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Trial · NCT00001230

Host Response to Infection and Treatment in Filarial Diseases

NCT00001230, Active not recruiting, National Institute of Allergy and Infectious Diseases (NIAID)

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Host Response to Infection and Treatment in Filarial Diseases. Trials, record NCT00001230. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00001230

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Host Response to Infection and Treatment in Filarial Diseases
NCT number
NCT00001230
Status
Active not recruiting
Enrollment
425 participants, actual
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Conditions
Filariasis, Helminthiasis, Parasitic Infection, Mansonelliasis, Onchocerciasis
Interventions
Diethylcarbamazine
First posted
1999-11-04
Last updated
2026-10-30

Source ClinicalTrials.gov

Registered outcomes5

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryDefine the determinants of the susceptibility to filarial infection, the development of filarial disease and the beneficial or adverse response to chemotherapy10 yearsSusceptibilities to filarial infection will be determined
SecondaryTo identify clinical and biological markers of successful treatment in filarial-infected individuals10 yearsIdentification of clinical and biological markers of successful treatments
SecondaryTo characterize the immunoregulatory mechanisms at play in filaria-infected individuals10 yearsCharacterization of immunoregulatory mechanisms
SecondaryTo create a serum and cell bank for the study of filarial infections of humans both before and at fixed times following definitive treatment.10 yearsCell and serum bank will be maintained.
SecondaryTo understand the natural history of filarial infections in expatriates and other travelers and in immigrant populations10 yearsBetter understanding of natural history of infections in expatriates and travels

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers7

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
10530467BACKGROUNDPubMed
25234520BACKGROUNDPubMed
30761981BACKGROUNDPubMed
32055862DERIVEDPubMed
32561912DERIVEDPubMed
37243712DERIVEDPubMed
38587077DERIVEDPubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT00001230

GET https://conductscience.org/api/trials/v1/NCT00001230/registered