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Paper · 978389

Pharmacokinetics of the antiarrhythmic disopyramide in healthy humans.

Hinderling PH and 1 other. J Pharmacokinet Biopharm, 1976. Cited by 122 papers, by iCite.

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ConductScience Library. Pharmacokinetics of the antiarrhythmic disopyramide in healthy humans. Papers, record 978389. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/978389

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Pharmacokinetics of the antiarrhythmic disopyramide in healthy humans.
PubMed
Journal
J Pharmacokinet Biopharm
PubMed
Year
1976
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
122
iCite
Relative citation ratio, by iCite
7.68
iCite
Revised in PubMed
2026-10-11
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Hinderling PHP H
2Garrett ERE R

Source PubMed

Topics6

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
DisopyramideMajor topic
PyridinesMajor topic
Adult
Humans
Kinetics
Male

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References22

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
14,640,856Route of administration and drug metabolism.Eur J Pharmacol1972https://conductscience.org/library/papers/4640856PubMed
24,104,224Disopyramide phosphate: pharmacokinetic and pharmacologic relationships of a new antiarrhythmic agent.Arch Int Pharmacodyn Ther1971https://conductscience.org/library/papers/4104224PubMed
35,058,634Effects of protein bindings of drugs on areas under plasma concentration--time curves.J Pharm Sci1972https://conductscience.org/library/papers/5058634PubMed
42,520,314A formula to estimate the approximate surface area if height and weight be known. 1916.Nutrition1989https://conductscience.org/library/papers/2520314PubMed
513,921,458Endogenous creatinine clearance. A valuable clinical test of glomerular filtration and a prognostic guide in chronic renal disease.N Engl J Med1962https://conductscience.org/library/papers/13921458PubMed
65,353,263Pharmacokinetic basis for the influence of route of administration on the area under the plasma concentration-time curve.J Pharm Sci1969https://conductscience.org/library/papers/5353263PubMed
75,019,220Influence of route of administration on drug availability.J Pharm Sci1972https://conductscience.org/library/papers/5019220PubMed
85,567,579Influence of first-pass effect on availability of drugs on oral administration.J Pharm Sci1971https://conductscience.org/library/papers/5567579PubMed
105,046,835Integral coefficients of multi-compartment pharmacokinetic models. Application to chemotherapy.Chemotherapy1972https://conductscience.org/library/papers/5046835PubMed
114,698,974Pharmacokinetics of trichloroethanol and metabolites and interconversions among variously referenced pharmacokinetic parameters.J Pharm Sci1973https://conductscience.org/library/papers/4698974PubMed

1 to 10 of 22

See all 22 references

Cited by43

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 122 citations.

PMIDTitleJournalYearIn PapersSource
9,803,978Therapeutic drug monitoring: antiarrhythmic drugs.Br J Clin Pharmacol1998https://conductscience.org/library/papers/9803978PubMed
9,358,198A comparison of the pharmacokinetics of meropenem after intravenous administration by injection over 2, 3 and 5 minutes.Eur J Drug Metab Pharmacokinet1997https://conductscience.org/library/papers/9358198PubMed
7,437,241Pharmacokinetics of oral disopyramide phosphate in patients with renal impairment.Br J Clin Pharmacol1980https://conductscience.org/library/papers/7437241PubMed
7,387,819Plasma binding of disopyramide.Br J Clin Pharmacol1980https://conductscience.org/library/papers/7387819PubMed
7,363,933Comparative bioavailability of disopyramide after multiple dosing with standard capsules and controlled-release tablets.Eur J Clin Pharmacol1980https://conductscience.org/library/papers/7363933PubMed
7,356,902Enhanced metabolism and diminished efficacy of disopyramide by enzyme induction?Br J Clin Pharmacol1980https://conductscience.org/library/papers/7356902PubMed
7,356,895Quantitative analysis of the disopyramide concentration-effect relationship.Br J Clin Pharmacol1980https://conductscience.org/library/papers/7356895PubMed
7,215,416Pharmacokinetics of disopyramide in patients with imminent to moderate cardiac failure.Eur J Clin Pharmacol1981https://conductscience.org/library/papers/7215416PubMed
7,213,529The effect of enzyme induction on the metabolism of disopyramide in man.Br J Clin Pharmacol1981https://conductscience.org/library/papers/7213529PubMed
7,175,700Pharmacokinetics and pharmacodynamics of the antiarrhythmic compound MD750819 in dogs with experimentally induced arrhythmias.J Pharmacokinet Biopharm1982https://conductscience.org/library/papers/7175700PubMed

1 to 10 of 43

See all 43 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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