Paper · 8985334

Sequence identity of the terminal redundancies on the minus-strand DNA template is necessary but not sufficient for the template switch during hepadnavirus plus-strand DNA synthesis.

Loeb DD and 2 others. J Virol, 1997. Cited by 27 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Sequence identity of the terminal redundancies on the minus-strand DNA template is necessary but not sufficient for the template switch during hepadnavirus plus-strand DNA synthesis. Papers, record 8985334. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/8985334

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Sequence identity of the terminal redundancies on the minus-strand DNA template is necessary but not sufficient for the template switch during hepadnavirus plus-strand DNA synthesis.; PubMed
Journal: J Virol; PubMed
Year: 1997; PubMed
Publication types: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/8985334/; PubMed
DOI: https://doi.org/10.1128/jvi.71.1.152-160.1997; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC191035/; PubMed
The journal: https://conductscience.org/library/journal-index/0113724; PubMed
Citations, by iCite: 27; iCite
Relative citation ratio, by iCite: 0.48; iCite
Revised in PubMed: 2020-07-24; PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Loeb DD	D D
2	Gulya KJ	K J
3	Tian R	R

Source PubMed

Topics8

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
DNA Replication	Major topic
DNA, Single-Stranded	Major topic
DNA, Viral	Major topic
Hepatitis B Virus, Duck	Major topic
Templates, Genetic	Major topic
Virus Replication	Major topic
Animals
Ducks

Source PubMed

Grants4

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by	Source
CA07175	NCI NIH HHS	United States	P01CA007175	PubMed and NIH	NIH RePORTER
CA22443	NCI NIH HHS	United States	P01CA022443	PubMed and NIH	NIH RePORTER
GM50263	NIGMS NIH HHS	United States	R29GM050263	PubMed and NIH	NIH RePORTER
			P30CA007175	NIH	NIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References20

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	7,438,207	Hepatitis B virus contains protein attached to the 5' terminus of its complete DNA strand.	Cell	1980	https://conductscience.org/library/papers/7438207	PubMed
2	7,474,104	Transfer of the minus strand of DNA during hepadnavirus replication is not invariable but prefers a specific location.	J Virol	1995	https://conductscience.org/library/papers/7474104	PubMed
3	8,627,750	A bulged region of the hepatitis B virus RNA encapsidation signal contains the replication origin for discontinuous first-strand DNA synthesis.	J Virol	1996	https://conductscience.org/library/papers/8627750	PubMed
4	6,183,006	Mechanism of release of the avian rotavirus tRNATrp primer molecule from viral DNA by ribonuclease H during reverse transcription.	Cell	1982	https://conductscience.org/library/papers/6183006	PubMed
5	6,292,498	Virion DNA of ground squirrel hepatitis virus: structural analysis and molecular cloning.	J Virol	1982	https://conductscience.org/library/papers/6292498	PubMed
6	6,823,008	Protein covalently bound to minus-strand DNA intermediates of duck hepatitis B virus.	J Virol	1983	https://conductscience.org/library/papers/6823008	PubMed
7	3,981,148	Comparative sequence analysis of duck and human hepatitis B virus genomes.	J Med Virol	1985	https://conductscience.org/library/papers/3981148	PubMed
8	2,416,950	Evidence that a capped oligoribonucleotide is the primer for duck hepatitis B virus plus-strand DNA synthesis.	J Virol	1986	https://conductscience.org/library/papers/2416950	PubMed
9	3,961,490	Biochemical and genetic evidence for the hepatitis B virus replication strategy.	Science	1986	https://conductscience.org/library/papers/3961490	PubMed
10	3,806,799	Replication strategy of human hepatitis B virus.	J Virol	1987	https://conductscience.org/library/papers/3806799	PubMed

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Cited by22

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 27 citations.

PMID	Title	Journal	Year	In Papers	Source
39,913,382	Host 3' flap endonuclease Mus81 plays a critical role in trimming the terminal redundancy of hepatitis B virus relaxed circular DNA during covalently closed circular DNA formation.	PLoS Pathog	2025	https://conductscience.org/library/papers/39913382	PubMed
19,956,651	Mechanism for CCC DNA synthesis in hepadnaviruses.	PLoS One	2009	https://conductscience.org/library/papers/19956651	PubMed
17,531,265	The sequence of the RNA primer and the DNA template influence the initiation of plus-strand DNA synthesis in hepatitis B virus.	J Mol Biol	2007	https://conductscience.org/library/papers/17531265	PubMed
17,056,086	Complementarity between epsilon and phi sequences in pregenomic RNA influences hepatitis B virus replication efficiency.	Virology	2007	https://conductscience.org/library/papers/17056086	PubMed
16,051,809	Identification of an essential molecular contact point on the duck hepatitis B virus reverse transcriptase.	J Virol	2005	https://conductscience.org/library/papers/16051809	PubMed
15,220,419	Three novel cis-acting elements required for efficient plus-strand DNA synthesis of the hepatitis B virus genome.	J Virol	2004	https://conductscience.org/library/papers/15220419	PubMed
15,163,718	A novel cis-acting element facilitates minus-strand DNA synthesis during reverse transcription of the hepatitis B virus genome.	J Virol	2004	https://conductscience.org/library/papers/15163718	PubMed
14,694,095	cis-Acting sequences that contribute to the synthesis of relaxed-circular DNA of human hepatitis B virus.	J Virol	2004	https://conductscience.org/library/papers/14694095	PubMed
14,610,165	Template switches during plus-strand DNA synthesis of duck hepatitis B virus are influenced by the base composition of the minus-strand terminal redundancy.	J Virol	2003	https://conductscience.org/library/papers/14610165	PubMed
14,610,164	The conformation of the 3' end of the minus-strand DNA makes multiple contributions to template switches during plus-strand DNA synthesis of duck hepatitis B virus.	J Virol	2003	https://conductscience.org/library/papers/14610164	PubMed

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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