Trial · NCT00001305
Growth Hormone Therapy in Osteogenesis Imperfecta
NCT00001305, Phase 3, Completed, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); results first posted 2019-01-29
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Growth Hormone Therapy in Osteogenesis Imperfecta. Trials, record NCT00001305. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00001305
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Growth Hormone Therapy in Osteogenesis Imperfecta
- NCT number
- NCT00001305
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 42 participants, actual
- Lead sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- Conditions
- Osteogenesis Imperfecta
- Interventions
- Humatrope
- First posted
- 1999-11-04
- Last updated
- 2019-01-29
- Results first posted
- 2019-01-29
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Proportion of Subjects Who Met Criteria of Increase in Growth Rate Since Baseline. | 1 year | The proportion of subjects who met the study criteria of at least 50% increase in growth rate since baseline. |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Proportion of Subjects Who Met Criteria of Increase in Growth Rate Since Baseline. | 1 year | The analyses included only those subjects who completed 1 year of study | Participants | COUNT_OF_PARTICIPANTS |
Source ClinicalTrials.gov
Results by group1
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Proportion of Subjects Who Met Criteria of Increase in Growth Rate Since Baseline. | Growth Hormone | 25 | Participants |
Source ClinicalTrials.gov
Participant flow3
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Growth Hormone | 42 | |
| Overall Study | COMPLETED | Growth Hormone | 42 | |
| Overall Study | NOT COMPLETED | Growth Hormone | 0 |
Source ClinicalTrials.gov
Adverse events3
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| other | Headache | Nervous system disorders | Growth Hormone | 3 | 42 | 3 |
| other | Reaction to preservatives | Immune system disorders | Growth Hormone | 1 | 42 | 1 |
| serious | Suicide attempt | Psychiatric disorders | Growth Hormone | 1 | 42 | 1 |
Source ClinicalTrials.gov
Adverse event totals3
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Growth Hormone | 0 | 42 |
| Total, other adverse events | Growth Hormone | 4 | 42 |
| Total, serious adverse events | Growth Hormone | 1 | 42 |
Source ClinicalTrials.gov
Papers3
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00001305
GET https://conductscience.org/api/trials/v1/NCT00001305/registered