérobies et du diéthyldithiocarbamate de sodium.Can Vet J1988https://conductscience.org/library/papers/17422948PubMed
9,000,596Transplantable rat thyroid cancer cell line FRTC transformed with muramyl dipeptide.Br J Cancer1997https://conductscience.org/library/papers/9000596PubMed
7,439,991Effects of treatment with muramyl dipeptide and certain of its analogs on resistance to Listeria monocytogenes in mice.Infect Immun1980https://conductscience.org/library/papers/7439991PubMed
7,216,470Effects of muramyl dipeptide treatment on resistance to infection with Toxoplasma gondii in mice.Infect Immun1981https://conductscience.org/library/papers/7216470PubMed
7,054,119
Correlation between in vivo anti-Pseudomonas and anti-Candida activities and clearance of carbon by the reticuloendothelial system for various muramyl dipeptide analogs, using normal and immunosuppressed mice.
Infect Immun1982https://conductscience.org/library/papers/7054119PubMed
7,035,868Muramyl peptides. Chemical structure, biological activity and mechanism of action.Mol Cell Biochem1981https://conductscience.org/library/papers/7035868PubMed
7,019,079Stimulation of nonspecific resistance to infection induced by 6-O-acyl muramyl dipeptide analogs in mice.Infect Immun1981https://conductscience.org/library/papers/7019079PubMed
6,776,530
Efficient genetically controlled formation of antibody to a synthetic antigen [poly(LTyr, LGlu)-poly(DLAla)- -poly(LLys)] covalently bound to a synthetic adjuvant (N-acetylmuramyl-L-alanyl-D-isoglutamine).
Proc Natl Acad Sci U S A1980https://conductscience.org/library/papers/6776530PubMed
6,744,667Regulation by muramyl dipeptide (MDP) of the lymphoproliferative responses and polyclonal activation of human peripheral blood mononuclear cells.Clin Exp Immunol1984https://conductscience.org/library/papers/6744667PubMed
6,155,329Failure of synthetic muramyl dipeptide to increase antibacterial resistance.Infect Immun1980https://conductscience.org/library/papers/6155329PubMed

1 to 10 of 12

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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