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Trial · NCT00000170

Occlusion Versus Pharmacologic Therapy for Moderate Amblyopia

NCT00000170, Phase 3, Completed, Jaeb Center for Health Research

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Occlusion Versus Pharmacologic Therapy for Moderate Amblyopia. Trials, record NCT00000170. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00000170

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Occlusion Versus Pharmacologic Therapy for Moderate Amblyopia
NCT number
NCT00000170
Status
Completed
Phases
Phase 3
Enrollment
419 participants, actual
Lead sponsor
Jaeb Center for Health Research
Conditions
Amblyopia
Interventions
Atropine, Eye Patch
First posted
1999-09-24
Last updated
2014-03-06

Source ClinicalTrials.gov

Registered outcomes4

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryVisual acuity in the amblyopic eye6 months
SecondaryVisual acuity in the amblyopic eye24 months
SecondaryExtended Follow-up: (Primary) To determine the long-term visual acuity outcome at age 10 years and at age 15 years in patients diagnosed with amblyopia before age 7 yearsage 10 years and age 15 years
Secondary
Extended Follow-up: To determine whether the long-term visual acuity outcome at age 10 yrs and age 15 yrs differs between patients who received patching followed by best clinical care and patients who received atropine followed by best clinical care
age 10 years and age 15 years

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers16

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
11507585BACKGROUNDPubMed
11545641BACKGROUNDPubMed
11879129BACKGROUNDPubMed
11879130BACKGROUNDPubMed
12917184BACKGROUNDPubMed
14516801BACKGROUNDPubMed
14516802BACKGROUNDPubMed
14609923BACKGROUNDPubMed
15710809BACKGROUNDPubMed
16414520BACKGROUNDPubMed

1 to 10 of 16

See all 16 papers

Grants1

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

ProjectTitlePrincipal investigatorsOrganizationFunderFiscal years
U10EY011751Pediatric Eye Disease Investigator Group Coordinating CenterKRAKER, RAYMONDJAEB CENTER FOR HEALTH RESEARCH, INC.NATIONAL EYE INSTITUTE1997 to 2018

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT00000170

GET https://conductscience.org/api/trials/v1/NCT00000170/registered