Paper · 9539645

Flow cytometric method to detect lymphocyte transformation in drug-allergic hepatic injury.

Ikeda T and 7 others. Dig Dis Sci, 1998. Cited by 2 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Flow cytometric method to detect lymphocyte transformation in drug-allergic hepatic injury. Papers, record 9539645. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/9539645

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Flow cytometric method to detect lymphocyte transformation in drug-allergic hepatic injury.; PubMed
Journal: Dig Dis Sci; PubMed
Year: 1998; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/9539645/; PubMed
DOI: https://doi.org/10.1023/a:1018850805536; PubMed
The journal: https://conductscience.org/library/journal-index/7902782; PubMed
Citations, by iCite: 2; iCite
Relative citation ratio, by iCite: 0.06; iCite
Revised in PubMed: 2026-10-16; PubMed

Authors8

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Ikeda T	T
2	Noguchi O	O
3	Kobayashi F	F
4	Tozuka S	S
5	Tokushima K	K
6	Sakamoto S	S
7	Marumo F	F
8	Sato C	C

Source PubMed

Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Chemical and Drug Induced Liver Injury	Major topic
Drug Hypersensitivity	Major topic
Lymphocyte Activation	Major topic
Lymphocytes	Major topic
Case-Control Studies
Female
Flow Cytometry
Humans
Interleukin-2
Male
Middle Aged
S Phase
Sensitivity and Specificity

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References26

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	6,216,284	A comparison of PGE2 effects on human suppressor cell function and on interleukin 2 function.	J Immunol	1982	https://conductscience.org/library/papers/6216284	PubMed
2	4,179,068	Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.	Scand J Clin Lab Invest Suppl	1968	https://conductscience.org/library/papers/4179068	PubMed
3	5,576,077	The ultrastructure of synchronized HeLa cells.	J Cell Sci	1971	https://conductscience.org/library/papers/5576077	PubMed
4	409,950	Prostaglandin-producing suppressor cells in Hodgkin's disease.	N Engl J Med	1977	https://conductscience.org/library/papers/409950	PubMed
5	779,818	Clinical patterns and results of radioallergosorbent test (RAST) and skin tests in penicillin allergy.	Br J Dermatol	1976	https://conductscience.org/library/papers/779818	PubMed
6	4,064,842	A method to measure the duration of DNA synthesis and the potential doubling time from a single sample.	Cytometry	1985	https://conductscience.org/library/papers/4064842	PubMed
7	2,871,443	Drug-induced hepatitis and lymphocyte transformation test in presence of prostaglandin inhibitor.	Lancet	1986	https://conductscience.org/library/papers/2871443	PubMed
8	6,444,967	Biochemical characterization of lymphocyte regulatory molecules. II. Purification of a class of rat and human lymphokines.	J Immunol	1980	https://conductscience.org/library/papers/6444967	PubMed
9	7,751,578	The lymphocyte transformation test--a debated method for the evaluation of drug allergic hepatic injury.	J Hepatol	1995	https://conductscience.org/library/papers/7751578	PubMed
10	1,378,078	Drug-specific T cells derived from patients with drug-induced allergic hepatitis.	J Immunol	1992	https://conductscience.org/library/papers/1378078	PubMed

1 to 10 of 26

See all 26 references

Cited by1

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 2 citations.

PMID	Title	Journal	Year	In Papers
28,796,198	In Vitro Assays in Severe Cutaneous Adverse Drug Reactions: Are They Still Research Tools or Diagnostic Tests Already?	Int J Mol Sci	2017	https://conductscience.org/library/papers/28796198

Source PubMed

Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes
IL2	3,558	PubTator's text mining	https://conductscience.org/library/genes/3558

Source NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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