Trial · NCT00004467
Randomized Study of Acetylcysteine in Patients With Acute Liver Failure Not Caused by Acetaminophen
NCT00004467, Phase 3, Completed, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Randomized Study of Acetylcysteine in Patients With Acute Liver Failure Not Caused by Acetaminophen. Trials, record NCT00004467. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00004467
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Randomized Study of Acetylcysteine in Patients With Acute Liver Failure Not Caused by Acetaminophen
- NCT number
- NCT00004467
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 173 participants, actual
- Lead sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- Conditions
- Acute Liver Failure
- Interventions
- N-acetylcysteine (NAC), Placebo
- First posted
- 1999-10-19
- Last updated
- 2017-10-13
Source ClinicalTrials.gov
Registered outcomes5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Overall survival rate | 3 weeks | |
| Secondary | Survival without liver transplantation (Spontaneous Survival | 3 weeks | |
| Secondary | Transplant rate | 3 weeks | |
| Secondary | Length of hospital stay | 3 weeks | |
| Secondary | Number of organ systems showing failure | 3 weeks |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers3
The papers the trial lists on ClinicalTrials.gov.
Grants2
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|---|---|---|---|---|---|
| U01DK058369 | A Multi-Center Group to Study Acute Liver Failure | LEE, WILLIAM M; DURKALSKI, VALERIE L; FONTANA, ROBERT J; STRAVITZ, RICHARD | UT SOUTHWESTERN MEDICAL CENTER | NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES | 2005 to 2019 | NIH RePORTER |
| R01DK058369 | A MULTI-CENTER THERAPY TRIAL FOR ACUTE LIVER FAILURE | LEE, WILLIAM M | UNIVERSITY OF TEXAS SW MED CTR/DALLAS | NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES | 2000 to 2004 | NIH RePORTER |
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00004467
GET https://conductscience.org/api/trials/v1/NCT00004467/registered