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Paper · 97665

Organization of immunoglobulin heavy chain genes and allelic deletion model.

Honjo T and 1 other. Proc Natl Acad Sci U S A, 1978. Cited by 340 papers, by iCite.

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ConductScience Library. Organization of immunoglobulin heavy chain genes and allelic deletion model. Papers, record 97665. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/97665

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Organization of immunoglobulin heavy chain genes and allelic deletion model.
PubMed
Journal
Proc Natl Acad Sci U S A
PubMed
Year
1978
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
340
iCite
Relative citation ratio, by iCite
5.56
iCite
Revised in PubMed
2019-05-01
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Honjo TT
2Kataoka TT

Source PubMed

Topics14

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
GenesMajor topic
Immunoglobulin Heavy ChainsMajor topic
Alleles
Animals
Cell Line
Chromosome Deletion
Clone Cells
Genetic Linkage
Immunoglobulin Variable Region
Lymphocytes
Mice
Models, Biological
Myeloma Proteins
Recombination, Genetic

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References41

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
11,062,807Antibody differentiation: apparent sequence identity between variable regions shared by IgA and IgG immunoglobulins.Proc Natl Acad Sci U S A1976https://conductscience.org/library/papers/1062807PubMed
2302,188Immunoglobulin receptors on murine B lymphocytes.Cold Spring Harb Symp Quant Biol1977https://conductscience.org/library/papers/302188PubMed
3407,224Purification of immunoglobulin heavy chain messenger RNA by immunoprecipitation from the mouse myeloma tumor, MOPC-31C.J Biochem1977https://conductscience.org/library/papers/407224PubMed
4408,082Origin of immunoglobulin gene diversity: the evidence and a restriction-modification model.Cold Spring Harb Symp Quant Biol1977https://conductscience.org/library/papers/408082PubMed
5408,084Somatic changes in the content and context of immunoglobulin genes.Cold Spring Harb Symp Quant Biol1977https://conductscience.org/library/papers/408084PubMed
6408,086Synthesis of multiple immunoglobulin classes by single lymphocytes.Cold Spring Harb Symp Quant Biol1977https://conductscience.org/library/papers/408086PubMed
7408,087Functional and structural characterization of immunoglobulin on murine B lymphocytes.Cold Spring Harb Symp Quant Biol1977https://conductscience.org/library/papers/408087PubMed
84,142,557Lymphocyte commitment to Ig allotype and class.Ann Immunol (Paris)1974https://conductscience.org/library/papers/4142557PubMed
94,159,057Cellular localization of immunoglobulins with different allotypic specificities in rabbit lymphoid tissues.J Exp Med1965https://conductscience.org/library/papers/4159057PubMed
104,160,200The molecular basis of antibody formation: a paradox.Proc Natl Acad Sci U S A1965https://conductscience.org/library/papers/4160200PubMed

Cited by96

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 340 citations.

PMIDTitleJournalYearIn PapersSource
39,559,353Hypoxia-adenosinergic regulation of B cell responses.Front Immunol2024https://conductscience.org/library/papers/39559353PubMed
36,420,800Landscape of immunoglobulin heavy chain γ gene class switch recombination in patients with adult T-cell leukemia-lymphoma.Haematologica2023https://conductscience.org/library/papers/36420800PubMed
32,878,258Immunoglobulins or Antibodies: IMGT® Bridging Genes, Structures and Functions.Biomedicines2020https://conductscience.org/library/papers/32878258PubMed
31,839,985More than one antibody of individual B cells revealed by single-cell immune profiling.Cell Discov2019https://conductscience.org/library/papers/31839985PubMed
28,535,205A transcriptional serenAID: the role of noncoding RNAs in class switch recombination.Int Immunol2017https://conductscience.org/library/papers/28535205PubMed
27,502,143IgG subclass co-expression brings harmony to the quartet model of murine IgG function.Immunol Cell Biol2016https://conductscience.org/library/papers/27502143PubMed
25,234,413Characterization of denaturation and renaturation of DNA for DNA hybridization.Environ Health Toxicol2014https://conductscience.org/library/papers/25234413PubMed
24,616,512Zinc-finger protein ZFP318 is essential for expression of IgD, the alternatively spliced Igh product made by mature B lymphocytes.Proc Natl Acad Sci U S A2014https://conductscience.org/library/papers/24616512PubMed
23,307,864Regulation of AID, the B-cell genome mutator.Genes Dev2013https://conductscience.org/library/papers/23307864PubMed
22,771,392Combinatorial mechanisms regulating AID-dependent DNA deamination: interacting proteins and post-translational modifications.Semin Immunol2012https://conductscience.org/library/papers/22771392PubMed

1 to 10 of 96

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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